Search Results - "Iyer, Mamta"

Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain by Rahighi, Simin, Iyer, Mamta, Oveisi, Hamid, Nasser, Sammy, Duong, Vincent

“…Ubiquitination of NEMO by the linear ubiquitin chain assembly complex (LUBAC) is essential for activating the canonical NF-κB signaling pathway. While the NZF1…”
Get full text

Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro by Hameedi, Mikhail A., T. Prates, Erica, Garvin, Michael R., Mathews, Irimpan I., Amos, B. Kirtley, Demerdash, Omar, Bechthold, Mark, Iyer, Mamta, Rahighi, Simin, Kneller, Daniel W., Kovalevsky, Andrey, Irle, Stephan, Vuong, Van-Quan, Mitchell, Julie C., Labbe, Audrey, Galanie, Stephanie, Wakatsuki, Soichi, Jacobson, Daniel

“…In addition to its essential role in viral polyprotein processing, the SARS-CoV-2 3C-like protease (3CLpro) can cleave human immune signaling proteins, like…”
Get full text

Structural insight on ubiquitination of NEMO for canonical activation of NF-κB by Iyer, Mamta, Rahighi, Simin

“…Abstract only…”
Get full text

Human volunteer, in vitro, and molecular level evaluation of an optimized taste-masked isoniazid-chitosan spray-dried microparticle matrix by Stagner, William C., Iyer, Mamta, Rathod, Vishal, Meruva, Saikishore, Staton, Scott, Haware, Rahul V.

“…[Display omitted] For the first time, isoniazid (INH) bitterness value, threshold, and sensitivity (low, moderate, high, and extremely high) was determined in…”
Get full text

Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis by Iyer, Janaki K, Kalra, Mamta, Kaul, Anil, Payton, Mark E, Kaul, Rashmi

“…AIM To investigate gender-specific liver estrogen receptor(ER) expression in normal subjects and patients with hepatitis C virus(HCV)-related cirrhosis and…”
Get full text

Caffeine Co-Crystal Mechanics Evaluated with a Combined Structural and Spectroscopic Approach by Singaraju, Aditya B, Iyer, Mamta, Haware, Rahul V, Stevens, Lewis L

“…In this report caffeine (CAF) co-crystallization with a fluoro-nitrobenzoic acid (F-NBA) yields a new solid form with superior tableting performance. A primary…”
Get full text