Search Results - "Jáuregui, Olga"
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Characterization of the Human Exposome by a Comprehensive and Quantitative Large-Scale Multianalyte Metabolomics Platform
Published in Analytical chemistry (Washington) (20-10-2020)“…The exposome, defined as the cumulative measure of external exposures and associated biological responses throughout the lifespan, has emerged in recent years…”
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Quantifying the human diet in the crosstalk between nutrition and health by multi-targeted metabolomics of food and microbiota-derived metabolites
Published in International Journal of Obesity (01-12-2020)“…Background Metabolomics is a powerful tool for investigating the association between nutrition and health status. Although urine is commonly employed for…”
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Quantitative Dietary Fingerprinting (QDF)A Novel Tool for Comprehensive Dietary Assessment Based on Urinary Nutrimetabolomics
Published in Journal of agricultural and food chemistry (19-02-2020)“…Accurate dietary assessment is a challenge in nutritional research, needing powerful and robust tools for reliable measurement of food intake biomarkers. In…”
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A comprehensive characterisation of beer polyphenols by high resolution mass spectrometry (LC–ESI-LTQ-Orbitrap-MS)
Published in Food chemistry (15-02-2015)“…•Phenolic profile of 4 types of beer has been analyzed by high resolution mass spectrometry.•Phenolic profile among the four types of beers was very…”
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Evaluation of a Method To Characterize the Phenolic Profile of Organic and Conventional Tomatoes
Published in Journal of agricultural and food chemistry (04-04-2012)“…The present study aims to compare the phenolic profiles of organic and conventional tomatoes bought in the market. For the quantification and identification of…”
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New and Vintage Solutions To Enhance the Plasma Metabolome Coverage by LC-ESI-MS Untargeted Metabolomics: The Not-So-Simple Process of Method Performance Evaluation
Published in Analytical chemistry (Washington) (03-03-2015)“…Although LC-MS untargeted metabolomics continues to expand into exiting research domains, methodological issues have not been solved yet by the definition of…”
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Phenolic profiling of the skin, pulp and seeds of Albariño grapes using hybrid quadrupole time-of-flight and triple-quadrupole mass spectrometry
Published in Food chemistry (15-02-2014)“…•For the first time a characterisation of the phenolic compounds in skin, pulp and seed of the Albariño grape was reported.•The combination of QqToF and QqQ…”
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Mechanistically different effects of fat and sugar on insulin resistance, hypertension, and gut microbiota in rats
Published in American journal of physiology: endocrinology and metabolism (01-06-2018)“…Insulin resistance (IR) and impaired glucose tolerance (IGT) are the first manifestations of diet-induced metabolic alterations leading to Type 2 diabetes,…”
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Liquid chromatography-tandem mass spectrometry analysis of eicosanoids and related compounds in cell models
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-08-2014)“…•Eicosanoids are present at very low levels in cell systems and therefore require targeted methods for quantification.•A full understanding of how eicosanoids…”
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Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography–tandem mass spectrometry
Published in Journal of Chromatography A (23-10-2009)“…The biological properties of cocoa ( Theobroma cacao L.) polyphenols are strictly dependent on their bioavailability. A long-term cocoa feeding trial was…”
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Metabotypes of response to bariatric surgery independent of the magnitude of weight loss
Published in PloS one (01-06-2018)“…Bariatric surgery is considered the most efficient treatment for morbid obesity and its related diseases. However, its role as a metabolic modifier is not well…”
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Phenolic Profile and Hydrophilic Antioxidant Capacity as Chemotaxonomic Markers of Tomato Varieties
Published in Journal of agricultural and food chemistry (27-04-2011)“…Tomatoes (Solanum lycopersicum L.), the second most important vegetable crop worldwide, are a key component in the so-called “Mediterranean diet”, which is…”
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Urinary metabolomics of phenolic compounds reveals biomarkers of type-2 diabetes within the PREDIMED trial
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Phenolic compounds have been associated with protective effects against type-2 diabetes (T2D). We used a metabolomics approach to determine urinary phenolic…”
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Metabolomics Unveils Urinary Changes in Subjects with Metabolic Syndrome following 12-Week Nut Consumption
Published in Journal of proteome research (04-11-2011)“…Through an HPLC-Q-TOF-MS-driven nontargeted metabolomics approach, we aimed to discriminate changes in the urinary metabolome of subjects with metabolic…”
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Alteration of cellular lipids and lipid metabolism markers in RTL-W1 cells exposed to model endocrine disrupters
Published in Aquatic toxicology (01-08-2015)“…•RTL-W1 cells express genes involved in lipid metabolism: CD36, FATP1, FAS, LPL, PPARβ.•Gene expression was up/down-regulated after exposure to selected…”
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Urolithins Are the Main Urinary Microbial-Derived Phenolic Metabolites Discriminating a Moderate Consumption of Nuts in Free-Living Subjects with Diagnosed Metabolic Syndrome
Published in Journal of agricultural and food chemistry (12-09-2012)“…Walnuts (Juglans regia L.), hazelnuts (Corylus avellana L.), and almonds (Prunus dulcis Mill.) are rich sources of ellagitannins and proanthocyanidins. Gut…”
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Metabolomics Technologies for the Identification and Quantification of Dietary Phenolic Compound Metabolites: An Overview
Published in Antioxidants (25-05-2021)“…In the search for natural products with properties that may protect against or slow down chronic and degenerative diseases (e.g., cancer, and cardiovascular…”
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Screening of the polyphenol content of tomato-based products through accurate-mass spectrometry (HPLC–ESI-QTOF)
Published in Food chemistry (01-12-2011)“…► The phenolic fingerprint identified by HPLC–QTOF showed differences among tomato by-products. ► HPLC–QTOF enabled 47 polyphenols to be identified in tomato…”
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Enhanced determination of abscisic acid (ABA) and abscisic acid glucose ester (ABA-GE) in Cistus albidus plants by liquid chromatography–mass spectrometry in tandem mode
Published in Plant physiology and biochemistry (01-04-2009)“…An improved, quick and simple method for the extraction and quantification of the phytohormones (+)-abscisic acid (ABA) and its major glucose conjugate,…”
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Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole- In Vitro and In Vivo Investigations
Published in Frontiers in pharmacology (2020)“…Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including…”
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