Search Results - "Iwaya, Hitoshi"

Alteration of Bile Acid Metabolism by a High-Fat Diet Is Associated with Plasma Transaminase Activities and Glucose Intolerance in Rats by YOSHITSUGU, Reika, KIKUCHI, Keidai, IWAYA, Hitoshi, FUJII, Nobuyuki, HORI, Shota, LEE, Dong Geun, ISHIZUKA, Satoshi

“…Ingestion of a high-fat (HF) diet is known to enhance bile acid (BA) secretion, but precise information about the BA molecular species is lacking, especially…”
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12α-Hydroxylated bile acid enhances accumulation of adiponectin and immunoglobulin A in the rat ileum by Yoshitsugu, Reika, Liu, Hongxia, Kamo, Yoshie, Takeuchi, Akari, Joe, Ga-Hyun, Tada, Koji, Kikuchi, Keidai, Fujii, Nobuyuki, Kitta, Shinri, Hori, Shota, Takatsuki, Manami, Iwaya, Hitoshi, Tanaka, Yasutake, Shimizu, Hidehisa, Ishizuka, Satoshi

“…We previously reported that dietary supplementation with cholic acid (CA), the primary 12α-hydroxylated (12αOH) bile acid (BA), reduces plasma adiponectin…”
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Correlation between 12α-hydroxylated bile acids and insulin secretion during glucose tolerance tests in rats fed a high-fat and high-sucrose diet by Yoshitsugu, Reika, Kikuchi, Keidai, Hori, Shota, Iwaya, Hitoshi, Hagio, Masahito, Shimizu, Hidehisa, Hira, Tohru, Ishizuka, Satoshi

“…Previously, we found a significant relationship in a rat study between energy intake and bile acid (BA) metabolism especially 12α-hydroxylated (12αOH) BAs. The…”
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Contribution of Dipeptidyl Peptidase IV to the Severity of Dextran Sulfate Sodium-Induced Colitis in the Early Phase by IWAYA, Hitoshi, FUJII, Nobuyuki, HAGIO, Masahito, HARA, Hiroshi, ISHIZUKA, Satoshi

“…Dipeptidyl peptidase IV (DPPIV) degrades some peptide hormones and cytokines, resulting in homeostatic modulation. However, the role of DPPIV in inflammatory…”
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Mucosal permeability is an intrinsic factor in susceptibility to dextran sulfate sodium-induced colitis in rats by Iwaya, Hitoshi, Maeta, Koushi, Hara, Hiroshi, Ishizuka, Satoshi

“…We investigated differences in the pathogenesis of dextran sulfate sodium (DSS)-induced colitis between two inbred rat strains, Wistar King A Hokkaido (WKAH)…”
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Deoxycholic Acid Is Involved in the Proliferation and Migration of Vascular Smooth Muscle Cells by SHIMIZU, Hidehisa, HAGIO, Masahito, IWAYA, Hitoshi, TSUNEKI, Ikuya, LEE, Ja-Young, FUKIYA, Satoru, YOKOTA, Atsushi, MIYAZAKI, Hitoshi, HARA, Hiroshi, ISHIZUKA, Satoshi

“…Obesity is increasingly becoming associated with increased risk of atherosclerosis. Serum levels of the bile acid deoxycholic acid (DCA) are elevated in mice…”
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Zinc deficiency induces dysregulation of cytokine productions in an experimental colitis of rats by Suwendi, Erwin, Iwaya, Hitoshi, Lee, Jae-Sung, Hara, Hiroshi, Ishizuka, Satoshi

“…Dextran sulfate sodium (DSS)-induced colitis is an experimental model of ulcerative colitis, although the precise mechanism has not yet been elucidated. We…”
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The delay in the development of experimental colitis from isomaltosyloligosaccharides in rats is dependent on the degree of polymerization by Iwaya, Hitoshi, Lee, Jae-Sung, Yamagishi, Shinya, Shinoki, Aki, Lang, Weeranuch, Thawornkuno, Charin, Kang, Hee-Kwon, Kumagai, Yuya, Suzuki, Shiho, Kitamura, Shinichi, Hara, Hiroshi, Okuyama, Masayuki, Mori, Haruhide, Kimura, Atsuo, Ishizuka, Satoshi

“…Isomaltosyloligosaccharides (IMO) and dextran (Dex) are hardly digestible in the small intestine and thus influence the luminal environment and affect the…”
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Acyl-homoserine lactones suppresses IEC-6 cell proliferation and increase permeability of isolated rat colon by Joe, Ga-Hyun, Andoh, Midori, Nomura, Mikako, Iwaya, Hitoshi, Lee, Jae-Sung, Shimizu, Hidehisa, Tsuji, Youhei, Maseda, Hideaki, Miyazaki, Hitoshi, Hara, Hiroshi, Ishizuka, Satoshi

“…We investigated to determine whether a variety of acyl-homoserine lactones (AHLs) influences epithelial cell proliferation and mucosal permeability. 3-Oxo-C 12…”
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P141 A LONG NONCODING RNA TRANSCRIBED FROM THE CD8 LOCUS CONTROLS FUNCTIONAL DIFFERENTIATION OF CD4 T CELLS IN THE INTESTINE by Iwaya, Hitoshi, Cheroutre, Hilde

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P141 A LONG NONCODING RNA TRANSCRIBED FROM THE CD8 LOCUS CONTROLS FUNCTIONAL DIFFERENTIATION OF CD4 T CELLS IN THE INTESTINE by Iwaya, Hitoshi, Cheroutre, Hilde

“…Abstract CD4 T cells adapt their immune function to the local tissue environment by differentiating into various functional subsets. At steady state,…”
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Small Intestine Epithelial CD4 Cytotoxic T Lymphocytes Provide Innate-Like Protection against Enteric Pathogens without Risk of Immunopathology by Chen, Angeline, Thiault, Nicolas, Iwaya, Hitoshi, Cheroutre, Hilde

“…Abstract CD4 T helper (Th) cells reprogram to cytotoxic T lymphocytes (CTLs) in the small intestinal epithelium. In the present study, CD4 CTLs were evaluated…”
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Dietary Antigens Drive Protective Innate-like CD4 T Cell Immunity at the Mucosal Barrier of the Small Intestine by Chen, Angeline, Thiault, Nicolas, Verstichel, Greet, Iwaya, Hitoshi, Cheroutre, Hilde

“…Abstract CD4 T helper (Th) cells reprogram to cytotoxic T lymphocytes (CTLs) in the intestinal epithelium during steady state. The unique localization of…”
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Small Intestinal Cytotoxic CD4 T Cells: Novel Mechanisms of Development and Unique Protective Capability by Chen, Angeline, Iwaya, Hitoshi, Thiault, Nicolas, Cheroutre, Hilde

“…Abstract Conventional CD4 T helper T cells convert to CD4 cytotoxic T lymphocytes (CTL) in the small intestinal epithelium during steady state, but the…”
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The Cd8 locus Controls the Functional Conversion of CD4 Th cells to CD4 CTL in the Intestine by Iwaya, Hitoshi, Larange, Alexandre, Kakugawa, Kiyokazu, Cheroutre, Hilde

“…Abstract CD4 T cells adapt to their surroundings by differentiating into various T helper (Th) subsets. At steady state, regulatory CD4 T cells (Treg) and…”
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Natural ThPOK− CD4 cytotoxic T lymphocytes : Thymic development of a new distinct self-specific CD4 T cell population by Thiault, Nicolas, Mushtaq, Mohd.Husain, Iwaya, Hitoshi, Verstichel, Greet, Cheroutre, Hilde

“…Abstract The lineage commitment to either CD4 or CD8 T cells is made in the thymus, where thymocytes with specificity for MHC-II molecules differentiates into…”
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TCR signal strength shapes functional imprinting during CD4 T cell development by Verstichel, Greet, Thiault, Nicolas, Kakugawa, Kiyokazu, Chen, Angeline, Iwaya, Hitoshi, Takazawa, Ikuo, Cheroutre, Hilde

“…Abstract Naïve CD4 and CD8ab T cells are selected in the thymus in response to low-avidity TCR interactions. Such weak TCR signals install a quiescent program…”
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A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function by Larange, Alexandre, Takazawa, Ikuo, Kakugawa, Kiyokazu, Thiault, Nicolas, Ngoi, SooMun, Olive, Meagan E., Iwaya, Hitoshi, Seguin, Laetitia, Vicente-Suarez, Ildefonso, Becart, Stephane, Verstichel, Greet, Balancio, Ann, Altman, Amnon, Chang, John T., Taniuchi, Ichiro, Lillemeier, Bjorn, Kronenberg, Mitchell, Myers, Samuel A., Cheroutre, Hilde

“…Ligation of retinoic acid receptor alpha (RARα) by RA promotes varied transcriptional programs associated with immune activation and tolerance, but genetic…”
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12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats by Lee, Ja-Young, Shimizu, Hidehisa, Hagio, Masahito, Fukiya, Satoru, Watanabe, Masamichi, Tanaka, Yasutake, Joe, Ga-Hyun, Iwaya, Hitoshi, Yoshitsugu, Reika, Kikuchi, Keidai, Tsuji, Misaki, Baba, Nanako, Nose, Takuma, Tada, Koji, Hanai, Taketo, Hori, Shota, Takeuchi, Akari, Furukawa, Yumiko, Shirouchi, Bungo, Sato, Masao, Ooka, Tadasuke, Ogura, Yoshitoshi, Hayashi, Tetsuya, Yokota, Atsushi, Ishizuka, Satoshi

“…There is an increasing need to explore the mechanism of the progression of non-alcoholic fatty liver disease. Steroid metabolism is closely linked to hepatic…”
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Peripheral Reprogrammed CD4+ CTL Efficiently Control Tumor Growth by Thiault, Nicolas, Husain, Mushtaq, Iwaya, Hitoshi, Cheroutre, Hilde

“…Abstract The initial commitment to either the CTL- or Th-lineage is made during thymic development, where thymocytes expressing an MHC class II–reactive TCR…”
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