Search Results - "Izumi, Tomonori"

Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy by Mimura, Yusuke, Katoh, Toshihiko, Saldova, Radka, O'Flaherty, Roisin, Izumi, Tomonori, Mimura-Kimura, Yuka, Utsunomiya, Toshiaki, Mizukami, Yoichi, Yamamoto, Kenji, Matsumoto, Tsuneo, M. Rudd, Pauline

“…Glycosylation of the Fc region of IgG has a profound impact on the safety and clinical efficacy of therapeutic antibodies. While the biantennary complex-type…”
Get full text

Effects of a constant light environment on hippocampal neurogenesis and memory in mice by Fujioka, Aya, Fujioka, Takashi, Tsuruta, Ryosuke, Izumi, Tomonori, Kasaoka, Shunji, Maekawa, Tsuyoshi

“…▶ Constant light attenuates neurogenesis in the hippocampus. ▶ Attenuated neurogenesis occurs only in the granule cell layer, but not in the hilus. ▶ Constant…”
Get full text

Cell Surface Labeling and Mass Spectrometry Reveal Diversity of Cell Surface Markers and Signaling Molecules Expressed in Undifferentiated Mouse Embryonic Stem Cells by Nunomura, Kazuto, Nagano, Kohji, Itagaki, Chiharu, Taoka, Masato, Okamura, Nobuko, Yamauchi, Yoshio, Sugano, Sumio, Takahashi, Nobuhiro, Izumi, Tomonori, Isobe, Toshiaki

“…Although interactions between cell surface proteins and extracellular ligands are key to initiating embryonic stem cell differentiation to specific cell…”
Get full text

Prognostic value of biochemical markers of brain damage and oxidative stress in post-surgical aneurysmal subarachnoid hemorrhage patients by Kaneda, Kotaro, Fujita, Motoki, Yamashita, Susumu, Kaneko, Tadashi, Kawamura, Yoshikatsu, Izumi, Tomonori, Tsuruta, Ryosuke, Kasaoka, Shunji, Maekawa, Tsuyoshi

“…Abstract The aim of this study is to determine effective biochemical markers and optimal sampling timing for prediction of neurological prognosis in…”
Get full text

Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs by Oyama, Masaaki, Itagaki, Chiharu, Hata, Hiroko, Suzuki, Yutaka, Izumi, Tomonori, Natsume, Tohru, Isobe, Toshiaki, Sugano, Sumio

“…To find novel short coding sequences from accumulated full-length cDNA sequences, proteomic analysis of small proteins expressed in human leukemia K562 cells…”
Get full text

Large-scale identification of proteins expressed in mouse embryonic stem cells by Nagano, Kohji, Taoka, Masato, Yamauchi, Yoshio, Itagaki, Chiharu, Shinkawa, Takashi, Nunomura, Kazuto, Okamura, Nobuko, Takahashi, Nobuhiro, Izumi, Tomonori, Isobe, Toshiaki

“…A protein subset expressed in the mouse embryonic stem (ES) cell line, E14‐1, was characterized by mass spectrometry‐based protein identification technology…”
Get full text

MARCKS-like protein, a membrane protein identified for its expression in developing neural retina, plays a role in regulating retinal cell proliferation by Zhao, Jing, Izumi, Tomonori, Nunomura, Kazuto, Satoh, Shinya, Watanabe, Sumiko

“…Membrane proteins are expressed in a specific manner in developing tissues, and characterization of these proteins is valuable because it allows them to be…”
Get full text

Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats by Tanaka, Ryo, Fujita, Motoki, Tsuruta, Ryosuke, Fujimoto, Kenji, Aki, Hiromi Shinagawa, Kumagai, Kazumi, Aoki, Tetsuya, Kobayashi, Akihiro, Izumi, Tomonori, Kasaoka, Shunji, Yuasa, Makoto, Maekawa, Tsuyoshi

“…Objective and design The protective effects of ulinastatin, a human urinary trypsin inhibitor (UTI), against superoxide radical (O ₂ ⁻· ) generation, systemic…”
Get full text

Proteomic analysis of proteins expressing in regions of rat brain by a combination of SDS-PAGE with nano-liquid chromatography-quadrupole-time of flight tandem mass spectrometry by Katagiri, Tomoki, Hatano, Naoya, Aihara, Masamune, Kawano, Hiroo, Okamoto, Mariko, Liu, Ying, Izumi, Tomonori, Maekawa, Tsuyoshi, Nakamura, Shoji, Ishihara, Tokuhiro, Shirai, Mutsunori, Mizukami, Yoichi

“…Most biological functions controlled by the brain and their related disorders are closely associated with activation in specific regions of the brain…”
Get full text

Prothrombin and beta 2-glycoprotein I frequently contribute to antiphospholipid antibody interactions with phospholipids and the generation of abnormal waveform profiles in coagulation assays by Su, Zuowei, Izumi, Tomonori, Ortel, Thomas L

“…Transmittance waveforms are generated during clot formation on photo-optical coagulation analyzers. We previously showed that 61.5% of patients with…”
Get more information

A Demodulation Method Using a Gaussian Mixture Model For Unsynchronous Optical Camera Communication With on-off Keying by Shiraki, Yoshifumi, Sato, Takashi G., Kamamoto, Yutaka, Izumi, Tomonori, Nakahara, Yu, Kondo, Kyosuke, Moriya, Takehiro

“…We consider optical camera communication (OCC) between a camera receiver with optical lenses and distributed transmitters. This article investigates the…”
Get full text

Fine mapping of inhibitory anti-factor V antibodies using factor V C2 domain mutants. Identification of two antigenic epitopes involved in phospholipid binding by Izumi, T, Kim, S W, Greist, A, Macedo-Ribeiro, S, Fuentes-Prior, P, Bode, W, Kane, W H, Ortel, T L

“…Hemorrhagic factor V inhibitors frequently bind to the second C-type (C2) domain of factor V and interfere with phospholipid binding. To define specific…”
Get more information

Molecular and genetic mechanisms of factor XIII A subunit deficiency by Ichinose, A, Souri, M, Izumi, T, Takahashi, N

“…Factor XIII is a proenzyme for a plasma transglutaminase. Factor XIII in plasma is a tetramer (A2B2) held together by noncovalent bonds, and the A subunit…”
Get more information

Novel deletion and insertion mutations cause splicing defects, leading to severe reduction in mRNA levels of the A subunit in severe factor XIII deficiency by Izumi, T, Nagaoka, U, Saito, T, Takamatsu, J, Saito, H, Ichinose, A

“…In order to explore molecular mechanisms for factor XIII deficiency, a patient (Nagoya I) was examined at the DNA and RNA levels. Nucleotide sequence analysis…”
Get more information

A founder effect is proposed for factor XIII B subunit deficiency caused by the insertion of triplet AAC in exon III encoding the second Sushi domain by Souri, M, Izumi, T, Higashi, Y, Girolami, A, Ichinose, A

“…We previously concluded that genetic defects in the B subunit of factor XIII were the basis for former Type I deficiency (i.e. factor XIII B subunit…”
Get more information

Example‐based face image super‐resolution taking into consideration correspondence of facial parts by Hamdan, Suhail, Fukumizu, Yohei, Izumi, Tomonori, Yamauchi, Hironori

“…Example‐based methods are widely adopted in image super‐resolution (SR) to generate clear, high‐resolution (HR) images from low‐resolution (LR) images. This…”
Get full text

Use of glucomannan for the separation of DNA fragments by capillary electrophoresis by Izumi, T, Yamaguchi, M, Yoneda, K, Isobe, T, Okuyama, T, Shinoda, T

“…Glucomannan, a natural polysaccharide extracted from Amorphophallus konjac, was employed as a sieving additive for the separation of restriction DNA fragments…”
Get more information

Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims: A pilot study by Oda, Yasutaka, Tsuruta, Ryosuke, Fujita, Motoki, Kaneda, Kotaro, Kawamura, Yoshikatsu, Izumi, Tomonori, Kasaoka, Shunji, Maruyama, Ikuro, Maekawa, Tsuyoshi

“…Abstract Objectives To investigate whether high mobility group box 1 (HMGB1) and S100B in cerebrospinal fluid (CSF) and the serum predict the neurological…”
Get full text

Requiem Protein Links RelB/p52 and the Brm-type SWI/SNF Complex in a Noncanonical NF-κB Pathway by Tando, Toshio, Ishizaka, Aya, Watanabe, Hirotaka, Ito, Taiji, Iida, Shun, Haraguchi, Takeshi, Mizutani, Taketoshi, Izumi, Tomonori, Isobe, Toshiaki, Akiyama, Taishin, Inoue, Jun-ichiro, Iba, Hideo

“…The SWI/SNF chromatin remodeling complex plays pivotal roles in mammalian transcriptional regulation. In this study, we identify the human requiem protein…”
Get full text

Mammalian phospholipase Cζ induces oocyte activation from the sperm perinuclear matrix by Fujimoto, Satoko, Yoshida, Naoko, Fukui, Tomoyuki, Amanai, Manami, Isobe, Toshiaki, Itagaki, Chiharu, Izumi, Tomonori, Perry, Anthony C.F.

“…Mammalian sperm-borne oocyte activating factor (SOAF) induces oocyte activation from a compartment that engages the oocyte cytoplasm, but it is not known how…”
Get full text