Search Results - "Ivatt, Rachael M"

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy by Ivatt, Rachael M., Sanchez-Martinez, Alvaro, Godena, Vinay K., Brown, Stephen, Ziviani, Elena, Whitworth, Alexander J.

“…Genetic analysis of Parkinson disease (PD) has identified several genes whose mutation causes inherited parkinsonism, as well as risk loci for sporadic PD…”
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The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy by Pogson, Joe H, Ivatt, Rachael M, Sanchez-Martinez, Alvaro, Tufi, Roberta, Wilson, Emma, Mortiboys, Heather, Whitworth, Alexander J

“…Mutations in PINK1, a mitochondrially targeted serine/threonine kinase, cause autosomal recessive Parkinson's disease (PD). Substantial evidence indicates that…”
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Molecular Mechanisms of PINK1-Related Neurodegeneration by Pogson, Joe H., Ivatt, Rachael M., Whitworth, Alexander J.

“…PINK1 is a mitochondrially targeted kinase that has been linked to a rare monogenic form of Parkinson’s disease (PD), a common neurodegenerative disease…”
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SREBF1 links lipogenesis to mitophagy and sporadic Parkinson disease by Ivatt, Rachael M, Whitworth, Alexander J

“…Mitochondrial quality control has an impact on many diseases, but intense research has focused on the action of 2 genes linked to heritable forms of Parkinson…”
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The many faces of mitophagy by Ivatt, Rachael M, Whitworth, Alexander J

“…Failure to maintain mitochondrial integrity is linked to age‐related conditions, such as neurodegeneration. Two genes linked to Parkinson's disease, PINK1 and…”
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The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy by Burchell, Victoria S, Nelson, David E, Sanchez-Martinez, Alvaro, Delgado-Camprubi, Marta, Ivatt, Rachael M, Pogson, Joe H, Randle, Suzanne J, Wray, Selina, Lewis, Patrick A, Houlden, Henry, Abramov, Andrey Y, Hardy, John, Wood, Nicholas W, Whitworth, Alexander J, Laman, Heike, Plun-Favreau, Helene

“…Mutations in the gene encoding the F-box domain–containing protein Fbxo7 are genetically associated to an autosomal recessive form of early-onset Parkinson's…”
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The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy: e1004815 by Pogson, Joe H, Ivatt, Rachael M, Sanchez-Martinez, Alvaro, Tufi, Roberta, Wilson, Emma, Mortiboys, Heather, Whitworth, Alexander J

“…Mutations in PINK1, a mitochondrially targeted serine/threonine kinase, cause autosomal recessive Parkinson's disease (PD). Substantial evidence indicates that…”
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The Parkinson’s disease genes Fbxo7 and Parkin interact to mediate mitophagy by Burchell, Victoria S, Nelson, David E, Sanchez-Martinez, Alvaro, Delgado-Camprubi, Marta, Ivatt, Rachael M, Pogson, Joe H, Randle, Suzanne J, Wray, Selina, Lewis, Patrick A, Houlden, Henry, Abramov, Andrey Y, Hardy, John, Wood, Nicholas W, Whitworth, Alexander J, Laman, Heike, Plun-Favreau, Helene

“…Compelling evidence indicates that two autosomal recessive Parkinson’s disease genes, PINK1 ( PARK6 ) and Parkin ( PARK2 ), co-operate to mediate the…”
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