Search Results - "Izco, María"
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Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian Pathology
Published in Molecular therapy (04-12-2019)“…The development of new therapies to slow down or halt the progression of Parkinson’s disease is a health care priority. A key pathological feature is the…”
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2
Oral Sub-chronic Ochratoxin A Exposure Induces Gut Microbiota Alterations in Mice
Published in Toxins (01-02-2021)“…Gut microbiota plays crucial roles in maintaining host health. External factors, such as diet, medicines, and environmental toxins, influence the composition…”
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3
Gut microbiota produces biofilm-associated amyloids with potential for neurodegeneration
Published in Nature communications (16-05-2024)“…Age-related neurodegenerative diseases involving amyloid aggregation remain one of the biggest challenges of modern medicine. Alterations in the…”
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4
Oral subchronic exposure to the mycotoxin ochratoxin A induces key pathological features of Parkinson's disease in mice six months after the end of the treatment
Published in Food and chemical toxicology (01-06-2021)“…Some epidemiological studies with different levels of evidence have pointed to a higher risk of Parkinson's disease (PD) after exposure to environmental…”
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Biomonitoring of Mycotoxins in Plasma of Patients with Alzheimer's and Parkinson's Disease
Published in Toxins (10-07-2021)“…Exposure to environmental contaminants might play an important role in neurodegenerative disease pathogenesis, such as Parkinson´s disease (PD) and Alzheimer´s…”
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6
Young foreign women in prison: A case study in Malaga prison
Published in Temida (2019)“…The aim of this paper is to present the results of the research on the reality that young migrant women face in prison, trying to analyze whether they, judging…”
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7
Wound Healing Modulation through the Local Application of Powder Collagen-Derived Treatments in an Excisional Cutaneous Murine Model
Published in Biomedicines (21-04-2022)“…Wound healing includes dynamic processes grouped into three overlapping phases: inflammatory, proliferative, and maturation/remodeling. Collagen is a critical…”
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8
Optimized protocol for amyloid-β extraction from the brain
Published in Journal of Alzheimer's disease (01-01-2013)“…Brain levels of amyloid-β (Aβ) are frequently assessed in transgenic mice models of Alzheimer's disease. The procedure involves tissue sample homogenization…”
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Outstanding Phenotypic Differences in the Profile of Amyloid-β between Tg2576 and APPswe/PS1dE9 Transgenic Mouse Models of Alzheimer's Disease
Published in Journal of Alzheimer's disease (03-08-2016)“…APPswe/PS1dE9 and Tg2576 are very common transgenic mouse models of Alzheimer's disease (AD), used in many laboratories as tools to research the mechanistic…”
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Análisis de las fuentes de datos estadísticos oficiales en materia de violencia de género en España
Published in Revista española de investigación criminológica (2021)“…El objetivo de la presente investigación descriptiva es determinar las principales fuentes de datos estadísticos en materia de violencia de género en España y…”
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11
Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain
Published in Psychopharmacology (01-01-2007)“…Ecstasy abuse commonly occurs in hot, overcrowded environments in combination with alcohol. Around 90% of ecstasy users take ethanol; over 70% of these users…”
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12
Impact of endolysosomal dysfunction upon exosomes in neurodegenerative diseases
Published in Neurobiology of disease (01-05-2022)“…Although the factors contributing to the pathogenesis of neurodegenerative diseases remain elusive, endolysosomal pathway is emerging as a key player in the…”
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Administration of neurotoxic doses of MDMA reduces sensitivity to ethanol and increases GAT-1 immunoreactivity in mice striatum
Published in Psychopharmacologia (2010)“…Rationale Mice with reduced dopamine activity following neurotoxic doses of 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) consume more ethanol (EtOH) and…”
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14
Glial activation precedes alpha-synuclein pathology in a mouse model of Parkinson’s disease
Published in Neuroscience research (01-09-2021)“…[Display omitted] •Microglial cell activation in SNpc precedes alpha-synuclein inclusion formation.•In striatum a significant astrogliosis was observed 90…”
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15
High-Performance Liquid Chromatography-Fluorescence Detection Method for Ochratoxin A Quantification in Small Mice Sample Volumes: Versatile Application across Diverse Matrices Relevant for Neurodegeneration Research
Published in Toxins (01-05-2024)“…Ochratoxin A (OTA) is a mycotoxin commonly found in various food products, which poses potential health risks to humans and animals. Recently, more attention…”
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Targeted Extracellular Vesicle Gene Therapy for Modulating Alpha-Synuclein Expression in Gut and Spinal Cord
Published in Pharmaceutics (01-04-2023)“…The development of effective disease-modifying therapies to halt Parkinson's disease (PD) progression is required. In a subtype of PD patients, alpha-synuclein…”
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17
Validation of capillary electrophoresis in the analysis of ewe's milk casein
Published in Journal of Chromatography A (05-02-1999)“…Recent investigations have shown that capillary electrophoresis (CE) can be an alternative to other techniques such as polyacrylamide gel electrophoresis…”
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Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") exhibit increased ethanol consumption and preference
Published in The Journal of pharmacology and experimental therapeutics (01-09-2007)“…MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") administration to mice produces relatively selective long-term neurotoxic damage to dopaminergic pathways…”
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The Two Faces of Exosomes in Parkinson’s Disease: From Pathology to Therapy
Published in The Neuroscientist (01-04-2022)“…Accumulating evidence suggests that exosomes play a key role in Parkinson’s disease (PD). Exosomes may contribute to the PD progression facilitating the spread…”
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Evaluation of the effect of rennet type on casein proteolysis in an ovine milk cheese by means of capillary electrophoresis
Published in Journal of Chromatography A (09-06-2000)“…Capillary electrophoresis was used to study the evolution of casein throughout the ripening process of Roncal Denomination of Origin ewe’s milk cheese and to…”
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