Search Results - "Jászai, József"

Loss of the Cholesterol-Binding Protein Prominin-1/CD133 Causes Disk Dysmorphogenesis and Photoreceptor Degeneration by Zacchigna, Serena, Oh, Hideyasu, Wilsch-Brauninger, Michaela, Missol-Kolka, Ewa, Jaszai, Jozsef, Jansen, Sandra, Tanimoto, Naoyuki, Tonagel, Felix, Seeliger, Mathias, Huttner, Wieland B, Corbeil, Denis, Dewerchin, Mieke, Vinckier, Stefan, Moons, Lieve, Carmeliet, Peter

“…Prominin-1/CD133 (Prom-1) is a commonly used marker of neuronal, vascular, hematopoietic and other stem cells, yet little is known about its biological role…”
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Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3 by Jászai, József, Thamm, Kristina, Karbanová, Jana, Janich, Peggy, Fargeas, Christine A., Huttner, Wieland B., Corbeil, Denis

“…Prominins (proms) are transmembrane glycoproteins conserved throughout the animal kingdom. They are associated with plasma membrane protrusions, such as…”
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VEGF‐Trap is a potent modulator of vasoregenerative responses and protects dopaminergic amacrine network integrity in degenerative ischemic neovascular retinopathy by Rojo Arias, Jesús E., Economopoulou, Matina, Juárez López, David A., Kurzbach, Anica, Au Yeung, Kwan H., Englmaier, Vanessa, Merdausl, Marie, Schaarschmidt, Martin, Ader, Marius, Morawietz, Henning, Funk, Richard H. W., Jászai, József

“…Retinal hypoxia triggers abnormal vessel growth and microvascular hyper‐permeability in ischemic retinopathies. Whereas vascular endothelial growth factor A…”
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The Stem Cell Marker CD133 (Prominin-1) Is Expressed in Various Human Glandular Epithelia by Karbanova, Jana, Missol-Kolka, Ewa, Fonseca, Ana-Violeta, Lorra, Christoph, Janich, Peggy, Hollerova, Hana, Jaszai, Jozsef, Ehrmann, Jiri, Kolar, Zdenek, Liebers, Cornelia, Arl, Stefanie, Subrtova, Danuse, Freund, Daniel, Mokry, Jaroslav, Huttner, Wieland B, Corbeil, Denis

“…Human prominin-1 (CD133) is expressed by various stem and progenitor cells originating from diverse sources. In addition to stem cells, its mouse ortholog is…”
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Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain by Jászai, József, Graupner, Sylvi, Tanaka, Elly M, Funk, Richard H W, Huttner, Wieland B, Brand, Michael, Corbeil, Denis

“…In mammals, embryonic neural progenitors as well as adult neural stem cells can be prospectively isolated based on the cell surface expression of prominin-1…”
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Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells by Corbeil, Denis, Joester, Angret, Fargeas, Christine A., Jászai, József, Garwood, Jeremy, Hellwig, Andrea, Werner, Hauke B., Huttner, Wieland B.

“…Prominin‐1 (CD133) is a cholesterol‐interacting pentaspan membrane glycoprotein specifically associated with plasma membrane protrusions. Prominin‐1 is…”
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Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species by Jászai, József, Fargeas, Christine A, Graupner, Sylvi, Tanaka, Elly M, Brand, Michael, Huttner, Wieland B, Corbeil, Denis

“…Besides being a marker of various somatic stem cells in mammals, prominin-1 (CD133) plays a role in maintaining the photoreceptor integrity since mutations in…”
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The Stem Cell Marker Prominin‐1/CD133 on Membrane Particles in Human Cerebrospinal Fluid Offers Novel Approaches for Studying Central Nervous System Disease by Huttner, Hagen B., Janich, Peggy, Köhrmann, Martin, Jászai, József, Siebzehnrubl, Florian, Blümcke, Ingmar, Suttorp, Meinolf, Gahr, Manfred, Kuhnt, Daniela, Nimsky, Christopher, Krex, Dietmar, Schackert, Gabriele, Löwenbrück, Kai, Reichmann, Heinz, Jüttler, Eric, Hacke, Werner, Schellinger, Peter D., Schwab, Stefan, Wilsch‐Bräuninger, Michaela, Marzesco, Anne‐Marie, Corbeil, Denis

“…Cerebrospinal fluid (CSF) is routinely used for diagnosing and monitoring neurological diseases. The CSF proteins used so far for diagnostic purposes (except…”
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Prominin-2 is a novel marker of distal tubules and collecting ducts of the human and murine kidney by Jászai, József, Farkas, Lilla M, Fargeas, Christine A, Janich, Peggy, Haase, Michael, Huttner, Wieland B, Corbeil, Denis

“…Prominin-1 (CD133) and its paralogue, prominin-2, are pentaspan membrane glycoproteins that are strongly expressed in the kidney where they have been…”
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Isthmus-to-midbrain transformation in the absence of midbrain-hindbrain organizer activity by Jászai, József, Reifers, Frank, Picker, Alexander, Langenberg, Tobias, Brand, Michael

“…In zebrafish acerebellar ( ace ) embryos, because of a point mutation in fgf8 , the isthmic constriction containing the midbrain-hindbrain boundary (MHB)…”
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Gene expression profile of the murine ischemic retina and its response to Aflibercept (VEGF-Trap) by Rojo Arias, Jesús Eduardo, Jászai, József

“…Ischemic retinal dystrophies are leading causes of acquired vision loss. Although the dysregulated expression of the hypoxia-responsive VEGF-A is a major…”
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Trends and Challenges in Tumor Anti-Angiogenic Therapies by Jászai, József, Schmidt, Mirko H H

“…Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a hallmark of solid tumors. This process is driven by an imbalance between…”
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Induction of vascular endothelial growth factor‐A165a in human retinal and endothelial cells in response to glyoxal by Morawietz, Henning, Frenzel, Annika, Mieting, Alice, Goettsch, Winfried, Valtink, Monika, Roehlecke, Cora, Jászai, József, Funk, Richard H. W., Becker, Klio A., Engelmann, Katrin

“…Low‐density lipoprotein (LDL) apheresis is effective and safe for patients with diabetes, proteinuria, and dyslipidemia. Diabetes mellitus is accompanied by…”
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Induction of vascular endothelial growth factor-A 165a in human retinal and endothelial cells in response to glyoxal by Morawietz, Henning, Frenzel, Annika, Mieting, Alice, Goettsch, Winfried, Valtink, Monika, Roehlecke, Cora, Jászai, József, Funk, Richard H W, Becker, Klio A, Engelmann, Katrin

“…Low-density lipoprotein (LDL) apheresis is effective and safe for patients with diabetes, proteinuria, and dyslipidemia. Diabetes mellitus is accompanied by…”
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Deciphering the roles of prominins in the visual system by Corbeil, Denis, Fargeas, Christine A., Jászai, József

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CD133 might be a pan marker of epithelial cells with dedifferentiation capacity by Corbeil, Denis, Fargeas, Christine A., Jászai, József

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Prominin‐1 expression in the testis/epididymis and fertility by Fargeas, Christine A., Jászai, József, Corbeil, Denis

“…The contribution of Prominin‐1 (aka CD133) to male fertility has recently been (re)investigated, with contradictory results. Early findings, essential for…”
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Prominin-1 (CD133): Molecular and Cellular Features Across Species by Corbeil, Denis, Karbanová, Jana, Fargeas, Christine A, Jászai, József

“…Our knowledge of the first member of the prominin family is growing rapidly as the clinical value of prominin-1 (CD133) increases with its ever-wider use as a…”
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VEGF-Trap Modulates Retinal Inflammation in the Murine Oxygen-Induced Retinopathy (OIR) Model by Rojo Arias, Jesús Eduardo, Englmaier, Vanessa Elisabeth, Jászai, József

“…Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for retinal neovascular diseases, which represent the most prevalent causes…”
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CD133 and membrane microdomains：Old facets for future hypotheses by Fargeas, Christine A, Karbanová, Jana, Jászai, József, Corbeil, Denis

“…Understanding all facets of membrane microdomains in normal and cancerous cells within the digestive tract is highly important,not only from a clinical point…”
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