Search Results - "Iyengar, A. R. Satvik"

Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192 by Aggarwal, Geetika, Prajapati, Rameshwar, Tripathy, Rajan K, Bajaj, Priyanka, Iyengar, A R Satvik, Sangamwar, Abhay T, Pande, Abhay H

“…Human paraoxonase 1 (h-PON1) is a serum enzyme that can hydrolyze a variety of substrates. The enzyme exhibits anti-inflammatory, anti-oxidative,…”
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Protein Chimerization: A New Frontier for Engineering Protein Therapeutics with Improved Pharmacokinetics by Iyengar, A R Satvik, Gupta, Shreya, Jawalekar, Snehal, Pande, Abhay H

“…With the advancement of medicine, the utility of protein therapeutics is increasing exponentially. However, a significant number of protein therapeutics suffer…”
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Organophosphate-Hydrolyzing Enzymes as First-Line of Defence Against Nerve Agent-Poisoning: Perspectives and the Road Ahead by Iyengar, A. R. Satvik, Pande, Abhay H.

“…Nerve agents (NAs) are extremely neurotoxic synthetic organophosphate (OP) compounds exploited as weapons of mass destruction in terrorist attacks and chemical…”
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Improving storage stability of recombinant organophosphorus hydrolase by Satvik Iyengar, A.R., Tripathy, Rajan K., Bajaj, Priyanka, Pande, Abhay H.

“…•OPH can inactivate variety of organophosphate (OP)-compounds, including nerve agents.•OPH is a candidate for the development of therapeutic and…”
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Warfare Nerve Agents and Paraoxonase-1 as a Potential Prophylactic Therapy against Intoxication by Iyengar, A R Satvik, Khandave, Prakash Y, Bzdrenga, Janek, Nachon, Florian, Brazzolotto, Xavier, Pande, Abhay H

“…Nerve agents are a class of lethal neurotoxic chemicals used in chemical warfare. In this review, we have discussed a brief history of chemical warfare,…”
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