Search Results - "Iwai, L K"

Large protein as a potential target for use in rabies diagnostics by Santos Katz, I S, Dias, M H, Lima, I F, Chaves, L B, Ribeiro, O G, Scheffer, K C, Iwai, L K

“…Rabies is a zoonotic viral disease that remains a serious threat to public health worldwide. The rabies lyssavirus (RABV) genome encodes five structural…”
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Cellular autoreactivity against heat shock protein 60 in renal transplant patients: peripheral and graft‐infiltrating responses by Caldas, C., Luna, E., Spadafora‐Ferreira, M., Porto, G., Iwai, L. K., Oshiro, S. E., Monteiro, S. M., Fonseca, J. A., Lemos, F., Hammer, J., Ho, P. L., Kalil, J., Coelho, V.

“…Summary Autoreactivity to heat shock protein 60 (Hsp60) has been implicated in the pathogenesis and regulation of chronic inflammation, especially in…”
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T-Cell response to self HSP60 peptides in renal transplant recipients: a regulatory role? by Caldas, C, Spadafora-Ferreira, M, Fonseca, J.A, Luna, E, Iwai, L.K, Kalil, J, Coelho, V

“…T-cell responses to heat shock proteins (Hsp) have been suggested to play a role not only in inflammatory conditions, but also in various human autoimmune…”
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Retro-inverso peptide analogues of Trypanosoma cruzi B13 protein epitopes fail to be recognized by human sera and peripheral blood mononuclear cells by Iwai, L.K, Duranti, M.A, Abel, L.C.J, Juliano, M.A, Kalil, J, Juliano, L, Cunha-Neto, E

“…Retro inverso (RI) analogues of antigenic synthetic peptides, which are made of D-amino acids with a reversed sequence, may mimic the side chain conformation…”
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T-cell molecular mimicry in Chagas disease: identification and partial structural analysis of multiple cross-reactive epitopes between Trypanosoma cruzi B13 and cardiac myosin heavy chain by Iwai, Leo Kei, Juliano, Maria A., Juliano, Luiz, Kalil, Jorge, Cunha-Neto, Edecio

“…Chagas disease cardiomyopathy (CCC) is one of the few examples of post-infectious autoimmunity, where infectious episodes with an established pathogen, the…”
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Proteomic inventory of myocardial proteins from patients with chronic Chagas' cardiomyopathy by Teixeira, P C, Iwai, L K, Kuramoto, A C K, Honorato, R, Fiorelli, A, Stolf, N, Kalil, J, Cunha-Neto, E

“…Chronic Chagas' disease cardiomyopathy (CCC) is an often fatal outcome of Trypanosoma cruzi infection, with a poorer prognosis than other cardiomyopathies. CCC…”
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Trypanosoma cruzi: Conformational Preferences of Antigenic Peptides Bearing the Immunodominant Epitope of the B13 Antigen by Duranti, Márcia A., Franzoni, Lorella, Sartor, Giorgio, Benedetti, Arianna, Iwai, Léo K., Gruber, Arthur, Zingales, Bianca, Guzman, Fanny, Kalil, Jorge, Spisni, Alberto, Cunha-Neto, Edécio

“…Duranti, M. A., Franzoni, L., Sartor, G., Benedetti, A., Iwai, L. K., Gruber, A., Zingales, B., Guzman, F., Kalil, J., Spisni, A., and Cunha-Neto, E. 1999…”
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Systematic Analysis of the Combinatorial Nature of Epitopes Recognized by TCR Leads to Identification of Mimicry Epitopes for Glutamic Acid Decarboxylase 65-Specific TCRs by Uemura, Yasushi, Senju, Satoru, Maenaka, Katsumi, Iwai, Leo Kei, Fujii, Shinji, Tabata, Hiroki, Tsukamoto, Hirotake, Hirata, Shinya, Chen, Yu-Zhen, Nishimura, Yasuharu

“…Accumulating evidence indicates that recognition by TCRs is far more degenerate than formerly presumed. Cross-recognition of microbial Ags by autoreactive T…”
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Establishment of an Expression Cloning System for CD4+ T Cell Epitopes by Fujii, Shinji, Uemura, Yasushi, Iwai, Leo Kei, Ando, Masayuki, Senju, Satoru, Nishimura, Yasuharu

“…We previously reported an epitope presenting vector, pCI, a derivative of a human invariant chain (Ii) expression vector, in which the class II associated…”
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T-Cell Recognition and Cytokine Profile Induced by Melanocyte Epitopes in Patients with HLA-DRB10405-Positive and -Negative Vogt-Koyanagi-Harada Uveitis by Damico, Francisco Max, Cunha-Neto, Edecio, Goldberg, Anna Carla, Iwai, Leo Kei, Marin, Maria Lucia, Hammer, Juergen, Kalil, Jorge, Yamamoto, Joyce Hisae

“…Vogt-Koyanagi-Harada disease (VKH), an autoimmune disease targeted against melanocytes, is associated with HLA-DRB1*0405. This study was undertaken to analyze…”
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Proteomic inventory of myocardial proteins from patients with chronic Chagas' cardiomyopathy by Teixeira, P C, Iwai, L K, Kuramoto, ACK, Honorato, R, Fiorelli, A, Stolf, N, Kalil, J, Cunha-Neto, E

“…Chronic Chagas' disease cardiomyopathy (CCC) is an often fatal outcome of Trypanosoma cruzi infection, with a poorer prognosis than other cardiomyopathies. CCC…”
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PROLIFERATIVE RESPONSE OF LYMPHOCYTES WITH 41 PEPTIDES OF GP 43 IN PATIENTS WITH PARACOCCIDIOIDOMYCOSIS by Sadahiro, A, Roque, A C M, Iwai, L K, Cunha-Neto, E, Shikanai-Yasuda, M A

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Establishment of an Expression Cloning System for CD4 super(+) T Cell Epitopes by Fujii, S, Uemura, Y, Iwai, L K, Ando, M, Senju, S, Nishimura, Y

“…We previously reported an epitope presenting vector, pCI, a derivative of a human invariant chain (Ii) expression vector, in which the class II associated…”
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Identification of multiple HLA-A0201-restricted cruzipain and FL-160 CD8 + epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients by Fonseca, Simone G., Moins-Teisserenc, Hélène, Clave, Emmanuel, Ianni, Bárbara, Nunes, Vera Lopes, Mady, Charles, Iwai, Leo K., Sette, Alessandro, Sidney, John, Marin, Maria Lúcia C., Goldberg, Anna Carla, Guilherme, Luiza, Charron, Dominique, Toubert, Antoine, Kalil, Jorge, Cunha-Neto, Edecio

“…Chronic Chagas disease occurs in 16 million individuals chronically infected by the protozoan Trypanosoma cruzi in Latin America, and may lead to a dilated…”
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In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitized individuals by Iwai, Leo Kei, Yoshida, Márcia, Sidney, John, Shikanai-Yasuda, Maria Aparecida, Goldberg, Anna Carla, Juliano, Maria Aparecida, Hammer, Jurgen, Juliano, Luiz, Sette, Alessandro, Kalil, Jorge, Travassos, Luiz Rodolpho, Cunha-Neto, Edecio

“…One of the major drawbacks limiting the use of synthetic peptide vaccines in genetically distinct populations is the fact that different epitopes are…”
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Radical production from free and peptide-bound methionine sulfoxide oxidation by peroxynitrite and hydrogen peroxide/iron(II) by Nakao, Lia S, Iwai, Leo K, Kalil, Jorge, Augusto, Ohara

“…Methionine sulfoxide is a post-translational protein modification that has been receiving increasing attention in the literature. Here we used electron…”
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T cell epitope characterization in tandemly repetitive Trypanosoma cruzi B13 protein by Abel, Lúcia C.J., Iwai, Leo K., Viviani, Wladia, Bilate, Angelina M., Faé, Kellen C., Ferreira, Renata C., Goldberg, Anna C., Juliano, Luiz, Juliano, Maria A., Ianni, Bárbara, Mady, Charles, Gruber, Arthur, Hammer, Juergen, Sinigaglia, Francesco, Kalil, Jorge, Cunha-Neto, Edecio

“…Proteins containing tandemly repetitive sequences are present in several immunodominant protein antigens in pathogenic protozoan parasites. The tandemly…”
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Latex allergy and cross-reactivity to manioc: Report of 2 cases by Galvao, C.E.S., Iwai, L.K., Andrade, M.E.B., Kalil, J., Castro, F.F.Morato

“…Allergy to natural latex is frequently associated with hypersensitivity to fruits and recently, a case of cross-reactivity to manioc was reported. The authors…”
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