Search Results - "Iwanari, H"

Expression of pentraxin 3 (PTX3) in human atherosclerotic lesions by Savchenko, AS, Imamura, M, Ohashi, R, Jiang, S, Kawasaki, T, Hasegawa, G, Emura, I, Iwanari, H, Sagara, M, Tanaka, T, Hamakubo, T, Kodama, T, Naito, M

“…Pentraxin 3 (PTX3) and C-reactive protein (CRP) are members of the pentraxin superfamily. PTX3 expression is induced in response to inflammatory signals, and…”
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Neutralization of the γ-secretase activity by monoclonal antibody against extracellular domain of nicastrin by Hayashi, I, Takatori, S, Urano, Y, Miyake, Y, Takagi, J, Sakata-Yanagimoto, M, Iwanari, H, Osawa, S, Morohashi, Y, Li, T, Wong, P C, Chiba, S, Kodama, T, Hamakubo, T, Tomita, T, Iwatsubo, T

“…Several lines of evidence suggest that aberrant Notch signaling contributes to the development of several types of cancer. Activation of Notch receptor is…”
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Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4α in the pathogenesis of human cancer by Tanaka, T, Jiang, S, Hotta, H, Takano, K, Iwanari, H, Sumi, K, Daigo, K, Ohashi, R, Sugai, M, Ikegame, C, Umezu, H, Hirayama, Y, Midorikawa, Y, Hippo, Y, Watanabe, A, Uchiyama, Y, Hasegawa, G, Reid, PC, Aburatani, H, Hamakubo, T, Sakai, J, Naito, M, Kodama, T

“…Hepatocyte nuclear factor‐4α (HNF4α) exists in multiple isoforms that are generated by alternative promoter (P1 and P2) usage and splicing. Here we establish…”
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Aldo-keto reductase family 1, member B10 in uterine carcinomas: a potential risk factor of recurrence after surgical therapy in cervical cancer by Yoshitake, H, Takahashi, M, Ishikawa, H, Nojima, M, Iwanari, H, Watanabe, A, Aburatani, H, Yoshida, K, Ishi, K, Takamori, K, Ogawa, H, Hamakubo, T, Kodama, T, Araki, Y

“…Aldo-keto reductase family 1, member B10 (AKR1B10), an enzyme that converts retinals into retinols is known to detect in non-small cell lung carcinoma…”
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P11-6 Navigation-guided repetitive transcranial magnetic stimulation (rTMS) applied to major depression and rTMS-induced increase of gray matter volume by Nakamura, M, Noda, Y, Saeki, T, Kawamoto, E, Yamamoto, Y, Iwama, H, Iwanari, H, Hirayasu, Y

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Significance of circulating hepatocyte growth factor level as a prognostic indicator in primary breast cancer by TOI, M, TANIGUCHI, T, UENO, T, ASANO, M, FUNATA, N, SEKIGUCHI, K, IWANARI, H, TOMINAGA, T

“…The circulating hepatocyte growth factor (HGF)/scatter factor level is frequently increased in advanced cancer patients. In this study, we have assessed the…”
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Hyoscyamine 6 beta-hydroxylase, an enzyme involved in tropane alkaloid biosynthesis, is localized at the pericycle of the root by Hashimoto, T. (Kyoto University, Kyoto, Japan), Hayashi, A, Amano, Y, Kohno, J, Iwanari, H, Usuda, S, Yamada, Y

“…Hyoscyamine 6 beta-hydroxylase (H6H; EC 1.14.11.11) catalyzes the first reaction in the biosynthetic pathway from hyoscyamine to scopolamine in several…”
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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9 by Tachibana, Makoto, Ueda, Jun, Fukuda, Mikiko, Takeda, Naoki, Ohta, Tsutomu, Iwanari, Hiroko, Sakihama, Toshiko, Kodama, Tatsuhiko, Hamakubo, Takao, Shinkai, Yoichi

“…Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic mark for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that…”
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The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma by Yamauchi, Naoko, Watanabe, Akira, Hishinuma, Michiyo, Ohashi, Ken-ichi, Midorikawa, Yutaka, Morishita, Yasuyuki, Niki, Toshiro, Shibahara, Junji, Mori, Masaya, Makuuchi, Masatoshi, Hippo, Yoshitaka, Kodama, Tatsuhiko, Iwanari, Hiroko, Aburatani, Hiroyuki, Fukayama, Masashi

“…Expression profiling of hepatocellular carcinoma has demonstrated that glypican 3 (GPC3), a heparan sulfate proteoglycan anchored to the membrane, is expressed…”
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Overexpression of the Aldo-Keto Reductase Family Protein AKR1B10 Is Highly Correlated with Smokers' Non–Small Cell Lung Carcinomas by FUKUMOTO, Shin-Ichi, YAMAUCHI, Naoko, IWANARI, Hiroko, HIRONAKA, Mitsugu, ISHIKAWA, Yuichi, NIKI, Toshiro, SOHARA, Yasunori, KODAMA, Tatsuhiko, NISHIMURA, Masaharu, FUKAYAMA, Masashi, DOSAKA-AKITA, Hirotoshi, ABURATANI, Hiroyuki, MORIGUCHI, Hisashi, HIPPO, Yoshitaka, WATANABE, Akira, SHIBAHARA, Junji, TANIGUCHI, Hirokazu, ISHIKAWA, Shumpei, ITO, Hirotaka, YAMAMOTO, Shogo

“…Purpose: Squamous cell carcinoma (SCC) and adenocarcinoma of the lung are currently subject to similar treatment regimens despite distinct differences in…”
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Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma by HIPPO, Yoshitaka, WATANABE, Kiyotaka, NEZU, Jun-Ichi, TSUNODA, Hiroyuki, YOSHINO, Takeshi, OHIZUMI, Iwao, TSUCHIYA, Masayuki, OHNISHI, Shin, MAKUUCHI, Masatoshi, HAMAKUBO, Takao, KODAMA, Tatsuhiko, ABURATANI, Hiroyuki, WATANABE, Akira, MIDORIKAWA, Yutaka, YAMAMOTO, Shogo, IHARA, Sigeo, TOKITA, Susumu, IWANARI, Hiroko, ITO, Yukio, NAKANO, Kiyotaka

“…For detection of hepatocellular carcinoma (HCC) in patients with liver cirrhosis, serum alpha-fetoprotein has been widely used, but its sensitivity has not…”
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Glypican‐3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP‐7 signaling by Midorikawa, Yutaka, Ishikawa, Shumpei, Iwanari, Hiroko, Imamura, Takeshi, Sakamoto, Hirohiko, Miyazono, Kohei, Kodama, Tatsuhiko, Makuuchi, Masatoshi, Aburatani, Hiroyuki

“…The Glypican (GPC) family is a prototypical member of the cell‐surface heparan sulfate proteoglycans (HSPGs). The HSPGs have been demonstrated to interact with…”
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Serological detection of hepatitis B virus genotypes by ELISA with monoclonal antibodies to type-specific epitopes in the preS2-region product by Usuda, Sadakazu, Okamoto, Hiroaki, Iwanari, Hiroko, Baba, Kiyoshi, Tsuda, Fumio, Miyakawa, Yuzo, Mayumi, Makoto

“…An ELISA was developed for serological determination of the six genotypes of hepatitis B virus (HBV) designated A, B, C, D, E, and F. Monoclonal antibodies…”
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An opposing view on WWOX protein function as a tumor suppressor by WATANABE, Akira, HIPPO, Yoshitaka, TANIGUCHI, Hirokazu, IWANARI, Hiroko, YASHIRO, Masakazu, HIRAKAWA, Kosei, KODAMA, Tatsuhiko, ABURATANI, Hiroyuki

“…WW domain-containing oxidoreductase (WWOX) is a candidate tumor suppressor gene. Because mutation or deletion in the coding region of WWOX is rarely found, it…”
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Neutralization of the [gamma]-secretase activity by monoclonal antibody against extracellular domain of nicastrin by Hayashi, I, Takatori, S, Urano, Y, Miyake, Y, Takagi, J, Sakata-yanagimoto, M, Iwanari, H, Osawa, S, Morohashi, Y, Li, T, Wong, P C, Chiba, S, Kodama, T, Hamakubo, T, Tomita, T, Iwatsubo, T

“…Several lines of evidence suggest that aberrant Notch signaling contributes to the development of several types of cancer. Activation of Notch receptor is…”
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Establishment of Rat Dermal Papilla Cell Lines that Sustain the Potency to Induce Hair Follicles from Afollicular Skin by Inamatsu, Mutsumi, Matsuzaki, Takashi, Iwanari, Hiroko, Yoshizato, Katsutoshi

“…Dermal papilla cells in culture show a lower proliferative capacity compared with dermal fibroblasts, and lose their in situ potency to induce hair follicles…”
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Hepatocyte growth factor in the sera of patients with gastrointestinal and breast cancer by Narita, T, Toi, M, Sekiguchi, K, Iwanari, H, Matsuura, N, Kimura, N, Mitsuoka, C, Kannagi, R

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Overexpression of MUC13 is associated with intestinal‐type gastric cancer by Shimamura, Takahiro, Ito, Hirotaka, Shibahara, Junji, Watanabe, Akira, Hippo, Yoshitaka, Taniguchi, Hirokazu, Chen, Yongxin, Kashima, Takeshi, Ohtomo, Toshihiko, Tanioka, Fumihiko, Iwanari, Hiroko, Kodama, Tatsuhiko, Kazui, Teruhisa, Sugimura, Haruhiko, Fukayama, Masashi, Aburatani, Hiroyuki

“…Mucins are secreted or transmembrane glycoproteins that are expressed mainly in the digestive tract. This family of proteins has been the focus of much gastric…”
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Prominent expression of FRS2β protein in neural cells and its association with intracellular vesicles by Minegishi, Yuriko, Iwanari, Hiroko, Mochizuki, Yasuhiro, Horii, Takako, Hoshino, Tomoko, Kodama, Tatsuhiko, Hamakubo, Takao, Gotoh, Noriko

“…The fibroblast growth factor receptor substrate (FRS)-2 protein family comprises FRS2α, a well-known central mediator for fibroblast growth factor signaling,…”
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Viral envelope protein gp64 transgenic mouse facilitates the generation of monoclonal antibodies against exogenous membrane proteins displayed on baculovirus by Saitoh, Ryoichi, Ohtomo, Toshihiko, Yamada, Yoshiki, Kamada, Nobuo, Nezu, Jun-ichi, Kimura, Naoki, Funahashi, Shin-ichi, Furugaki, Koh, Yoshino, Takeshi, Kawase, Yosuke, Kato, Atsuhiko, Ueda, Otoya, Jishage, Kou-ichi, Suzuki, Masami, Fukuda, Rie, Arai, Masahiro, Iwanari, Hiroko, Takahashi, Kazuaki, Sakihama, Toshiko, Ohizumi, Iwao, Kodama, Tatsuhiko, Tsuchiya, Masayuki, Hamakubo, Takao

“…We have been investigating the functional display of multipass membrane protein such as transporter or G-protein coupled receptor on the budded baculovirus…”
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