Search Results - "Iwahashi, H"

Predominance of β-Cell Neogenesis Rather Than Replication in Humans With an Impaired Glucose Tolerance and Newly Diagnosed Diabetes by Yoneda, S, Uno, S, Iwahashi, H, Fujita, Y, Yoshikawa, A, Kozawa, J, Okita, K, Takiuchi, D, Eguchi, H, Nagano, H, Imagawa, A, Shimomura, I

“…Context: A decrease in pancreatic β-cell mass is involved in the development of type 2 diabetes. Objective: The purpose of this study was to evaluate the…”
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Real-Time PCR: Revolutionizing Detection and Expression Analysis of Genes by Deepak, Sa, Kottapalli, Kr, Rakwal, R, Oros, G, Rangappa, Ks, Iwahashi, H, Masuo, Y, Agrawal, Gk

“…Invention of polymerase chain reaction (PCR) technology by Kary Mullis in 1984 gave birth to real-time PCR. Real-time PCR - detection and expression analysis…”
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Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial by Katakami, Naoto, Mita, Tomoya, Yoshii, Hidenori, Shiraiwa, Toshihiko, Yasuda, Tetsuyuki, Okada, Yosuke, Kurozumi, Akira, Hatazaki, Masahiro, Kaneto, Hideaki, Osonoi, Takeshi, Yamamoto, Tsunehiko, Kuribayashi, Nobuichi, Maeda, Kazuhisa, Yokoyama, Hiroki, Kosugi, Keisuke, Ohtoshi, Kentaro, Hayashi, Isao, Sumitani, Satoru, Tsugawa, Mamiko, Ryomoto, Kayoko, Kato, Ken, Nakamura, Tadashi, Kawashima, Satoshi, Sato, Yasunori, Watada, Hirotaka, Shimomura, Iichiro

“…This study aimed to assess the long-term effects of tofogliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on atherosclerosis progression and major…”
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Draft Genome Sequence of Lactiplantibacillus pentosus AWA1501, Isolated from Awa-bancha by Ito, F, Niwa, R, Syaputri, Y, Ikagawa, Y, Mizuno, T, Horie, M, Iwahashi, H

“…Lactiplantibacillus pentosus AWA1501 was isolated from the traditional Japanese tea Awa-bancha. Previous studies have reported that this species becomes…”
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Detection and identification of 1-methylethyl and methyl radicals generated by irradiating tea tree (Melaleuca alternifolia) oil with visible light (436 nm) in the presence of flavin mononucleotide and ferrous ion by Mori, H-M, Iwahashi, H

“…Here, we determined the electron spin resonance (ESR) spectra of standard reaction mixtures (I) containing 25 μM flavin mononucleotide (FMN), 0.018% tea tree…”
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Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-α in patients with recent-onset type 1 diabetes by Uno, S, Imagawa, A, Okita, K, Sayama, K, Moriwaki, M, Iwahashi, H, Yamagata, K, Tamura, S, Matsuzawa, Y, Hanafusa, T, Miyagawa, J, Shimomura, I

“…Aims/hypothesis Type 1A diabetes results from autoimmune destruction of pancreatic beta cells. We examined the involvement of TNF-α and IL-1β, as well as of T…”
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Bioassay of cadmium using a DNA microarray: Genome-wide expression patterns of Saccharomyces cerevisiae response to cadmium by Momose, Yuko, Iwahashi, Hitoshi

“…DNA microarray technology enables genome‐wide detection of cell response at the transcriptional level. We are planning to make bioassay systems that can detect…”
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Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays onset of autoimmune type 1 diabetes by Zhang, J, Tokui, Y, Yamagata, K, Kozawa, J, Sayama, K, Iwahashi, H, Okita, K, Miuchi, M, Konya, H, Hamaguchi, T, Namba, M, Shimomura, I, Miyagawa, J-i

“…Aims/hypothesis We examined the effect of glucagon-like peptide-1 (GLP-1) on the development of diabetes and islet morphology in NOD mice by administering…”
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The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus by Katakami, Naoto, Mita, Tomoya, Yoshii, Hidenori, Shiraiwa, Toshihiko, Yasuda, Tetsuyuki, Okada, Yosuke, Torimoto, Keiichi, Umayahara, Yutaka, Kaneto, Hideaki, Osonoi, Takeshi, Yamamoto, Tsunehiko, Kuribayashi, Nobuichi, Maeda, Kazuhisa, Yokoyama, Hiroki, Kosugi, Keisuke, Ohtoshi, Kentaro, Hayashi, Isao, Sumitani, Satoru, Tsugawa, Mamiko, Ryomoto, Kayoko, Taki, Hideki, Nakamura, Tadashi, Kawashima, Satoshi, Sato, Yasunori, Watada, Hirotaka, Shimomura, Iichiro

“…Introduction Treatment-related quality of life (QOL) is an important aspect of diabetes management. We evaluated the influence of a sodium-glucose…”
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In vitro evaluation of cellular responses induced by stable fullerene C₆₀ medium dispersion by Horie, Masanori, Nishio, Keiko, Kato, Haruhisa, Shinohara, Naohide, Nakamura, Ayako, Fujita, Katsuhide, Kinugasa, Shinichi, Endoh, Shigehisa, Yamamoto, Kazuhiro, Yamamoto, Osamu, Niki, Etsuo, Yoshida, Yasukazu, Iwahashi, Hitoshi

“…Because of the expansion of the functionalities available for modification of fullerene C₆₀ and its derivatives, their uses are increasing. However, the…”
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Clinical and Immunogenetic Characteristics of Fulminant Type 1 Diabetes Associated with Pregnancy by Shimizu, I., Makino, H., Imagawa, A., Iwahashi, H., Uchigata, Y., Kanatsuka, A., Kawasaki, E., Kobayashi, T., Shimada, A., Maruyama, T., Hanafusa, T.

“…Objective: The objective of this study was to characterize the clinical and immunogenetic features of Japanese pregnancy-associated fulminant type 1 diabetes…”
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Fulminant type 1 diabetes as a high risk group for diabetic microangiopathy--a nationwide 5-year-study in Japan by Murase, Y, Imagawa, A, Hanafusa, T, Iwahashi, H, Uchigata, Y, Kanatsuka, A, Kawasaki, E, Kobayashi, T, Shimada, A, Shimizu, I, Maruyama, T, Makino, H

“…Aims/hypothesis The aim of the present study was to assess the development of microangiopathy in patients with fulminant type 1 diabetes, a novel subtype of…”
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Comprehensive gene expression analysis of the response to straight-chain alcohols in Saccharomyces cerevisiae using cDNA microarray by Fujita, K, Matsuyama, A, Kobayashi, Y, Iwahashi, H

“…Aims:  The purpose of this study was to examine the gene expression profiles of yeast Saccharomyces cerevisiae subjected to straight‐chain alcohols. Methods…”
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Cellular responses induced by cerium oxide nanoparticles: induction of intracellular calcium level and oxidative stress on culture cells by Horie, Masanori, Nishio, Keiko, Kato, Haruhisa, Fujita, Katsuhide, Endoh, Shigehisa, Nakamura, Ayako, Miyauchi, Arisa, Kinugasa, Shinichi, Yamamoto, Kazuhiro, Niki, Etsuo, Yoshida, Yasukazu, Hagihara, Yoshihisa, Iwahashi, Hitoshi

“…Cerium oxide (CeO2) is an important metal oxide used for industrial products. Many investigations about the cellular influence of CeO2 nanoparticles have been…”
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Pancreatic beta and alpha cells are both decreased in patients with fulminant type 1 diabetes : a morphometrical assessment by SAYAMA, K, IMAGAWA, A, HANAFUSA, T, MIYAGAWA, J, SHIMOMURA, I, OKITA, K, UNO, S, MORIWAKI, M, KOZAWA, J, IWAHASHI, H, YAMAGATA, K, TAMURA, S, MATSUZAWA, Y

“…We have previously reported that fulminant type 1 diabetes is characterised by an absence of diabetes-related antibodies and a remarkably abrupt onset…”
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Effects of coffee consumption on oxidative susceptibility of low-density lipoproteins and serum lipid levels in humans by Yukawa, G S, Mune, M, Otani, H, Tone, Y, Liang, X-M, Iwahashi, H, Sakamoto, W

“…Since little is known about how coffee intake affects low-density lipoprotein (LDL) oxidative susceptibility and serum lipid levels, we conducted an in vivo…”
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Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus by MORIWAKI, M, ITOH, N, HANAFUSA, T, MATSUZAWA, Y, MIYAGAWA, J, YAMAMOTO, K, IMAGAWA, A, YAMAGATA, K, IWAHASHI, H, NAKAJIMA, H, NAMBA, M, NAGATA, S

“…Type I (insulin-dependent) diabetes results mainly from T-cell-mediated autoimmune destruction of pancreatic beta cells. Cytotoxic T lymphocytes destroy target…”
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Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy by Tsujimoto, Yoshihide, Iwahashi, Hiromi, Eguchi, Yutaka, Yasuhara, Noriko, Hanafusa, Toshiaki, Matsuzawa, Yuji

“…Spinal muscular atrophy (SMA) is a motor neuron disease characterized by degeneration of the anterior horn cells of the spinal cord. It is a common fatal…”
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The quasi 2-day wave observed in the polar mesosphere: Comparison of the characteristics observed at Tromsø and Poker Flat by Nozawa, S., Iwahashi, H., Brekke, A., Hall, C. M., Meek, C., Manson, A., Oyama, S., Murayama, Y., Fujii, R.

“…A comparison of the quasi 2‐day wave (Q2DW) observed at Tromsø (69.6°N, 19.2°E) and Poker Flat (65.2°, 147.6°W) is presented at four heights of 70, 76, 82, and…”
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Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line : inhibition by Bcl-2 by IWAHASHI, H, HANAFUSA, T, TSUJIMOTO, Y, MATSUZAWA, Y, EGUCHI, T, NAKAJIMA, H, MIYAGAWA, J, ITOH, N, TOMITA, K, NAMBA, M, KUWAJIMA, M, NOGUCHI, T

“…Cytokines are thought to contribute to the induction of pancreatic beta-cell destruction in insulin-dependent diabetes mellitus. The molecular mechanisms that…”
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