Search Results - "Izabel Campos Simplicio, Maria"
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Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19: The TOGETHER Randomized Clinical Trial
Published in JAMA network open (01-04-2021)“…Data on the efficacy of hydroxychloroquine or lopinavir-ritonavir for the treatment of high-risk outpatients with COVID-19 in developing countries are needed…”
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Effect of spirulina on risk of hospitalization among patients with COVID-19: the TOGETHER randomized trial
Published in The American journal of clinical nutrition (01-09-2024)“…Algae-derived nutraceuticals, such as spirulina, have been reported to have biological activities that may minimize clinical consequences to COVID-19…”
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Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trial
Published in Lancet Regional Health - Americas (Online) (01-02-2022)“…Observational studies have postulated a therapeutic role of metformin in treating COVID-19. We conducted an adaptive platform clinical trial to determine…”
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Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial
Published in The Lancet global health (01-01-2022)“…Recent evidence indicates a potential therapeutic role of fluvoxamine for COVID-19. In the TOGETHER trial for acutely symptomatic patients with COVID-19, we…”
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Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 : A Randomized Platform Trial
Published in Annals of internal medicine (01-05-2023)“…Previous trials have demonstrated the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with…”
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Matched vs Nonmatched Placebos in a Randomized Trial of COVID-19 Treatments
Published in JAMA network open (01-05-2024)“…Matched placebo interventions are complex and resource intensive. Recent evidence suggests matched placebos may not always be necessary. Previous studies have…”
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