Search Results - "Ivars, David"
-
1
Fluorescence in situ hybridization analysis does not increase detection rate for trisomy 8 in chronic myelomonocytic leukemia
Published in Leukemia & lymphoma (01-01-2015)Get full text
Journal Article -
2
Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload
Published in Clinical biochemistry (01-11-2017)“…To assess the generation of reactive oxygen species (ROS) and the involvement of the main antioxidant pathways in low/intermediate-1-risk myelodysplastic…”
Get full text
Journal Article -
3
Early ROS-mediated DNA damage and oxidative stress biomarkers in Monoclonal B Lymphocytosis
Published in Cancer letters (28-04-2012)“…Abstract Monoclonal B Lymphocytosis (MBL) is defined as asymptomatic monoclonal B-cell expansion characterised by a CLL-phenotype, but with less than 5 × 109…”
Get full text
Journal Article -
4
Chronic lymphocytic leukemia with isochromosome 17q: An aggressive subgroup associated with TP53 mutations and complex karyotypes
Published in Cancer letters (28-11-2017)“…Although i(17q) [i(17q)] is frequently detected in hematological malignancies, few studies have assessed its clinical role in chronic lymphocytic leukemia…”
Get full text
Journal Article -
5
A two-step approach for sequencing spliceosome-related genes as a complementary diagnostic assay in MDS patients with ringed sideroblasts
Published in Leukemia research (01-05-2017)“…Highlights • Mutations in spliceosome-related genes in 94.3% of MDS-RS. • Presence of double mutations in the splicing machinery genes. • Good prognosis of…”
Get full text
Journal Article -
6
Impact of azacitidine on red blood cell alloimmunisation in myelodysplastic syndrome
Published in Blood transfusion = Trasfusione del sangue (01-09-2017)“…The incidence of alloimmunisation in myelodysplastic syndromes (MDS) during the era of supportive treatment ranges from 9 to 56%. However, it is unknown if the…”
Get full text
Journal Article -
7
Increased Oxidative Damage Associated with Unfavorable Cytogenetic Subgroups in Chronic Lymphocytic Leukemia
Published in BioMed research international (01-01-2014)“…Oxidative stress contributes to genomic instability in chronic lymphocytic leukemia (CLL), but its relationship with the acquisition of specific chromosomal…”
Get full text
Journal Article -
8
Chromosome 8 Abnormalities (8p Losses and 8q Gains) in Patients with Chronic Lymphocytic Leukemia (CLL) and Del(17p)
Published in Blood (06-12-2014)“…Basis. Abnormalities in chromosome 8 (8p-/8q+) are observed in 2-5% of CLL patients. Microarray studies have revealed up to 30-40% of 8 alterations in del(17p)…”
Get full text
Journal Article -
9
Clinical and Biological Characterization of Patients with Low/Intermediate-1 Risk Myelodysplastic Syndrome and Iron Overload
Published in Blood (16-11-2012)“…Abstract 4956 Patients with Myelodysplastic Syndrome (MDS) are susceptible to developing iron overload as a response to the red blood cell (RBC) transfusions…”
Get full text
Journal Article -
10
Application of FISH 7q in MDS patients without monosomy 7 or 7q deletion by conventional G-banding cytogenetics: Does −7/7q− detection by FISH have prognostic value?
Published in Leukemia research (01-04-2013)“…Abstract Chromosomal abnormalities are detected in 40–60% of patients with de novo myelodysplastic syndromes (MDS). This study used the FISH technique in 773…”
Get full text
Journal Article