Search Results - "Izzo, Angelo A."
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Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals
Published in British journal of pharmacology (01-03-2020)“…The nutraceuticals market is vast, encompassing many different products with inconsistent levels of evidence available to support their use. This overview…”
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Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases
Published in Phytotherapy research (01-11-2018)“…Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic herb with a 2,000‐year history of use. MT fruits contain a mixture of…”
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A Critical Approach to Evaluating Clinical Efficacy, Adverse Events and Drug Interactions of Herbal Remedies
Published in Phytotherapy research (01-05-2016)“…Systematic reviews and meta‐analyses represent the uppermost ladders in the hierarchy of evidence. Systematic reviews/meta‐analyses suggest preliminary or…”
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ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020
Published in British journal of pharmacology (01-08-2020)Get full text
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Gut Microbiota and Obesity: A Role for Probiotics
Published in Nutrients (07-11-2019)“…Nowadays, obesity is one of the most prevalent human health problems. Research from the last 30 years has clarified the role of the imbalance between energy…”
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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
Published in Trends in pharmacological sciences (Regular ed.) (01-10-2009)“…Δ9 -tetrahydrocannabinol binds cannabinoid (CB1 and CB2 ) receptors, which are activated by endogenous compounds (endocannabinoids) and are involved in a wide…”
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Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology
Published in British journal of pharmacology (01-02-2018)Get full text
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The pharmacology of TRP channels
Published in British journal of pharmacology (01-05-2014)“…This themed issue of the British Journal of Pharmacology contains review and research articles on recent advances in transient receptor potential (TRP) channel…”
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Nanoparticle Delivery Systems in the Treatment of Diabetes Complications
Published in Molecules (Basel, Switzerland) (20-11-2019)“…Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the homeostasis of blood sugar levels, being the subcutaneous injection of…”
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Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti‐inflammatory agent
Published in British journal of pharmacology (01-01-2015)“…Background and Purpose Palmitoylethanolamide (PEA) acts via several targets, including cannabinoid CB1 and CB2 receptors, transient receptor potential…”
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Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
Published in Journal of molecular medicine (Berlin, Germany) (01-08-2012)“…Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and non-psychotropic ingredient of Cannabis sativa , exerts…”
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Palmitoylethanolamide normalizes intestinal motility in a model of post‐inflammatory accelerated transit: involvement of CB1 receptors and TRPV1 channels
Published in British journal of pharmacology (01-09-2014)“…Background and Purpose Palmitoylethanolamide (PEA), a naturally occurring acylethanolamide chemically related to the endocannabinoid anandamide, interacts with…”
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Editorial: Insights in Gastrointestinal and Hepatic Pharmacology: 2021
Published in Frontiers in pharmacology (05-04-2022)Get full text
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BAT3 regulates Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis of macrophages
Published in PloS one (13-07-2012)“…HLA-B-associated transcript 3 (BAT3), also known as Scythe or BAG6, is a nuclear protein implicated in the control of apoptosis and natural killer (NK)…”
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Garlic (Allium sativum L.): Adverse effects and drug interactions in humans
Published in Molecular nutrition & food research (01-11-2007)“…Garlic (Alllium sativum L., Fam Liliaceae) is used medicinally mainly for the treatment of hypercholesterolemia and prevention of arteriosclerosis. Clinical…”
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Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis
Published in Pharmacological research (01-05-2017)“…[Display omitted] Colorectal cancer (CRC) is a major health problem in Western countries. The endocannabinoid 2-arachidonoyl-glycerol (2-AG) exerts…”
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Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis
Published in Frontiers in immunology (18-06-2020)“…The live attenuated strain, Bacille Calmette Guérin (BCG) is a potent innate immune stimulator. In the C57BL/6 mouse model of tuberculosis, BCG vaccination…”
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Fish Oil, Cannabidiol and the Gut Microbiota: An Investigation in a Murine Model of Colitis
Published in Frontiers in pharmacology (08-10-2020)“…Inflammatory bowel disorders can be associated with alterations in gut microbiota (dysbiosis) and behavioral disturbances. In experimental colitis,…”
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TNF‐Stimulated Gene‐6 Is a Key Regulator in Switching Stemness and Biological Properties of Mesenchymal Stem Cells
Published in Stem cells (Dayton, Ohio) (01-07-2019)“…Mesenchymal stem cells (MSCs) are well established to have promising therapeutic properties. TNF‐stimulated gene‐6 (TSG‐6), a potent tissue‐protective and…”
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