Search Results - "Izuhara, K."

Allergen immunotherapy for allergic asthma: A systematic review and meta‐analysis by Dhami, S., Kakourou, A., Asamoah, F., Agache, I., Lau, S., Jutel, M., Muraro, A., Roberts, G., Akdis, C. A., Bonini, M., Cavkaytar, O., Flood, B., Gajdanowicz, P., Izuhara, K., Kalayci, Ö., Mosges, R., Palomares, O., Pfaar, O., Smolinska, S., Sokolowska, M., Asaria, M., Netuveli, G., Zaman, H., Akhlaq, A., Sheikh, A.

“…Background To inform the development of the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines on Allergen Immunotherapy (AIT) for…”
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The IL‐13/periostin/IL‐24 pathway causes epidermal barrier dysfunction in allergic skin inflammation by Mitamura, Y., Nunomura, S., Nanri, Y., Ogawa, M., Yoshihara, T., Masuoka, M., Tsuji, G., Nakahara, T., Hashimoto‐Hachiya, A., Conway, S. J., Furue, M., Izuhara, K.

“…Background Barrier dysfunction is an important feature of atopic dermatitis (AD) in which IL‐4 and IL‐13, signature type 2 cytokines, are involved. Periostin,…”
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Prospective predictors of exacerbation status in severe asthma over a 3‐year follow‐up by Kimura, H., Konno, S., Makita, H., Taniguchi, N., Shimizu, K., Suzuki, M., Kimura, H., Goudarzi, H., Nakamaru, Y., Ono, J., Ohta, S., Izuhara, K., Ito, Y. M., Wenzel, S. E., Nishimura, M.

“…Summary Background A predisposition to exacerbations is being recognized as a distinct phenotype with “previous exacerbations” representing the strongest…”
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Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias by Okamoto, M, Hoshino, T, Kitasato, Y, Sakazaki, Y, Kawayama, T, Fujimoto, K, Ohshima, K, Shiraishi, H, Uchida, M, Ono, J, Ohta, S, Kato, S, Izuhara, K, Aizawa, H

“…Idiopathic interstitial pneumonias (IIPs) are histopathologically classified into several types, including usual interstitial pneumonia (UIP), nonspecific…”
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Serum periostin relates to type‐2 inflammation and lung function in asthma: Data from the large population‐based cohort Swedish GA(2)LEN by James, A., Janson, C., Malinovschi, A., Holweg, C., Alving, K., Ono, J., Ohta, S., Ek, A., Middelveld, R., Dahlén, B., Forsberg, B., Izuhara, K., Dahlén, S.‐E.

“…Background Periostin has been suggested as a novel, phenotype‐specific biomarker for asthma driven by type 2 inflammation. However, large studies examining…”
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Serum periostin levels are correlated with progressive skin sclerosis in patients with systemic sclerosis by Yamaguchi, Y., Ono, J., Masuoka, M., Ohta, S., Izuhara, K., Ikezawa, Z., Aihara, M., Takahashi, K.

“…Summary Background  Periostin, a matricellular protein, serves as a regulator of wound healing and fibrosis. The role of periostin in the pathogenesis of…”
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Utility of serum periostin and free IgE levels in evaluating responsiveness to omalizumab in patients with severe asthma by Tajiri, T., Matsumoto, H., Gon, Y., Ito, R., Hashimoto, S., Izuhara, K., Suzukawa, M., Ohta, K., Ono, J., Ohta, S., Ito, I., Oguma, T., Inoue, H., Iwata, T., Kanemitsu, Y., Nagasaki, T., Niimi, A., Mishima, M.

“…Background Omalizumab, a humanized anti‐IgE monoclonal antibody, has demonstrated efficacy in patients with severe allergic asthma. However, treatment…”
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Periostin levels correlate with disease severity and chronicity in patients with atopic dermatitis by Kou, K., Okawa, T., Yamaguchi, Y., Ono, J., Inoue, Y., Kohno, M., Matsukura, S., Kambara, T., Ohta, S., Izuhara, K., Aihara, M.

“…Summary Background Recent findings indicate that periostin, an extracellular matrix protein induced by T helper 2 cytokines, plays a critical role in the…”
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Elevation of serum squamous cell carcinoma antigen 2 in patients with psoriasis: associations with disease severity and response to the treatment by Watanabe, Y., Yamaguchi, Y., Komitsu, N., Ohta, S., Azuma, Y., Izuhara, K., Aihara, M.

“…Summary Background Squamous cell carcinoma antigen (SCCA) belongs to the ovalbumin–serpin family and is a known tumour marker. Expression of SCCA is…”
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IgE sensitization to food allergens and airborne allergens in relation to biomarkers of type 2 inflammation in asthma by Patelis, A., Alving, K., Middelveld, R., James, A., Ono, J., Ohta, S., Izuhara, K., Borres, M. P., Forsberg, B., Janson, C., Malinovschi, A.

“…Summary Background We have recently reported that sensitization to food allergens and sensitization to airborne allergens had independent associations with…”
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Reply to the Comment by Lobov et al. “Conformational rearrangements of plasminogen activator inhibitor type 2” by Izuhara, K.

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Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State by Askary, Amjad, Mork, Lindsey, Paul, Sandeep, He, Xinjun, Izuhara, Audrey K., Gopalakrishnan, Suhasni, Ichida, Justin K., McMahon, Andrew P., Dabizljevic, Sonja, Dale, Rodney, Mariani, Francesca V., Crump, J. Gage

“…An early event in skeletal joint development is the specification of articular chondrocytes at the joint surface. Articular chondrocytes are distinct in…”
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IL4Rα and ADAM33 as genetic markers in asthma exacerbations and type‐2 inflammatory endotype by Sunadome, H., Matsumoto, H., Petrova, G., Kanemitsu, Y., Tohda, Y., Horiguchi, T., Kita, H., Kuwabara, K., Tomii, K., Otsuka, K., Fujimura, M., Ohkura, N., Tomita, K., Yokoyama, A., Ohnishi, H., Nakano, Y., Oguma, T., Hozawa, S., Nagasaki, T., Ito, I., Oguma, T., Inoue, H., Tajiri, T., Iwata, T., Izuhara, Y., Ono, J., Ohta, S., Hirota, T., Tamari, M., Yokoyama, T., Niimi, A., Izuhara, K., Mishima, M.

“…Summary Background Genetic markers of susceptibility to asthma exacerbations in adults remain unclear. Objective To identify genetic markers of asthma…”
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Serum periostin levels associates to secondhand tobacco smoke exposure and exercise in children by Soon, Sung Myong, Suk, Lee Kyung, Yong, Han Man, Sung, Baek Hey, K, Izuhara

“…Methods This cross-sectional study examined 1,265 children from the general pediatric population who were first grade to sixth grade attended 6 elementary…”
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Serum periostin levels correlate with airway hyper‐responsiveness to methacholine and mannitol in children with asthma by Song, J.‐S., You, J.‐S., Jeong, S.‐I., Yang, S., Hwang, I.‐T., Im, Y.‐G., Baek, H.‐S., Kim, H.‐Y., Suh, D.‐I., Lee, H.‐B., Izuhara, K.

“…Background Periostin is a matricellular protein, and its synthesis in airway epithelial cells and lung fibroblasts is induced by interleukin (IL)‐4 and IL‐13…”
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Recent progress in understanding the diversity of the human ov-serpin/clade B serpin family by Izuhara, K, Ohta, S, Kanaji, S, Shiraishi, H, Arima, K

“…The inhibitory mechanism against proteases is important in the maintenance of homeostasis or health in the body. The human ovalbumin serpin (ovserpin)/ clade B…”
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Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution by Desposito, Dorinne, Schiessl, Ina Maria, Gyarmati, Georgina, Riquier-Brison, Anne, Izuhara, Audrey K, Kadoya, Hiroyuki, Der, Balint, Shroff, Urvi Nikhil, Hong, Young-Kwon, Peti-Peterdi, Janos

“…Endothelial cells are important in the maintenance of healthy blood vessels and in the development of vascular diseases. However, the origin and dynamics of…”
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Natural Large‐Scale Regeneration of Rib Cartilage in a Mouse Model by Srour, Marissa K, Fogel, Jennifer L, Yamaguchi, Kent T, Montgomery, Aaron P, Izuhara, Audrey K, Misakian, Aaron L, Lam, Stephanie, Lakeland, Daniel L, Urata, Mark M, Lee, Janice S, Mariani, Francesca V

“…ABSTRACT The clinical need for methods to repair and regenerate large cartilage and bone lesions persists. One way to make new headway is to study skeletal…”
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The mechanism of mucus production in bronchial asthma by Izuhara, K, Ohta, S, Shiraishi, H, Suzuki, S, Taniguchi, K, Toda, S, Tanabe, T, Yasuo, M, Kubo, K, Hoshino, T, Aizawa, H

“…Mucus production is a cardinal feature of bronchial asthma, contributing to morbidity and mortality in the disease. Goblet cells are major mucus-producing…”
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GLCCI1 variant accelerates pulmonary function decline in patients with asthma receiving inhaled corticosteroids by Izuhara, Y., Matsumoto, H., Kanemitsu, Y., Izuhara, K., Tohda, Y., Horiguchi, T., Kita, H., Kuwabara, K., Tomii, K., Otsuka, K., Fujimura, M., Ohkura, N., Tomita, K., Yokoyama, A., Ohnishi, H., Nakano, Y., Oguma, T., Hozawa, S., Nagasaki, T., Ito, I., Oguma, T., Inoue, H., Tajiri, T., Iwata, T., Ono, J., Ohta, S., Tamari, M., Hirota, T., Yokoyama, T., Niimi, A., Mishima, M.

“…Background In steroid‐naive patients with asthma, several gene variants are associated with a short‐term response to inhaled corticosteroid (ICS) treatment;…”
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