Search Results - "Iyer, N G"

Mutational Signatures in Mandibular Ameloblastoma Correlate with Smoking by Guan, P., Wong, S.F., Lim, J.Q., Ng, C.C.Y., Soong, P.L., Sim, C.Q.X., Ong, C.K., Rajasegaran, V., Myint, S.S., Lee, J.Y., Tan, H.K., Iyer, N.G., Soo, K.C., Teh, B.T., Tay, A.B.G.

“…Ameloblastoma is a rare tumor of odontogenic epithelium, the low incidence rate of which precludes statistical determination of its molecular…”
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Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers by CHIN, S.-F, WANG, Y, IYER, N. G, KRANJAC, T, ROBERTSON, J. F. R, APARICIO, S, TAVARE, S, ELLIS, I, BRENTON, J. D, CALDAS, C, THORNE, N. P, TESCHENDORFF, A. E, PINDER, S. E, VIAS, M, NADERI, A, ROBERTS, I, BARBOSA-MORAIS, N. L, GARCIA, M. J

“…We analysed 148 primary breast cancers using BAC-arrays containing 287 clones representing cancer-related gene/loci to obtain genomic molecular portraits…”
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p300 is required for orderly G1 S transition in human cancer cells by IYER, N. G, XIAN, J, CHIN, S.-F, BANNISTER, A. J, DAIGO, Y, APARICIO, S, KOUZARIDES, T, CALDAS, C

“…The role of the transcriptional coactivator p300 in cell cycle control has not been analysed in detail due to the lack of appropriate experimental systems. We…”
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Thyroid incidentalomas: to treat or not to treat by Iyer, N. G., Shaha, Ashok R., Silver, Carl E., Devaney, Kenneth O., Rinaldo, Alessandra, Pellitteri, Phillip K., Ferlito, Alfio

“…Incidental lesions of the thyroid gland are an increasing problem facing clinicians. While asymptomatic palpable lesions are detected in only 4–7% of the…”
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Prognostic Performance of Current Stage III Oral Cancer Patients After Curative Intent Resection: Evidence to Support a Revision of the American Joint Committee on Cancer Staging System by Amit, M., Yen, T. C., Liao, C. T., Chaturvedi, P., Agarwal, J. P., Kowalski, L. P., Kohler, Hugo F., Ebrahimi, A., Clark, J. R., Cernea, C. R., Brandao, S. J., Kreppel, M., Zöller, J., Fliss, M. D., Bachar, G., Shpitzer, T., Bolzoni, V. A., Patel, P. R., Jonnalagadda, S., Robbins, K. T., Iyer, N. G., Skanthakumar, T., Shah, J. P., Patel, S. G., Gil, Z.

“…Background The American Joint Committee on Cancer (AJCC) stage III classification of oral cavity squamous cell carcinoma (OCSCC) represents a heterogeneous…”
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A simple and reliable pretreatment protocol facilitates fluorescent in situ hybridisation on tissue microarrays of paraffin wax embedded tumour samples by Chin, S-F, Daigo, Y, Huang, H-E, Iyer, N G, Callagy, G, Kranjac, T, Gonzalez, M, Sangan, T, Earl, H, Caldas, C

“…Aims: To describe a robust pretreatment protocol for preparing paraffin wax embedded tissues on tissue microarrays for fluorescence in situ hybridisation…”
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Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition by KRUBASIK, D, IYER, N. G, ENGLISH, W. R, AHMED, A. A, VIAS, M, ROSKELLEY, C, BRENTON, J. D, CALDAS, C, MURPHY, G

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Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours by ÖZDAG, H, BATLEY, S. J, FÖRSTI, A, LYER, N. G, DAIGO, Y, BOUTELL, J, ARENDS, M. J, PONDER, B. A. J, KOUZARIDES, T, CALDAS, C

“…In this study we screened the histone acetyltransferases CBP and PCAF for mutations in human epithelial cancer cell lines and primary tumours. We identified…”
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A chemical genetics approach to identify therapeutic vulnerabilities in Gefitinib resistant, EGFR T790M by Low, J., Koh, J.L.Y., Leong, H.S., Lau, D.P., Zhang, X., Kwang, X.L., Chan, J.V., Rikka, S., Tan, D S W, Periyasamy, G., Iyer, N.G., Dasgupta, R.

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Management of Thyroid Nodules and Surgery for Differentiated Thyroid Cancer by Iyer, N.G, Shaha, A.R

“…Abstract The incidence of well-differentiated thyroid cancer has seen a worldwide increase in the last three decades. Whether this is due to a ‘true increase’…”
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Kruppel-like factor 5 modulates p53-independent apoptosis through Pim1 survival kinase in cancer cells by Zhao, Y, Hamza, M S, Leong, H S, Lim, C-B, Pan, Y-F, Cheung, E, Soo, K-C, Iyer, N G

“…Although Kruppel-like factor 5 (KLF5) is a transcription factor that has been implicated in pathways critical to carcinogenesis, controversy persists as to…”
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Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition by Krubasik, D, Iyer, N G, English, W R, Ahmed, A A, Vias, M, Roskelley, C, Brenton, J D, Caldas, C, Murphy, G

“…p300 is a transcriptional cofactor and prototype histone acetyltransferase involved in regulating multiple cellular processes. We generated p300 deficient…”
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Ventilator-associated pneumonia by Visnegarwala, Fehmida, Iyer, Niranjan G., Hamill, Richard J.

“…Mechanically ventilated patients are at a substantially higher risk for developing nosocomial pneumonia. Overall, there is a relatively constant 1&!TN!150;3%…”
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Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition by Krubasik, D, Iyer, N G, English, W R, Ahmed, A A, Vias, M, Roskelley, C, Brenton, J D, Caldas, C, Murphy, G

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An Immune-Based Genomic Classifier (GC) Prognosticates for Survival in Endemic Nasopharyngeal Carcinoma by Chua, M.L.K., Sim, A.Y.L., Ong, E.H.W., Huang, L., Low, K.P., Tan, T.W.K., Fong, K.W., Lim, S.Y., Tan, G.S., Lim, T.K.H., Lim, D.W.T., Iyer, N.G., Wee, J., Hwang, J.S.G., Bei, J.X., Abazeed, M.

“…Nasopharyngeal carcinoma (NPC) is a distinct head and neck cancer that is associated with Epstein-Barr virus (EBV). Its histomorphology is characterized by…”
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On Handling Large-Scale Polynomial Multiplications in Compute Cloud Environments using Divisible Load Paradigm by Iyer, G. N., Veeravalli, B., Krishnamoorthy, S. G.

“…Large-scale polynomial product computations often used in aerospace applications such as satellite image processing and sensor networks data processing always…”
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Effectiveness of a Screening Tool for Early Identification of Malnutrition in Patients with Head and Neck Cancer by Chua, A., Turner, B. S., Iyer, N. G., Lim, S. F.

“…The purpose of this study was to evaluate the impact of the Malnutritional Universal Screening Tool (MUST) assessment on effects of postoperative surgical site…”
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Changing epidemiology of oral squamous cell carcinoma of the tongue: A global study by Ng, Jia Hui, Iyer, N. Gopalakrishna, Tan, Min‐Han, Edgren, Gustaf

“…ABSTRACT Background There are reports about the changing epidemiology of tongue squamous cell carcinoma (SCC), with recent reports indicating an increasing…”
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p300 CBP and cancer by Iyer, Narayanan Gopalakrishna, Ozdag, Hilal, Caldas, Carlos

“…p300 and cyclic AMP response element-binding protein (CBP) are adenoviral E1A-binding proteins involved in multiple cellular processes, and function as…”
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Pedunculated hepatic hemangioma: CT findings by Parikh, V P, Iyer, G N

“…Abstract only…”
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