Search Results - "Iwahara, J"

The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA by Iwahara, Junji, Iwahara, Mizuho, Daughdrill, Gary W., Ford, Joseph, Clubb, Robert T.

“…The AT‐rich interaction domain (ARID) is a DNA‐binding module found in many eukaryotic transcription factors. Using NMR spectroscopy, we have determined the…”
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Solution structure of the DNA binding domain from dead ringer, a sequence-specific AT-rich interaction domain (ARID) by Iwahara, J, Clubb, R.T

“…The Dead ringer protein from Drosophila melanogaster is a transcriptional regulatory protein required for early embryonic development. It is the founding…”
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Improved NMR spectra of a protein-DNA complex through rational mutagenesis and the application of a sensitivity optimized isotope-filtered NOESY experiment by Iwahara, J, Wojciak, J M, Clubb, R T

“…The NMR spectra of the complex between the DNA-binding domain of the Dead ringer protein (DRI-DBD, Gly262-Gly398) and its DNA binding site (DRI-DBD:DNA, 26…”
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The Mu repressor-DNA complex contains an immobilized 'wing' within the minor groove by Clubb, Robert T, Wojciak, Jonathan M, Iwahara, Junji

“…We have determined the solution structure of the complex between the 'winged-helix' enhancer binding domain of the Mu repressor protein and its cognate DNA…”
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A helix-turn-helix structure unit in human centromere protein B (CENP-B) by Iwahara, Junji, Kigawa, Takanori, Kitagawa, Katsumi, Masumoto, Hiroshi, Okazaki, Tuneko, Yokoyama, Shigeyuki

“…CENP‐B has been suggested to organize arrays of centromere satellite DNA into a higher order structure which then directs centromere formation and kinetochore…”
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Detecting transient intermediates in macromolecular binding by paramagnetic NMR by Clore, G. Marius, Iwahara, Junji

“…Macromolecular complex formation is governed by two opposing constraints of specificity and speed. Kinetic and theoretical considerations suggest that…”
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Direct Observation of Enhanced Translocation of a Homeodomain between DNA Cognate Sites by NMR Exchange Spectroscopy by Iwahara, Junji, Clore, G. Marius

“…A novel approach is presented for studying the kinetics of specific protein−DNA interactions by NMR exchange spectroscopy. The experimental design involves the…”
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Regulation of transcription factors via natural decoys in genomic DNA by Kemme, Catherine A., Nguyen, Dan, Chattopadhyay, Abhijnan, Iwahara, Junji

“…Eukaryotic genomic DNA contains numerous high-affinity sites for transcription factors. Only a small fraction of these sites directly regulates target genes…”
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Structure of Sortase, The Transpeptidase That Anchors Proteins to the Cell Wall of Staphylococcus aureus by Ilangovan, Udayar, Ton-That, Hung, Iwahara, Junji, Schneewind, Olaf, Clubb, Robert T.

“…Surface proteins of Gram-positive bacteria play important roles during the pathogenesis of human infections and require sortase for anchoring to the cell-wall…”
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Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA by Tanaka, Yoshinori, Nureki, Osamu, Kurumizaka, Hitoshi, Fukai, Shuya, Kawaguchi, Shinichi, Ikuta, Mari, Iwahara, Junji, Okazaki, Tsuneko, Yokoyama, Shigeyuki

“…The human centromere protein B (CENP‐B), one of the centromere components, specifically binds a 17 bp sequence (the CENP‐B box), which appears in every other…”
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EDTA-Derivatized Deoxythymidine as a Tool for Rapid Determination of Protein Binding Polarity to DNA by Intermolecular Paramagnetic Relaxation Enhancement by Iwahara, Junji, Anderson, D. Eric, Murphy, Elizabeth C, Clore, G. Marius

“…EDTA-derivatized deoxythymidine (dT-EDTA), incorporated into DNA and complexed to Fe2+ in the presence of dithiothreitol, is a widely used reagent for…”
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Characterization of Nonspecific Protein-DNA Interactions by super(1)H Paramagnetic Relaxation Enhancement by Iwahara, J, Schwieters, C D, Clore, G M

“…Nonspecific protein-DNA interactions play an important role in a variety of contexts related to DNA packaging, nucleoprotein complex formation, and gene…”
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Regional Polysterism in the GTP-Bound Form of the Human c-Ha-Ras Protein by Ito, Yutaka, Yamasaki, Kazuhiko, Iwahara, Junji, Terada, Tohru, Kamiya, Akihide, Shirouzu, Mikako, Muto, Yutaka, Kawai, Gota, Yokoyama, Shigeyuki, Laue, Ernest D, Wälchli, Markus, Shibata, Takehiko, Nishimura, Susumu, Miyazawa, Tatsuo

“…The backbone 1H, 13C, and 15N resonances of the c-Ha-Ras protein [a truncated version consisting of residues 1−171, Ras(1−171)] bound with GMPPNP (a slowly…”
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Regulation of Directionality in Bacteriophage λ Site-specific Recombination: Structure of the Xis Protein by Sam, My D., Papagiannis, Christie V., Connolly, Kevin M., Corselli, Leah, Iwahara, Junji, Lee, James, Phillips, Martin, Wojciak, Jonathan M., Johnson, Reid C., Clubb, Robert T.

“…Upon induction of a bacteriophage λ lysogen, a site-specific recombination reaction excises the phage genome from the chromosome of its bacterial host. A…”
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Compensating increases in protein backbone flexibility occur when the Dead ringer AT‐rich interaction domain (ARID) binds DNA: A nitrogen‐15 relaxation study by Iwahara, Junji, Peterson, Robert D., Clubb, Robert T.

“…AT‐rich interaction domains (ARIDs) are found in a large number of eukaryotic transcription factors that regulate cell proliferation, differentiation, and…”
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Studies of specific IgE, IgG and IgG4 antibodies to egg white, milk and soybean in children with atopic dermatitis by Iikura, Y, Nagakura, T, Akimoto, K, Iwahara, J, Uekusa, T, Onda, T

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Solution structure of the Eps15 homology domain of a human POB1 (partner of RalBP1) by Koshiba, Seizo, Kigawa, Takanori, Iwahara, Junji, Kikuchi, Akira, Yokoyama, Shigeyuki

“…The solution structure of the Eps15 homology (EH) domain of a human POB1 (partner of RalBP1) has been determined by uniform 13C/ 15N labeling and heteronuclear…”
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Solution structure determination of the two DNA-binding domains in the Shizosaccharomyces pombe Abp1 protein by a combination of dipolar coupling and diffusion anisotropy restraints by Kikuchi, Jun, Iwahara, Junji, Kigawa, Takanori, Murakami, Yota, Okazaki, Tsuneko, Yokoyama, Shigeyuki

“…We have solved the solution structure of the N-terminal region of the fission yeast centromere protein, Abp1, bound to a 21-base pair DNA fragment bearing its…”
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Letter to the Editor: 1H, 13C and 15N resonance assignments of the AT-rich interaction domain from the Dead Ringer protein by Iwahara, J, Clubb, R T

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Assignment of the 1H, 13C and 15N signals of Sortase by Ilangovan, U, Iwahara, J, Ton-That, H, Schneewind, O, Clubb, R T

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