Search Results - "Iwatsuru, M"

Liposomes bearing polyethyleneglycol-coupled transferrin with intracellular targeting property to the solid tumors in vivo by ISHIDA, Osamu, MARUYAMA, Kazuo, TANAHASHI, Hiroyuki, IWATSURU, Motoharu, SASAKI, Katsunori, ERIGUCHI, Masazumi, YANAGIE, Hironobu

“…The purpose of this study was to determine the usefulness of transferrin (TF)-pendant-type polyethyleneglycol (PEG)-liposomes (TF-PEG-liposomes), in which TF…”
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Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice by Ishida, Osamu, Maruyama, Kazuo, Sasaki, Katsunori, Iwatsuru, Motoharu

“…We have examined the size dependence of extravasation and interstitial localization of polyethyleneglycol-coated liposomes (PEG-liposomes) in the solid tumor…”
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Glucocorticoid-induced cataract in chick embryo monitored by Raman spectroscopy by MIZUNO, A, NISHIGORI, H, IWATSURU, M

“…Glucocorticoid-induced cataract lens in chick embryo was monitored by laser Raman spectroscopy. The lens opacity that appeared in chick embryo is a reversible…”
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Immunoliposomes bearing polyethyleneglycol-coupled Fab′ fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo by Maruyama, Kazuo, Takahashi, Nobuya, Tagawa, Toshiaki, Nagaike, Kazuhiro, Iwatsuru, Motoharu

“…We have developed a new type of long-circulating immunoliposome (Fab′–PEG immunoliposomes) which is efficiently extravasated into the targeted solid tumor in…”
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Analysis of glucose levels during glucocorticoid-induced cataract formation in chick embryos by NISHIGORI, H, LEE, J. W, YAMAUCHI, Y, MARUYAMA, K, IWATSURU, M

“…When 15-day-old developing chick embryos were administered hydrocortisone hemisuccinate sodium (HC; 0.25 mumol/egg), the content of glucose in the lens…”
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Effect of MPG on glucocorticoid-induced cataract formation in developing chick embryo by NISHIGORI, H, HAYASHI, R, LEE, J. W, IWATSURU, M

“…Cataract in the developing chick embryo can be easily produced by administration of high doses of glucocorticoid and the cataract is preceded by a decreased…”
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Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies by Maruyama, Kazuo, Takizawa, Tomoko, Yuda, Tsutomu, Kennel, Stephen J, Huang, Leaf, Iwatsuru, Motoharu

“…Distearoyl- N-(3-carboxypropionoyl poly(ethylene glycol) succinyl)phosphatidylethanolamine (DSPE-PEG-COOH) was newly synthesized and used to prepare novel…”
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Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy by Unezaki, Sakae, Maruyama, Kazuo, Hosoda, Jun-Ichi, Nagae, Itsuro, Koyanagi, Yasuhisa, Nakata, Mikiho, Ishida, Osamu, Iwatsuru, Motoharu, Tsuchiya, Seishi

“…The extravasation of liposomes of different sizes into solid tumors after i.v. injection was visualized by in vivo fluorescence microscopy in mouse…”
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Encapsulation characteristics of nystatin in liposomes: effects of cholesterol and polyethylene glycol derivatives by Moribe, Kunikazu, Maruyama, Kazuo, Iwatsuru, Motoharu

“…In this study, we characterized the encapsulation of amphipathic nystatin into liposomes with or without cholesterol (CH) and a polyethylene glycol derivative,…”
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Targetability and intracellular delivery of anti-BCG antibody-modified, pH-sensitive fusogenic immunoliposomes to tumor cells by Mizoue, Toshiro, Horibe, Toshiya, Maruyama, Kazuo, Takizawa, Tomoko, Iwatsuru, Motoharu, Kono, Kenji, Yanagie, Hironobu, Moriyasu, Fuminori

“…We prepared tumor-specific immunoliposomes by coupling anti-BCG monoclonal antibodies to pH-sensitive fusogenic liposomes modified with succinylated…”
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Molecular localization and state of amphotericin B in PEG liposomes by Moribe, Kunikazu, Maruyama, Kazuo, Iwatsuru, Motoharu

“…We investigated the molecular localization and state of amphotericin B (AmB) encapsulated in polyethylene glycol (PEG)-coated liposomes. AmB-encapsulating…”
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Enhanced delivery of doxorubicin to tumor by long-circulating thermosensitive liposomes and local hyperthermia by Maruyama, K, Unezaki, S, Takahashi, N, Iwatsuru, M

“…Doxorubicin (DXR) was encapsulated in long-circulating, thermosensitive liposomes (180-200 nm), prepared from dipalmitoylphosphatidylcholine…”
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Enhanced delivery and antitumor activity of doxorubicin using long-circulating thermosensitive liposomes containing amphipathic polyethylene glycol in combination with local hyperthermia by UNEZAKI, S, MARUYAMA, K, TAKAHASHI, N, KOYAMA, M, YUDA, T, SUGINAKA, A, IWATSURU, M

“…Enhanced delivery of doxorubicin (DXR) to a solid tumor subjected to local hyperthermia was achieved by using long-circulating, thermosensitive liposomes (TSL)…”
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Measurements of Bovine Serum Albumin·Acid Violet 6B Binding by Dual-Wavelength Spectrophotometry by SEKIGUCHI, KEIJI, IWATSURU, MOTOHARU

“…The dual-wavelength spectrophotometer was employed to determine the protein-binding quantity between bovine serum albumin (BSA) and Acid Violet 6B (AV, C.I…”
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Spectroscopic investigation of the molecular state of nystatin encapsulated in liposomes by Moribe, Kunikazu, Maruyama, Kazuo, Iwatsuru, Motoharu

“…The stability and spectral properties of nystatin-encapsulating liposomes, composed of various combinations of dipalmitoyl phosphatidylcholine (DPPC),…”
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Targeting Chemotherapy to Solid Tumors with Long‐circulating Thermosensitive Liposomes and Local Hyperthermia by Ishida, Osamu, Maruyama, Kazuo, Yanagie, Hironobu, Eriguchi, Masazumi, Iwatsuru, Motoharu

“…The effectiveness of the combination of long‐circulating, thermosensitive liposomes and hyperthermia is described. Small‐sized, thermosensitive liposomes that…”
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Targeting efficiency of PEG-immunoliposome-conjugated antibodies at PEG terminals by Maruyama, Kazuo, Takizawa, Tomoko, Takahashi, Nobuya, Tagawa, Toshiaki, Nagaike, Kazuhiro, Iwatsuru, Motoharu

“…We have developed a new type of PEG-immunoliposome carrying monoclonal antibodies or their fragments (F(ab′)2, Fab′) at the distal ends of the PEG chains (Type…”
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Inference of Secondary Binding Spectrum of Naphthol Yellow S with Bovine Serum Albumin by IWATSURU, MOTOHARU, SEKIGUCHI, KEIJI

“…The protein binding of Naphthol Yellow S to bovine serum albumin (BSA) was examined and three pairs of parameters (binding numbers and constants) were obtained…”
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Enhanced encapsulation of amphotericin B into liposomes by complex formation with polyethylene glycol derivatives by MORIBE, K, TANAKA, E, MARUYAMA, K, IWATSURA, M

“…A highly efficient method was developed for the encapsulation of amphotericin B (AmB) in liposomes, and the mechanism involved was characterized. AmB was…”
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Elevation of blood lipid peroxide (TBA-reacting substance) level in developing chick embryos after glucocorticoid administration by Nishigori, H, Lee, J W, Yamauchi, Y, Iwatsuru, M

“…When 15-day-old chick embryos were administered 0.25 mumol of hydrocortisone hemisuccinate sodium (HC) the lipid peroxides (LPO) level increased after a lag…”
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