Search Results - "Iwamoto, Tsutomu"
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Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells
Published in Scientific reports (18-12-2017)“…The extracellular environment regulates the dynamic behaviors of cells. However, the effects of hydrostatic pressure (HP) on cell fate determination of…”
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Pannexin 3 functions as an ER Ca2+ channel, hemichannel, and gap junction to promote osteoblast differentiation
Published in The Journal of cell biology (27-06-2011)“…The pannexin proteins represent a new gap junction family. However, the cellular functions of pannexins remain largely unknown. Here, we demonstrate that…”
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Pannexin 3 Inhibits Proliferation of Osteoprogenitor Cells by Regulating Wnt and p21 Signaling
Published in The Journal of biological chemistry (31-01-2014)“…Canonical Wnt signaling and BMP promote the proliferation and differentiation of osteoprogenitors, respectively. However, the regulatory mechanism involved in…”
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Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1
Published in Scientific reports (14-10-2019)“…Signal transmission from the mechanical forces to the various intracellular activities is a fundamental process during tissue development. Despite their…”
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Effect of Nitrogen Gas Post-Curing and Printer Type on the Mechanical Properties of 3D-Printed Hard Occlusal Splint Material
Published in Polymers (22-09-2022)“…Although three-dimensional (3D) printing is clinically convenient to fabricate occlusal splints, it is still unclear how the post-curing method and the printer…”
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Identification of GPI-anchored protein LYPD1 as an essential factor for odontoblast differentiation in tooth development
Published in The Journal of biological chemistry (01-05-2023)“…Lipid rafts are membrane microdomains rich in cholesterol, sphingolipids, glycosylphosphatidylinositol-anchored proteins (GPI-APs), and receptors. These lipid…”
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Deficiency of G protein‐coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein‐related peptidase 4 (Klk4) during pH cycling process
Published in The FASEB journal (01-04-2023)“…Enamel is formed by the repetitive secretion of a tooth‐specific extracellular matrix and its decomposition. Calcification of the enamel matrix via…”
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Effect of 3D printing system and post-curing atmosphere on micro- and nano-wear of additive-manufactured occlusal splint materials
Published in Journal of the mechanical behavior of biomedical materials (01-06-2023)“…Although additive manufacturing has been widely applied for occlusal splint (OS) fabrication, it is still unclear whether 3D printing system and post-curing…”
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Wear behavior of materials for additive manufacturing after simulated occlusion of deciduous dentition
Published in Journal of the mechanical behavior of biomedical materials (01-02-2023)“…To evaluate wear characteristics of materials for additive manufacturing (AM) after a simulated occlusal test in primary teeth. Wear was simulated by means of…”
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Effect of 3D Printer Type and Use of Protection Gas during Post-Curing on Some Physical Properties of Soft Occlusal Splint Material
Published in Polymers (31-10-2022)“…Despite the fact that three-dimensional (3D) printing is frequently used in the manufacturing of occlusal splints, the effects of the 3D printer type and…”
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11
Three-dimensional microscopic comparison of wear behavior between immature and mature enamel: an in vitro study
Published in BMC oral health (25-01-2023)“…Dental enamel, the hardest outermost layer of a human tooth, is subjected to occlusal forces throughout life during different oral function as talking,…”
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Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
Published in Scientific reports (15-02-2023)“…Radiation therapy for head and neck cancers is frequently associated with adverse effects on the surrounding normal tissue. Irreversible damage to…”
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Cell lineage‐ and expression‐based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development
Published in Developmental dynamics (01-08-2021)“…Background Foxc2 is a member of the winged helix/forkhead (Fox) box family of transcription factors. Loss of function of Foxc2 causes craniofacial…”
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bmp-2 Gene-Transferred Skeletal Muscles with Needle-Type Electrodes as Efficient and Reliable Biomaterials for Bone Regeneration
Published in Materials (14-02-2024)“…Bone morphogenetic protein-2 ( ) has a high potential to induce bone tissue formation in skeletal muscles. We developed a bone induction system in skeletal…”
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An ex vivo organ culture screening model revealed that low temperature conditions prevent side effects of anticancer drugs
Published in Scientific reports (23-02-2022)“…Development of chemotherapy has led to a high survival rate of cancer patients; however, the severe side effects of anticancer drugs, including organ…”
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G protein–coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts
Published in The Journal of biological chemistry (06-11-2020)“…Dental enamel, the hardest tissue in the human body, is derived from dental epithelial cell ameloblast-secreted enamel matrices. Enamel mineralization occurs…”
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Pannexin 3 regulates proliferation and differentiation of odontoblasts via its hemichannel activities
Published in PloS one (11-05-2017)“…Highly coordinated regulation of cell proliferation and differentiation contributes to the formation of functionally shaped and sized teeth; however, the…”
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Effect of Surface Polishing on Physical Properties of an Occlusal Splint Material for Additive Manufacturing under Protection Gas Post-Curing Condition
Published in Polymers (25-01-2023)“…The aim of this study was to evaluate the effect of surface polishing as well as the post-curing atmospheres (air and nitrogen gas) on the physical properties…”
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Impact of restorative material on fracture behaviors of class II restoration in endodontically treated deciduous molars
Published in Dental Materials Journal (25-09-2024)“…The purpose of this study was to investigate the fracture behavior of endodontically treated (ET) deciduous molar when directly restored with different…”
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Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation
Published in Frontiers in physiology (24-09-2021)“…Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling…”
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