Search Results - "Iyer, Vidhya V."

A Review of Stapled Peptides and Small Molecules to Inhibit Protein-Protein Interactions in Cancer by Iyer, Vidhya V

“…Disruption of binding of two or more molecules to a protein surface is a common basis of inhibition of many biological activities. Smallmolecule inhibitors,…”
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Small molecules for immunomodulation in cancer: a review by Iyer, Vidhya V

“…Small-molecule cytotoxic agents are already in use for cancer immunotherapy in the form of antibody conjugates containing these molecules linked covalently to…”
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Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells by Iyer, Vidhya V., Priya, P. Yoga, Kangeyavelu, Jeipreeti

“…Treatment with doxorubicin (dox) and emodin, separately and together, under normoxic and hypoxia-like conditions induced by CoCl 2 , led to greater…”
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Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions by Masaldan, Shashank, Iyer, Vidhya V.

“…ABSTRACT This study explores the link between the antiproliferative activity of emodin through the generation of reactive oxygen species (ROS) in various…”
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Differential growth inhibition of cancer cell lines and antioxidant activity of extracts of red, brown, and green marine algae by Murugan, Kavitha, Iyer, Vidhya V

“…As the use of various anticancer drugs is associated with many undesirable side effects, there is an urgent need for the discovery of new, better, and specific…”
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Antioxidant activity and gas chromatographic-mass spectrometric analysis of extracts of the marine algae, caulerpa peltata and padina gymnospora by Murugan, Kavitha, Iyer, Vidhya

“…The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising…”
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Antioxidant and Antiproliferative Activities of Extracts of Selected Red and Brown Seaweeds from the Mandapam Coast of Tamil Nadu by Murugan, Kavitha, Iyer, Vidhya V.

“…Antioxidant and antiproliferative activities were examined for methanol (M), chloroform (C), ethyl acetate (E) and aqueous (A) extracts of Turbinaria ornata,…”
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Pronucleotides: Toward the in vivo delivery of antiviral and anticancer nucleotides by Wagner, Carston R., Iyer, Vidhya V., McIntee, Edward J.

“…To overcome the many hurdles preventing the use of antiviral and anticancer nucleosides as therapeutics, the development of a prodrug methodology (i.e.,…”
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An Indian Perspective of Some Recent Developments in Polio, DPT, Zika and Rotavirus Vaccines by V. Iyer, Vidhya, Tejal, A, Poddar, A, Maithili, D, G. Rasika, L, Bendre, A, Jaswal, Vani

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The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation by Prutzman, Kirk C, Gao, Guanghua, King, Michelle L, Iyer, Vidhya V, Mueller, Geoffrey A, Schaller, Michael D, Campbell, Sharon L

“…The focal adhesion targeting (FAT) domain of focal adhesion kinase (FAK) is critical for recruitment of FAK to focal adhesions and contains tyrosine 926,…”
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Synthesis, in Vitro Anti-Breast Cancer Activity, and Intracellular Decomposition of Amino Acid Methyl Ester and Alkyl Amide Phosphoramidate Monoesters of 3‘-Azido-3‘-deoxythymidine (AZT) by Iyer, Vidhya V, Griesgraber, George W, Radmer, Matthew R, McIntee, Edward J, Wagner, Carston R

“…We report the synthesis and anticancer activity of a series of AZT phosphoramidate monoesters containing amino acid methyl ester (3a−11a) and N-alkyl amide…”
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CCAAT/enhancer-binding protein-β has a role in osteoblast proliferation and differentiation by Iyer, Vidhya V., Kadakia, Tejas B., McCabe, Laura R., Schwartz, Richard C.

“…CCAAT/enhancer binding protein β (C/EBPβ) is known to play an important role in the expression of several genes necessary for bone development and homeostasis…”
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Measurement of protein tyrosine phosphorylation in cell adhesion by Iyer, Vidhya V, Ballestrem, Christoph, Kirchner, Joachim, Geiger, Benjamin, Schaller, Michael D

“…This chapter describes biochemical, immunochemical, and microscopic approaches to measure protein tyrosine phosphorylation after cell adhesion. We have…”
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Inhibition of CMP-Sialic Acid Transport into Golgi Vesicles by Nucleoside Monophosphates by Chiaramonte, Molly, Koviach, Jennifer L, Moore, Chad, Iyer, Vidhya V, Wagner, Carston R, Halcomb, Randall L, Miller, Wayne, Melançon, Paul, Kuchta, Robert D

“…We examined the interactions of nucleotides with the CMP-sialic acid transporter in order to better understand which features play a role in binding and to…”
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Antioxidant and Antiproliferative Activities of Extracts of Selected Red and Brown Seaweeds from the Mandapam Coast of Tamil Nadu: Anticancer Activity of Red and Brown Seaweeds by Murugan, Kavitha, Iyer, Vidhya V.

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Tyrosine Phosphorylation of Type Iγ Phosphatidylinositol Phosphate Kinase by Src Regulates an Integrin-Talin Switch by Ling, Kun, Doughman, Renee L., Iyer, Vidhya V., Firestone, Ari J., Bairstow, Shawn F., Mosher, Deane F., Schaller, Michael D., Anderson, Richard A.

“…Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation of FAs is necessary for cells…”
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Embrace a Gift of Nature: A Proposal for Commercializing Natural Eco-Dyes for the Textile Industry by Iyer, Vidhya V

“…Textile dyes and the dyeing process are a significant, but often highly ignored, contributor to environmental pollution. This Article explores the nexus…”
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Tyrosine phosphorylation of type Igamma by Ling, Kun, Doughman, Renee L, Iyer, Vidhya V, Firestone, Ari J

“…Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation of FAs is necessary for cells…”
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Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch by Ling, Kun, Doughman, Renee L, Iyer, Vidhya V, Firestone, Ari J, Bairstow, Shawn F, Mosher, Deane F, Schaller, Michael D, Anderson, Richard A

“…Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation of FAs is necessary for cells…”
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Pronucleotides: Toward thein vivo delivery of antiviral and anticancer nucleotides by Wagner, Carston R., Iyer, Vidhya V., McIntee, Edward J.

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