Search Results - "JØRGENSEN, Marit E"

Greenlandic Inuit show genetic signatures of diet and climate adaptation by Fumagalli, Matteo, Moltke, Ida, Grarup, Niels, Racimo, Fernando, Bjerregaard, Peter, Jørgensen, Marit E., Korneliussen, Thorfinn S., Gerbault, Pascale, Skotte, Line, Linneberg, Allan, Christensen, Cramer, Brandslund, Ivan, Jørgensen, Torben, Huerta-Sánchez, Emilia, Schmidt, Erik B., Pedersen, Oluf, Hansen, Torben, Albrechtsen, Anders, Nielsen, Rasmus

“…The indigenous people of Greenland, the Inuit, have lived for a long time in the extreme conditions of the Arctic, including low annual temperatures, and with…”
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A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes by Moltke, Ida, Grarup, Niels, Jørgensen, Marit E., Bjerregaard, Peter, Treebak, Jonas T., Fumagalli, Matteo, Korneliussen, Thorfinn S., Andersen, Marianne A., Nielsen, Thomas S., Krarup, Nikolaj T., Gjesing, Anette P., Zierath, Juleen R., Linneberg, Allan, Wu, Xueli, Sun, Guangqing, Jin, Xin, Al-Aama, Jumana, Wang, Jun, Borch-Johnsen, Knut, Pedersen, Oluf, Nielsen, Rasmus, Albrechtsen, Anders, Hansen, Torben

“…An association mapping study of type-2-diabetes-related quantitative traits in the Greenlandic population identified a common variant in TBC1D4 that increases…”
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GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study by Færch, Kristine, Torekov, Signe S, Vistisen, Dorte, Johansen, Nanna B, Witte, Daniel R, Jonsson, Anna, Pedersen, Oluf, Hansen, Torben, Lauritzen, Torsten, Sandbæk, Annelli, Holst, Jens Juul, Jørgensen, Marit E

“…The role of glucose-stimulated release of GLP-1 in the development of obesity and type 2 diabetes is unclear. We assessed GLP-1 response to oral glucose in a…”
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Risk of Cardiovascular Disease and Death in Individuals With Prediabetes Defined by Different Criteria: The Whitehall II Study by Vistisen, Dorte, Witte, Daniel R, Brunner, Eric J, Kivimäki, Mika, Tabák, Adam, Jørgensen, Marit E, Færch, Kristine

“…We compared the risk of cardiovascular disease (CVD) and all-cause mortality in subgroups of prediabetes defined by fasting plasma glucose (FPG), 2-h plasma…”
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Alcohol drinking patterns and risk of diabetes: a cohort study of 70,551 men and women from the general Danish population by Holst, Charlotte, Becker, Ulrik, Jørgensen, Marit E., Grønbæk, Morten, Tolstrup, Janne S.

“…Aims/hypothesis Alcohol consumption is inversely associated with diabetes, but little is known about the role of drinking patterns. We examined the association…”
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Severe mental illness and the risk of diabetes complications. A nationwide register-based cohort study by Scheuer, Stine H, Kosjerina, Vanja, Lindekilde, Nanna, Pouwer, Frans, Carstensen, Bendix, Jørgensen, Marit E, Benros, Michael E, Andersen, Gregers S

“…Persons with severe mental illness (SMI) are at increased risk to develop type 2 diabetes. It is unclear whether persons with diabetes and SMI are also at…”
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Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels by Mahendran, Yuvaraj, Jonsson, Anna, Have, Christian T., Allin, Kristine H., Witte, Daniel R., Jørgensen, Marit E., Grarup, Niels, Pedersen, Oluf, Kilpeläinen, Tuomas O., Hansen, Torben

“…Aims/hypothesis Fasting plasma levels of branched-chain amino acids (BCAAs) are associated with insulin resistance, but it remains unclear whether there is a…”
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Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes by Grarup, Niels, Moltke, Ida, Andersen, Mette K., Dalby, Maria, Vitting-Seerup, Kristoffer, Kern, Timo, Mahendran, Yuvaraj, Jørsboe, Emil, Larsen, Christina V. L., Dahl-Petersen, Inger K., Gilly, Arthur, Suveges, Daniel, Dedoussis, George, Zeggini, Eleftheria, Pedersen, Oluf, Andersson, Robin, Bjerregaard, Peter, Jørgensen, Marit E., Albrechtsen, Anders, Hansen, Torben

“…We have identified a variant in ADCY3 (encoding adenylate cyclase 3) associated with markedly increased risk of obesity and type 2 diabetes in the Greenlandic…”
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Risk Factors for the Presence and Progression of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes: ADDITION-Denmark by Andersen, Signe T, Witte, Daniel R, Fleischer, Jesper, Andersen, Henning, Lauritzen, Torsten, Jørgensen, Marit E, Jensen, Troels S, Pop-Busui, Rodica, Charles, Morten

“…To examine the course of cardiovascular autonomic neuropathy (CAN) and related cardiometabolic risk factors in patients with type 2 diabetes. CAN and…”
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Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the Whitehall II cohort study by Vistisen, Dorte, Kivimäki, Mika, Perreault, Leigh, Hulman, Adam, Witte, Daniel R., Brunner, Eric J., Tabák, Adam, Jørgensen, Marit E., Færch, Kristine

“…Aims/hypothesis Reversion from prediabetes to normoglycaemia is accompanied by an improvement in cardiovascular risk factors, but it is unclear whether this…”
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Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes by Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Sulem, Patrick, Helgason, Hannes, Grarup, Niels, Sigurdsson, Asgeir, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Magnusson, Olafur T, Gudjonsson, Sigurjon A, Justesen, Johanne M, Harder, Marie N, Jørgensen, Marit E, Christensen, Cramer, Brandslund, Ivan, Sandbæk, Annelli, Lauritzen, Torsten, Vestergaard, Henrik, Linneberg, Allan, Jørgensen, Torben, Hansen, Torben, Daneshpour, Maryam S, Fallah, Mohammad-Sadegh, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Azizi, Fereidoun, Benediktsson, Rafn, Masson, Gisli, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F, Pedersen, Oluf, Thorsteinsdottir, Unnur, Stefansson, Kari

“…Unnur Thorsteinsdottir, Kari Stefansson and colleagues identify low-frequency and rare sequence variants associated with elevated or reduced risk of type 2…”
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Dapagliflozin is associated with lower risk of cardiovascular events and all‐cause mortality in people with type 2 diabetes (CVD‐REAL Nordic) when compared with dipeptidyl peptidase‐4 inhibitor therapy: A multinational observational study by Persson, Frederik, Nyström, Thomas, Jørgensen, Marit E., Carstensen, Bendix, Gulseth, Hanne L., Thuresson, Marcus, Fenici, Peter, Nathanson, David, Eriksson, Jan W., Norhammar, Anna, Bodegard, Johan, Birkeland, Kåre I.

“…Aims To compare the sodium‐glucose‐cotransporter‐2 (SGLT‐2) inhibitor dapagliflozin with dipeptidyl peptidase‐4 (DPP‐4) inhibitors with regard to risk…”
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Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation by Færch, Kristine, Vistisen, Dorte, Pacini, Giovanni, Torekov, Signe S, Johansen, Nanna B, Witte, Daniel R, Jonsson, Anna, Pedersen, Oluf, Hansen, Torben, Lauritzen, Torsten, Jørgensen, Marit E, Ahrén, Bo, Holst, Jens Juul

“…Hyperinsulinemia is an adaptive mechanism that enables the maintenance of normoglycemia in the presence of insulin resistance. We assessed whether glucagon is…”
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Cardiovascular mortality and morbidity in patients with type 2 diabetes following initiation of sodium-glucose co-transporter-2 inhibitors versus other glucose-lowering drugs (CVD-REAL Nordic): a multinational observational analysis by Birkeland, Kåre I, Jørgensen, Marit E, Carstensen, Bendix, Persson, Frederik, Gulseth, Hanne L, Thuresson, Marcus, Fenici, Peter, Nathanson, David, Nyström, Thomas, Eriksson, Jan W, Bodegård, Johan, Norhammar, Anna

“…In patients with type 2 diabetes and a high cardiovascular risk profile, the sodium-glucose co-transporter-2 (SGLT2) inhibitors empagliflozin and canagliflozin…”
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Effect of duration and burden of microvascular complications on mortality rate in type 1 diabetes: an observational clinical cohort study by Bjerg, Lasse, Hulman, Adam, Carstensen, Bendix, Charles, Morten, Witte, Daniel R., Jørgensen, Marit E.

“…Aims/hypothesis The role of burden and duration of multiple microvascular complications on mortality rate has not been explored in detail in type 1 diabetes…”
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Mortality after cancer among patients with diabetes mellitus: effect of diabetes duration and treatment by Ranc, Kristina, Jørgensen, Marit E., Friis, Søren, Carstensen, Bendix

“…Aims/hypothesis The prognostic role of different diabetes treatment types has not been studied in detail. We compared mortality rates among cancer patients…”
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Uncovering the Genetic History of the Present-Day Greenlandic Population by Moltke, Ida, Fumagalli, Matteo, Korneliussen, Thorfinn S., Crawford, Jacob E., Bjerregaard, Peter, Jørgensen, Marit E., Grarup, Niels, Gulløv, Hans Christian, Linneberg, Allan, Pedersen, Oluf, Hansen, Torben, Nielsen, Rasmus, Albrechtsen, Anders

“…Because of past limitations in samples and genotyping technologies, important questions about the history of the present-day Greenlandic population remain…”
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Evidence of a liver–alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids by Wewer Albrechtsen, Nicolai J., Færch, Kristine, Jensen, Troels M., Witte, Daniel R., Pedersen, Jens, Mahendran, Yuvaraj, Jonsson, Anna E., Galsgaard, Katrine D., Winther-Sørensen, Marie, Torekov, Signe S., Lauritzen, Torsten, Pedersen, Oluf, Knop, Filip K., Hansen, Torben, Jørgensen, Marit E., Vistisen, Dorte, Holst, Jens J.

“…Aims/hypothesis The secretion of glucagon is controlled by blood glucose and inappropriate secretion of glucagon contributes to hyperglycaemia in diabetes…”
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Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes by Buckley, Matthew T, Racimo, Fernando, Allentoft, Morten E, Jensen, Majken K, Jonsson, Anna, Huang, Hongyan, Hormozdiari, Farhad, Sikora, Martin, Marnetto, Davide, Eskin, Eleazar, Jørgensen, Marit E, Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Kraft, Peter, Willerslev, Eske, Nielsen, Rasmus

“…FADS genes encode fatty acid desaturases that are important for the conversion of short chain polyunsaturated fatty acids (PUFAs) to long chain fatty acids…”
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Time trends in mortality rates in type 1 diabetes from 2002 to 2011 by Jørgensen, Marit E., Almdal, Thomas P., Carstensen, Bendix

“…Aims/hypothesis The aim of this study was to estimate absolute and relative mortality rates in patients with type 1 diabetes at the Steno Diabetes Centre…”
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