Search Results - "Ivey, Melanie E"

Endothelin-1 signalling in vascular smooth muscle: Pathways controlling cellular functions associated with atherosclerosis by Ivey, Melanie E, Osman, Narin, Little, Peter J

“…Abstract Atherosclerosis is the primary ischaemic vascular condition underlying a majority of cardiovascular disease related deaths. Endothelin-1 is a…”
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Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways by Ivey, Melanie E, Little, Peter J

“…Abstract Introduction Atherosclerosis is the underlying pathological process of most cardiovascular disease. Thrombin is a serine protease which can activate…”
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Actions of calcium channel blockers on vascular proteoglycan synthesis: relationship to atherosclerosis by Survase, Soniya, Ivey, Melanie E, Nigro, Julie, Osman, Narin, Little, Peter J

“…Calcium channel blockers (CCBs) are a widely used group of antihypertensive agents. CCBs are efficacious in the reduction of blood pressure but the extent to…”
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Endothelin-1 activates ETA receptors on human vascular smooth muscle cells to yield proteoglycans with increased binding to LDL by Ballinger, Mandy L, Ivey, Melanie E, Osman, Narin, Thomas, Walter G, Little, Peter J

“…Abstract Objective Lipid retention in the vessel wall by glycosaminoglycan (GAG) chains on chondroitin/dermatan sulfate proteoglycans synthesized by vascular…”
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Endothelin-1 actions on vascular smooth muscle cell functions as a target for the prevention of atherosclerosis by Little, Peter J, Ivey, Melanie E, Osman, Narin

“…The formation and progression of atherosclerotic plaques followed by rupture, thrombus formation and vessel blockage leads to ischemic tissue damage and the…”
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Inhibitory activity of clinical thiazolidinedione peroxisome proliferator activating receptor-γ ligands toward internal mammary artery, radial artery, and saphenous vein smooth muscle cell proliferation by DE DIOS, Stephanie T, BRUEMMER, Dennis, DILLEY, Rodney J, IVEY, Melanie E, JENNINGS, Garry L. R, LAW, Ronald E, LITTLE, Peter J

“…The proliferation of vascular smooth muscle cells (VSMCs) is a known response to arterial injury that is an important part of the process of restenosis and…”
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Regulation of the atherogenic properties of vascular smooth muscle proteoglycans by oral anti-hyperglycemic agents by de Dios, Stephanie T, Frontanilla, Karen V, Nigro, Julie, Ballinger, Mandy L, Ivey, Melanie E, Cawson, Elizabeth A, Little, Peter J

“…Abstract The present study aimed to investigate the actions of several classes of oral hypoglycemic agents [e.g., sulfonylureas (SUs), biguanides (BGs) and…”
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Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells by Ballinger, Mandy L., Thomas, Merlin C., Nigro, Julie, Ivey, Melanie E., Dilley, Rodney J., Little, Peter J.

“…Glycated and carboxy-methylated proteins do not directly activate human vascular smooth muscle cells. Advanced glycation end products (AGEs) accumulate in…”
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The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells by Nigro, Julie, Potter-Perigo, Susan, Ivey, Melanie E., de Dios, Stephanie T., Evanko, Stephen P., Wight, Thomas N., Little, Peter J.

“…Abstract PPAR ligands are important effectors of energy metabolism and can modify proteoglycan synthesis by vascular smooth muscle cells (VSMCs). Describing…”
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The pro-atherosclerotic actions of thrombin on extracellular matrix by Ivey, Melanie E., Potter-Perigo, Susan, Wight, Thomas N., Little, Peter J.

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