Search Results - "Iwasaki, Arihiro"
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Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae
Published in Journal of the American Chemical Society (22-06-2022)“…Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) is a membrane protein on the endoplasmic reticulum (ER) that transports Ca2+ from the cytosol into the ER. As…”
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Marine Natural Products: A Source of Novel Anticancer Drugs
Published in Marine drugs (23-08-2019)“…Cancer remains one of the most lethal diseases worldwide. There is an urgent need for new drugs with novel modes of action and thus considerable research has…”
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Isolation and Total Synthesis of Beru’amide, an Antitrypanosomal Polyketide from a Marine Cyanobacterium Okeania sp
Published in Organic letters (01-07-2022)“…A 68 μg amount of an acyclic polyketide, named beru’amide, was isolated from a marine cyanobacterium Okeania sp. Beru’amide contains six unique moieties in its…”
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4
Isolation of Hennaminal and Isolation and Total Synthesis of Hennamide, Pyrrolinone Compounds from the Marine Cyanobacterium Rivularia sp
Published in Organic letters (14-04-2023)“…Two new natural products were isolated from the marine cyanobacterium Rivularia sp. collected in Japan. Hennaminal possesses a very rare functional group,…”
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Isolation and Total Synthesis of Kinenzoline, an Antitrypanosomal Linear Depsipeptide Isolated from a Marine Salileptolyngbya sp. Cyanobacterium
Published in Journal of organic chemistry (17-09-2021)“…Kinenzoline (1), a new linear depsipeptide, was isolated from a marine Salileptolyngbya sp. cyanobacterium. Its structure was elucidated by spectroscopic…”
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Total Synthesis of Caldorazole, a Potent Mitochondrial Respiratory Chain Inhibitor without Chiral Centers
Published in Journal of organic chemistry (03-03-2023)“…Caldorazole (1) is a novel polyketide that was isolated from a marine cyanobacterium in 2022. It is a unique natural product that exhibits potent inhibitory…”
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Isolation and Total Synthesis of Bromoiesol sulfates, Antitrypanosomal arylethers from a Salileptolyngbya sp. Marine Cyanobacterium
Published in Journal of organic chemistry (03-09-2021)“…Bromoiesol sulfates A (1) and B (2), new polyhalogenated aryl sulfates, were isolated from a Salileptolyngbya sp. marine cyanobacterium along with their…”
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Motobamide, an Antitrypanosomal Cyclic Peptide from a Leptolyngbya sp. Marine Cyanobacterium
Published in Journal of natural products (Washington, D.C.) (28-05-2021)“…Motobamide (1), a new cyclic peptide containing a C-prenylated cyclotryptophan residue, was isolated from a marine Leptolyngbya sp. cyanobacterium. Its planar…”
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Isolation and structure determination of a new analog of polycavernosides from marine Okeania sp. cyanobacterium
Published in Beilstein journal of organic chemistry (21-03-2024)“…Polycavernoside E ( ), a new polycavernoside analog, was isolated from a marine sp. cyanobacterium. The relative configuration was elucidated primarily by…”
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Total Synthesis, Stereochemical Revision, and Biological Assessment of Iriomoteolide‐2a
Published in Chemistry : a European journal (26-06-2019)“…Iriomoteolide‐2a is a marine macrolide metabolite isolated from a cultured broth of the benthic dinoflagellate Amphidinium sp. HYA024 strain. This naturally…”
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Total Synthesis of Kanamienamide and Clarification of Biological Activity
Published in Journal of organic chemistry (01-12-2017)“…The total synthesis of kanamienamide, an enamide with an enol ether and an 11-membered macrolactone of marine origin, was achieved. The synthesis features the…”
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Amantamide C, an Antitrypanosomal Linear Lipopeptide from a Marine Okeania sp. Cyanobacterium
Published in ACS omega (27-08-2024)“…Amantamides are lipopeptides that act as selective CXC chemokine receptor 7 agonists and modulate spontaneous calcium oscillations in primary cultured…”
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Isolation and Structure of Kurahyne B and Total Synthesis of the Kurahynes
Published in Journal of natural products (Washington, D.C.) (25-11-2015)“…Kurahyne B (2), a new analogue of kurahyne (1), was isolated from the marine cyanobacterium Okeania sp. Its gross structure was elucidated based on…”
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Allelopathic Activity of Leaf Wastes of Liriodendron tulipifera for Sustainable Management
Published in Applied sciences (01-09-2024)“…Logging operations of Liriodendron tulipifera L., as timber trees, and fallen leaves in autumn from ornamental trees produce a large amount of leaf waste. In…”
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Isolation, Structure Determination, and Total Synthesis of Hoshinoamide C, an Antiparasitic Lipopeptide from the Marine Cyanobacterium Caldora penicillata
Published in Journal of natural products (Washington, D.C.) (22-01-2021)“…Hoshinoamide C (1), an antiparasitic lipopeptide, was isolated from the marine cyanobacterium Caldora penicillata. Its planar structure was elucidated by…”
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First Total Synthesis and Structure–Activity Relationship of Iheyamide A, an Antitrypanosomal Linear Peptide Isolated from a Dapis sp. Marine Cyanobacterium
Published in Journal of natural products (Washington, D.C.) (24-09-2021)“…Iheyamide A (1) is an antitrypanosomal linear peptide isolated from a Dapis sp. marine cyanobacterium by our group in 2020, and based on structure–activity…”
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Isolation and Total Synthesis of Hoshinolactam, an Antitrypanosomal Lactam from a Marine Cyanobacterium
Published in Organic letters (17-02-2017)“…In the search for new antiprotozoal substances, hoshinolactam, an antitrypanosomal lactam, was isolated from a marine cyanobacterium. The gross structure was…”
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Allelopathy and Allelochemicals in Chamaecyparis obtusa Leaves for the Development of Sustainable Agriculture
Published in Agronomy (Basel) (01-07-2024)“…Chamaecyparis obtusa (Siebold et Zucc.) Endl. is cultivated in the temperate region of East Asia for its high-quality and profitable timber. The…”
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Total synthesis and stereochemical determination of yoshinone A
Published in Phytochemistry (Oxford) (01-12-2016)“…In 2014, the γ-pyrone-containing polyketide, yoshinone A, was isolated from the marine cyanobacterium Leptolyngbya sp. and its structure was determined…”
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Minnamide A, a Linear Lipopeptide from the Marine Cyanobacterium Okeania hirsuta
Published in Organic letters (15-02-2019)“…Minnamide A is a lipopeptide with a unique repeating structure consisting of hydroxy and proposed β-branched methyl groups. The absolute configuration of…”
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