Search Results - "Ivan de Ávila, Renato"

Toxicological evaluation of Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark extract: Acute and subchronic studies in mice by Ávila, Renato Ivan de, Ferreira, Camila Carvalho, Alvarenga, Cátia Belo Mattos, Vieira, Marcelo de Sousa, Cortez, Alane Pereira, Batista, Aline Carvalho, Costa, Elson Alves, Valadares, Marize Campos

“…This study evaluated the safety of Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark hydroalcoholic extract (LPE) through acute and subchronic toxicological…”
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LQFM184: A Novel Wide Ultraviolet Radiation Range Absorber Compound by Vinhal, Daniela C., Ivan de Ávila, Renato, Rodrigues, Thaisângela L., Silva, Andressa K., Moreira, Larissa C., Valadares, Marize C., Luzin, Rangel M., Lião, Luciano M., Gil, Eric de S., Vaz, Boniek G., Assis, Rogério J., Gonçalves, Pablo J., Isaac, Vera, da Cunha, Luiz C., Menegatti, Ricardo

“…The use of sunscreen has become an indispensable daily routine since UV radiation is a critical environmental stress factors for human skin. This study focused…”
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4-Nerolidylcatechol: apoptosis by mitochondrial mechanisms with reduction in cyclin D1 at G0/G1 stage of the chronic myelogenous K562 cell line by Benfica, Polyana Lopes, Ávila, Renato Ivan de, Rodrigues, Bruna dos Santos, Cortez, Alane Pereira, Batista, Aline Carvalho, Gaeti, Marilisa Pedroso Nogueira, Lima, Eliana Martins, Rezende, Kênnia Rocha, Valadares, Marize Campos

“…Context: 4-Nerolidylcatechol (4-NRC) has showed antitumor potential through apoptosis. However, its apoptotic mechanisms are still unclear, especially in…”
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Impact of Bariatric Surgery on Patients from Goiás, Brazil, Using the BAROS Method – A Preliminary Study by Ribeiro, Emmeline Flor, de Ávila, Renato Ivan, de Sousa Santos, Rosineide Ribeiro, Garrote, Clévia Ferreira Duarte

“…Introduction: As obesity is currently a major public health problem, bariatric surgery has been widely indicated due to the difficulties involved in the…”
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Antifungal potential of punicalagin against Cryptococcus neoformans species complex by Silva, Thaísa Cristina, Zara, Ana Laura de Sene Amâncio, Sá, Fabyola Amaral da Silva, Bara, Maria Teresa Freitas, Ávila, Renato Ivan de, Costa, Carolina Rodrigues, Valadares, Marize Campos, Santos, Andressa Santana Dos, Freitas, Vivianny Aparecida Queiroz, Silva, Maria do Rosário Rodrigues

“…This study evaluated the antifungal activity and cytotoxicity profile of the ellagitannin punicalagin, a compound extracted from the L. pacari A. St.-Hil…”
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Adjuvants in fungicide formulations can be skin sensitizers and cause different types of cell stress responses by de Ávila, Renato Ivan, Carreira Santos, Sofía, Siino, Valentina, Levander, Fredrik, Lindstedt, Malin, Zeller, Kathrin S.

“…New approaches based on -omics technologies can identify biomarkers and processes regulated in response to xenobiotics, and thus support toxicological risk…”
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A proteomics dataset capturing myeloid cell responses upon cellular exposure to fungicides, adjuvants and fungicide formulations by de Ávila, Renato Ivan, Carreira Santos, Sofía, Siino, Valentina, Levander, Fredrik, Lindstedt, Malin, Zeller, Kathrin S.

“…Dendritic cells are the sentinels of the immune system, linking the innate and adaptive immune response. Myeloid and dendritic cell models have been…”
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LQFM030 reduced Ehrlich ascites tumor cell proliferation and VEGF levels by da Mota, Mariana Flavia, de Carvalho, Flávio Silva, de Ávila, Renato Ivan, de Ávila, Paulo Henrique Marcelino, Cortez, Alane Pereira, Menegatti, Ricardo, Sabino, José Ricardo, dos Santos, Thais Rosa Marques, Gomes, Sandro Antônio, da Cunha, Luiz Carlos, Valadares, Marize Campos

“…This study reports the biological properties of LQFM030 in vivo, a molecular simplification of the compound nutlin-1. Ehrlich ascites tumor (EAT)-bearing mice…”
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Mucoadhesive formulation of Bidens pilosa L. (Asteraceae) reduces intestinal injury from 5-fluorouracil-induced mucositis in mice by de Ávila, Paulo Henrique Marcelino, de Ávila, Renato Ivan, Dos Santos Filho, Edvande Xavier, Cunha Bastos, Carla Caroline, Batista, Aline Carvalho, Mendonça, Elismauro Francisco, Serpa, Raphael Caixeta, Marreto, Ricardo Neves, da Cruz, Andrezza Furquim, Lima, Eliana Martins, Valadares, Marize Campos

“…Gastrointestinal mucositis induced during cancer treatment is considered a serious dose-limiting side effect of chemotherapy and/or radiotherapy. Frequently,…”
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New pyrazole derivative 5‐[1‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole: synthesis and assessment of some biological activities by Oliveira, Lanussy Porfiro, Silva, Daiany Priscilla Bueno, Florentino, Iziara Ferreira, Fajemiroye, James Oluwagbamigbe, Oliveira, Thiago Sardinha, Marcelino, Renato Ivan de Ávila, Pazini, Francine, Lião, Luciano Morais, Ghedini, Paulo César, Moura, Soraia Santana, Valadares, Marize Campos, Carvalho, Verônica Vale, Vaz, Boniek Gontijo, Menegatti, Ricardo, Costa, Elson Alves

“…The molecular modification and synthesis of compounds is vital to discovering drugs with desirable pharmacological and toxicity profiles. In response to…”
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Use of Bidens pilosa L. (Asteraceae) and Curcuma longa L. (Zingiberaceae) to treat intestinal mucositis in mice: Toxico-pharmacological evaluations by Bastos, Carla Caroline Cunha, Ávila, Paulo Henrique Marcelino de, Filho, Edvande Xavier Dos Santos, Ávila, Renato Ivan de, Batista, Aline Carvalho, Fonseca, Simone Gonçalves, Lima, Eliana Martins, Marreto, Ricardo Neves, Mendonça, Elismauro Francisco de, Valadares, Marize Campos

“…Several studies towards the development of an effective treatment for intestinal mucositis have been reported, since this condition represents a major problem…”
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Campomanesia adamantium (Myrtaceae) fruits protect HEPG2 cells against carbon tetrachloride-induced toxicity by de Oliveira Fernandes, Thaís, de Ávila, Renato Ivan, de Moura, Soraia Santana, de Almeida Ribeiro, Gerlon, Naves, Maria Margareth Veloso, Valadares, Marize Campos

“…(Myrtaceae) is an antioxidant compounds-rich Brazilian fruit popularly known as . In view of this, it was evaluated the hepatoprotective effects of pulp (GPE)…”
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Non-animal approaches for photoallergenicity safety assessment: Needs and perspectives for the toxicology for the 21st century by de Ávila, Renato Ivan, Aleksic, Maja, Zhu, Bin, Li, Jin, Pendlington, Ruth, Valadares, Marize Campos

“…Certain chemicals and/or their byproducts are photoactivated by UV/VIS and trigger a dermal allergenic response, clinically recognized as photoallergic contact…”
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The 21st Century movement within the area of skin sensitization assessment: From the animal context towards current human-relevant in vitro solutions by de Ávila, Renato Ivan, Lindstedt, Malin, Valadares, Marize Campos

“…In a regulatory context, skin sensitization hazard and risk evaluations of manufactured products and their ingredients (e.g. cosmetics) are mandatory in…”
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Multicompartimental Nanoparticles for Co-Encapsulation and Multimodal Drug Delivery to Tumor Cells and Neovasculature by Mendes, Lívia Palmerston, Gaeti, Marilisa Pedroso Nogueira, de Ávila, Paulo Henrique Marcelino, de Sousa Vieira, Marcelo, dos Santos Rodrigues, Bruna, de Ávila Marcelino, Renato Ivan, dos Santos, Lílian Cristina Rosa, Valadares, Marize Campos, Lima, Eliana Martins

“…ABSTRACT Purpose The purpose of this work was the development of a multicompartimental nanocarrier for the simultaneous encapsulation of paclitaxel (PTX) and…”
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In vitro characterisation of a novel rubber contact allergen in protective gloves by de Ávila, Renato Ivan, Ljungberg Silic, Linda, Carreira-Santos, Sofía, Merényi, Gábor, Bergendorff, Ola, Zeller, Kathrin S

“…Allergic contact dermatitis (ACD) from protective gloves is often caused by rubber additives, such as accelerators. However, while accelerator-free rubber…”
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Brazil Moves Toward the Replacement of Animal Experimentation by de Ávila, Renato Ivan, Valadares, Marize Campos

“…In Brazil, efforts towards the regulatory acceptance and implementation of innovative methods to replace experimental animal use in various fields began to…”
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Development of a novel ex vivo model for chemical ocular toxicity assessment and its applicability for hair straightening products by Rodrigues da Penha, Jaqueline, Garcia da Silva, Artur Christian, de Ávila, Renato Ivan, Valadares, Marize Campos

“…This study developed an air-liquid interface (ALI) corneal model using explants bovine eyes for ocular toxicity assessment of ten chemicals and seven hair…”
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An integrated transcriptomic- and proteomic-based approach to evaluate the human skin sensitization potential of glyphosate and its commercial agrochemical formulations by Lindberg, Tim, de Ávila, Renato Ivan, Zeller, Kathrin S., Levander, Fredrik, Eriksson, Dennis, Chawade, Aakash, Lindstedt, Malin

“…We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing…”
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Análise dos resíduos farmacêuticos recebidos em práticas educativas para promoção do descarte consciente de medicamentos vencidos ou em desuso no estado de Goiás, Brasil by Da Silva, Gabriela Soares, Ferreira, João Paulo Araújo, Ferreira, Lorena Neves, Camargo, Laysa Augusta de, Cunha, Bruna Paula da, Rivello, Bárbara Gonçalves, Ávila, Renato Ivan de

“…Introdução: Anualmente, entre 10 e 28 mil toneladas de medicamentos são inadequadamente descartados no ambiente pelos consumidores brasileiros, tratando-se de…”
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