Search Results - "Ivanova, Elena V"

DNA breaks and chromosome pulverization from errors in mitosis by Crasta, Karen, Ganem, Neil J., Dagher, Regina, Lantermann, Alexandra B., Ivanova, Elena V., Pan, Yunfeng, Nezi, Luigi, Protopopov, Alexei, Chowdhury, Dipanjan, Pellman, David

“…The involvement of whole-chromosome aneuploidy in tumorigenesis is the subject of debate, in large part because of the lack of insight into underlying…”
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EGFR Inhibition Enhances the Cellular Uptake and Antitumor-Activity of the HER3 Antibody-Drug Conjugate HER3-DXd by Haikala, Heidi M, Lopez, Timothy, Köhler, Jens, Eser, Pinar O, Xu, Man, Zeng, Qing, Teceno, Tyler J, Ngo, Kenneth, Zhao, Yutong, Ivanova, Elena V, Bertram, Arrien A, Leeper, Brittaney A, Chambers, Emily S, Adeni, Anika E, Taus, Luke J, Kuraguchi, Mari, Kirschmeier, Paul T, Yu, Channing, Shiose, Yoshinobu, Kamai, Yasuki, Qiu, Yang, Paweletz, Cloud P, Gokhale, Prafulla C, Jänne, Pasi A

“…Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) are the standard-of-care treatment for -mutant non-small cell lung cancers (NSCLC)…”
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Amplification of Wild-type KRAS Imparts Resistance to Crizotinib in MET Exon 14 Mutant Non-Small Cell Lung Cancer by Bahcall, Magda, Awad, Mark M, Sholl, Lynette M, Wilson, Frederick H, Xu, Man, Wang, Stephen, Palakurthi, Sangeetha, Choi, Jihyun, Ivanova, Elena V, Leonardi, Giulia C, Ulrich, Bryan C, Paweletz, Cloud P, Kirschmeier, Paul T, Watanabe, Masayuki, Baba, Hideo, Nishino, Mizuki, Nagy, Rebecca J, Lanman, Richard B, Capelletti, Marzia, Chambers, Emily S, Redig, Amanda J, VanderLaan, Paul A, Costa, Daniel B, Imamura, Yu, Jänne, Pasi A

“…MET inhibitors can be effective therapies in patients with exon 14 ( ex14) mutant non-small cell lung cancer (NSCLC). However, long-term efficacy is limited by…”
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Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer by Nardi, Francesca, Perurena, Naiara, Schade, Amy E, Li, Ze-Hua, Ngo, Kenneth, Ivanova, Elena V, Saldanha, Aisha, Li, Chendi, Gokhale, Prafulla C, Hata, Aaron N, Barbie, David A, Paweletz, Cloud P, Jänne, Pasi A, Cichowski, Karen

“…Despite the success of KRAS G12C inhibitors in non-small cell lung cancer (NSCLC), more effective treatments are needed. One preclinical strategy has been to…”
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Unveiling the contourite depositional system in the Vema Fracture Zone (Central Atlantic) by Borisov, Dmitrii G., Frey, Dmitry I., Ivanova, Elena V., Dmitrevskiy, Nikolay N., Levchenko, Oleg V., Fomin, Vladimir V., Ligi, Marco

“…A combination of a high sediment input and intense bottom currents often leads to the formation of contourites (sediments deposited or significantly reworked…”
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Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors by Ercan, Dalia, Xu, Chunxiao, Yanagita, Masahiko, Monast, Calixte S, Pratilas, Christine A, Montero, Joan, Butaney, Mohit, Shimamura, Takeshi, Sholl, Lynette, Ivanova, Elena V, Tadi, Madhavi, Rogers, Andrew, Repellin, Claire, Capelletti, Marzia, Maertens, Ophélia, Goetz, Eva M, Letai, Anthony, Garraway, Levi A, Lazzara, Matthew J, Rosen, Neal, Gray, Nathanael S, Wong, Kwok-Kin, Jänne, Pasi A

“…The clinical efficacy of epidermal growth factor receptor (EGFR) kinase inhibitors is limited by the development of drug resistance. The irreversible EGFR…”
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Phase II and Biomarker Study of Cabozantinib in Metastatic Triple‐Negative Breast Cancer Patients by Tolaney, Sara M., Ziehr, David R., Guo, Hao, Ng, Mei R., Barry, William T., Higgins, Michaela J., Isakoff, Steven J., Brock, Jane E., Ivanova, Elena V., Paweletz, Cloud P., Demeo, Michelle K., Ramaiya, Nikhil H., Overmoyer, Beth A., Jain, Rakesh K., Winer, Eric P., Duda, Dan G.

“…Currently, no targeted therapies are available for metastatic triplenegative breast cancer (mTNBC). We evaluated the safety, efficacy, and biomarkers of…”
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PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas by Zheng, Hongwu, Ying, Haoqiang, Wiedemeyer, Ruprecht, Yan, Haiyan, Quayle, Steven N., Ivanova, Elena V., Paik, Ji-Hye, Zhang, Hailei, Xiao, Yonghong, Perry, Samuel R., Hu, Jian, Vinjamoori, Anant, Gan, Boyi, Sahin, Ergun, Chheda, Milan G., Brennan, Cameron, Wang, Y. Alan, Hahn, William C., Chin, Lynda, DePinho, Ronald A.

“…A hallmark feature of glioblastoma is its strong self-renewal potential and immature differentiation state, which contributes to its plasticity and therapeutic…”
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The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma Pathogenesis by Carrasco, Daniel R., Sukhdeo, Kumar, Protopopova, Marina, Sinha, Raktim, Enos, Miriam, Carrasco, Daniel E., Zheng, Mei, Mani, Mala, Henderson, Joel, Pinkus, Geraldine S., Munshi, Nikhil, Horner, James, Ivanova, Elena V., Protopopov, Alexei, Anderson, Kenneth C., Tonon, Giovanni, DePinho, Ronald A.

“…Multiple myeloma (MM) evolves from a highly prevalent premalignant condition termed MGUS. The factors underlying the malignant transformation of MGUS are…”
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Semen microbiota and cytokines of healthy and infertile men by Bukharin, Oleg, Perunova, Natalya, Ivanova, Elena, Chaynikova, Irina, Bekpergenova, Anastasia, Bondarenko, Taisiya, Kuzmin, Michael

“…In this study, we determined the levels of cytokine secretory inhibitors and the microbiota biofilms of semen from healthy and infertile subjects. A total of…”
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Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects by Wang, Yufei, Buck, Alicia, Piel, Brandon, Zerefa, Luann, Murugan, Nithyassree, Coherd, Christian D, Miklosi, Andras G, Johal, Haraman, Bastos, Ricardo Nunes, Huang, Kun, Ficial, Miriam, Laimon, Yasmin Nabil, Signoretti, Sabina, Zhong, Zhou, Hoang, Song-My, Kastrunes, Gabriella M, Grimaud, Marion, Fayed, Atef, Yuan, Hsien-Chi, Nguyen, Quang-De, Thai, Tran, Ivanova, Elena V, Paweletz, Cloud P, Wu, Ming-Ru, Choueiri, Toni K, Wee, Jon O, Freeman, Gordon J, Barbie, David A, Marasco, Wayne A

“…One of the major hurdles that has hindered the success of chimeric antigen receptor (CAR) T cell therapies against solid tumors is on-target off-tumor (OTOT)…”
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Electrophysical Characteristics of Acrylonitrile Butadiene Styrene Composites Filled with Magnetite and Carbon Fiber Fillers by Lebedeva, Elena A, Ivanova, Elena V, Trukhinov, Denis K, Istomina, Tatiana S, Knyazev, Nikolay S, Malkin, Alexander I, Chechetkin, Victor A, Korotkov, Alexey N, Balasoiu, Maria, Astaf'eva, Svetlana A

“…With the rapid development of wireless communication technologies and the miniaturization trend in the electronics industry, the reduction of electromagnetic…”
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Atlantic Meridional Overturning Circulation During the Last Glacial Maximum by Lynch-Stieglitz, Jean, Adkins, Jess F, Curry, William B, Dokken, Trond, Hall, Ian R, Herguera, Juan Carlos, Hirschi, Joël J.-M, Ivanova, Elena V, Kissel, Catherine, Marchal, Olivier, Marchitto, Thomas M, McCave, I. Nicholas, McManus, Jerry F, Mulitza, Stefan, Ninnemann, Ulysses, Peeters, Frank, Yu, Ein-Fen, Zahn, Rainer

“…The circulation of the deep Atlantic Ocean during the height of the last ice age appears to have been quite different from today. We review observations…”
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Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes by Lizotte, Patrick H, Ivanova, Elena V, Awad, Mark M, Jones, Robert E, Keogh, Lauren, Liu, Hongye, Dries, Ruben, Almonte, Christina, Herter-Sprie, Grit S, Santos, Abigail, Feeney, Nora B, Paweletz, Cloud P, Kulkarni, Meghana M, Bass, Adam J, Rustgi, Anil K, Yuan, Guo-Cheng, Kufe, Donald W, Jänne, Pasi A, Hammerman, Peter S, Sholl, Lynette M, Hodi, F Stephen, Richards, William G, Bueno, Raphael, English, Jessie M, Bittinger, Mark A, Wong, Kwok-Kin

“…Immune checkpoint blockade improves survival in a subset of patients with non-small-cell lung cancer (NSCLC), but robust biomarkers that predict response to…”
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Microbial Communities of Flor Velums and the Genetic Stability of Flor Yeasts Used for a Long Time for the Industrial Production of Sherry-like Wines by Mardanov, Andrey V, Gruzdev, Eugeny V, Beletsky, Alexey V, Ivanova, Elena V, Shalamitskiy, Maksim Yu, Tanashchuk, Tatiana N, Ravin, Nikolai V

“…Flor yeast strains represent a specialized group of Saccharomyces cerevisiae yeasts used for the production of sherry-like wines by biological wine aging. We…”
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Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis by Koistinen, Niina A, Edlund, Anna K, Menon, Preeti K, Ivanova, Elena V, Bacanu, Smaranda, Iverfeldt, Kerstin

“…Fe65 is an adaptor protein involved in both processing and signaling of the Alzheimer-associated amyloid-β precursor protein, APP. Here, the subcellular…”
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Genome sequence data and properties of Bifidobacterium bifidum strain ICIS-504 isolated from multispecies bifidobacterial community by Andryuschenko, Sergey V., Ivanova, Elena V., Perunova, Natalia B., Bukharin, Oleg V., Zdvizhkova, Irina A.

“…This report presents the data on the draft genome sequence of Bifidobacterium bifidum strain ICIS-504. The strain, isolated from the intestine of a 41-year-old…”
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Anchoring of FRET Sensors-A Requirement for Spatiotemporal Resolution by Ivanova, Elena V, Figueroa, Ricardo A, Gatsinzi, Tom, Hallberg, Einar, Iverfeldt, Kerstin

“…FRET biosensors have become a routine tool for investigating mechanisms and components of cell signaling. Strategies for improving them for particular…”
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TRAIL resistance in human neuroblastoma SK-N-AS cells is dependent on protein kinase C and involves inhibition of caspase-3 proteolytic processing by Gatsinzi, Tom, Ivanova, Elena V., Iverfeldt, Kerstin

“…Neuroblastoma is the most common solid extracranial cancer form in childhood with an etiology that is mostly unknown. Although tumor necrosis factor-related…”
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Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism by Lee, Jong-Min, Ivanova, Elena V, Seong, Ihn Sik, Cashorali, Tanya, Kohane, Isaac, Gusella, James F, MacDonald, Marcy E

“…The Huntington's disease (HD) CAG repeat, encoding a polymorphic glutamine tract in huntingtin, is inversely correlated with cellular energy level, with…”
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