Adjunctive methylene blue antimicrobial photodynamic therapy for mucocutaneous lesions of mycoses: three case reports

Dermatophytosis, paracoccidioidomycosis and sporotrichosis are mycoses caused by different fungal species with significant prevalence in Brazil and other countries. In some situations, they affect quality of life, especially in the most vulnerable populations. Antifungal drug therapy is the conventi...

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Bibliographic Details
Published in:	Future microbiology Vol. 18; no. 15; pp. 1017 - 1024
Main Authors:	Izoton, Carlos FG, de Macedo, Priscila M, do Valle, Antonio CF, Almeida-Paes, Rodrigo, Figueiredo-Carvalho, Maria HG, Rabello, Vanessa BS, Martins, Ana CC, Freitas, Dayvison FS
Format:	Journal Article
Language:	English
Published:	Future Medicine Ltd 01-11-2023
Subjects:	antimicrobial photodynamic therapy dermatophytosis mucocutaneous lesions mycoses paracoccidioidomycosis sporotrichosis
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Summary:	Dermatophytosis, paracoccidioidomycosis and sporotrichosis are mycoses caused by different fungal species with significant prevalence in Brazil and other countries. In some situations, they affect quality of life, especially in the most vulnerable populations. Antifungal drug therapy is the conventional treatment for these diseases, although some difficulties may occur. Adjunctive use of antimicrobial photodynamic therapy (aPDT) may reduce these challenges. Three patients were treated with aPDT and conventional antifungals. In all cases, the patients did not report pain, discomfort or side effects during or after the aPDT intervention. The adjunctive use of aPDT in the cases presented proved to be a safe, low-cost tool that may be promising for the treatment of different mycoses. Some fungal diseases are very common in Brazil and other countries and, in some cases, treatment may be difficult. The combination of a type of laser may help the treatment of these diseases. Here, three cases of fungal diseases that were treated with laser, dye and conventional antifungals are presented.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1746-0913 1746-0921
DOI:	10.2217/fmb-2023-0074