Search Results - "Ivan Valkadinov"

Tofersen decreases neurofilament levels supporting the pathogenesis of the SOD1 p.D91A variant in amyotrophic lateral sclerosis patients by Weishaupt, Jochen H., Körtvélyessy, Péter, Schumann, Peggy, Valkadinov, Ivan, Weyen, Ute, Hesebeck-Brinckmann, Jasper, Weishaupt, Kanchi, Endres, Matthias, Andersen, Peter M., Regensburger, Martin, Dreger, Marie, Koch, Jan C., Conrad, Julian, Meyer, Thomas

“…Background Since the antisense oligonucleotide tofersen has recently become available for the treatment of amyotrophic lateral sclerosis (ALS) caused by…”
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Quadruple genetic variants in a sporadic ALS patient by Yilmaz, Rüstem, Weishaupt, Kanchi, Valkadinov, Ivan, Knehr, Antje, Brenner, David, Weishaupt, Jochen H.

“…Objectives Due to upcoming gene‐specific therapy approaches for ALS patients, understanding familial and sporadic ALS genetics is becoming increasingly…”
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Rare case of ameloblastoma with pulmonary metastases by Valkadinov, Ivan, Conev, Nikolay, Dzhenkov, Dian, Donev, Ivan

“…Ameloblastoma is a rare low-grade odontogenic tumor of epithelial origin. The World Health Organization (WHO) has defined malignant ameloblastoma (MA) as a…”
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Harmonic Shears in the Surgical Treatment of Laryngomalacia by Sapundzhiev, Nikolay R, Nikiforova, Lora T, Stoyanov, George S, Valkadinov, Ivan, Genova, Petya, Platikanov, Vilian

“…IntroductionLaryngomalacia (LM) is a condition that is clinically diagnosed in the pediatric period with inspiratory stridor and is caused by a congenital or…”
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Clinical and patient‐reported outcomes and neurofilament response during tofersen treatment in SOD1‐related ALS—A multicenter observational study over 18months by Meyer, Thomas, Schumann, Peggy, Weydt, Patrick, Petri, Susanne, Weishaupt, Jochen H, Weyen, Ute, Koch, Jan C, Günther, René, Regensburger, Martin, Boentert, Matthias, Wiesenfarth, Maximilian, Koc, Yasemin, Kolzarek, Felix, Kettemann, Dagmar, Norden, Jenny, Bernsen, Sarah, Elmas, Zeynep, Conrad, Julian, Valkadinov, Ivan, Vidovic, Maximilian, Dorst, Johannes, Ludolph, Albert C, Jasper Hesebeck‐Brinckmann, Spittel, Susanne, Münch, Christoph, Maier, André, Körtvélyessy, Péter

“…Introduction/AimsIn amyotrophic lateral sclerosis (ALS) caused by SOD1 mutations (SOD1‐ALS), tofersen received accelerated approval in the United States and is…”
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Clinical and patient‐reported outcomes and neurofilament response during tofersen treatment in SOD1‐related ALS—A multicenter observational study over 18 months by Meyer, Thomas, Schumann, Peggy, Weydt, Patrick, Petri, Susanne, Weishaupt, Jochen H., Weyen, Ute, Koch, Jan C., Günther, René, Regensburger, Martin, Boentert, Matthias, Wiesenfarth, Maximilian, Koc, Yasemin, Kolzarek, Felix, Kettemann, Dagmar, Norden, Jenny, Bernsen, Sarah, Elmas, Zeynep, Conrad, Julian, Valkadinov, Ivan, Vidovic, Maximilian, Dorst, Johannes, Ludolph, Albert C., Hesebeck‐Brinckmann, Jasper, Spittel, Susanne, Münch, Christoph, Maier, André, Körtvélyessy, Péter

“…Introduction/Aims In amyotrophic lateral sclerosis (ALS) caused by SOD1 mutations (SOD1‐ALS), tofersen received accelerated approval in the United States and…”
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Frequency of C9orf72 and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers by Yilmaz, Rüstem, Grehl, Torsten, Eckrich, Lukas, Marschalkowski, Ines, Weishaupt, Kanchi, Valkadinov, Ivan, Simic, Melita, Brenner, David, Andersen, Peter M., Wolf, Joachim, Weishaupt, Jochen H.

“…Background: ALS patients with a negative family history (sporadic ALS, SALS) represent more than 90% of all ALS cases. In light of the gene-specific therapies…”
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PSEN1/SLC20A2 double mutation causes early-onset Alzheimer’s disease and primary familial brain calcification co-morbidity by Hebestreit, Sophie, Schwahn, Janine, Sandikci, Vesile, Maros, Mate E., Valkadinov, Ivan, Yilmaz, Rüstem, Eckrich, Lukas, Loghmani, Seyed Babak, Lesch, Hendrik, Conrad, Julian, Wenz, Holger, Ebert, Anne, Brenner, David, Weishaupt, Jochen H.

“…Primary familial brain calcification (PFBC; formerly Fahr’s disease) and early-onset Alzheimer’s disease (EOAD) may share partially overlapping pathogenic…”
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Effects of tofersen treatment in patients with SOD1-ALS in a “real-world” setting – a 12-month multicenter cohort study from the German early access program by Wiesenfarth, Maximilian, Dorst, Johannes, Brenner, David, Elmas, Zeynep, Parlak, Özlem, Uzelac, Zeljko, Kandler, Katharina, Mayer, Kristina, Weiland, Ulrike, Herrmann, Christine, Schuster, Joachim, Freischmidt, Axel, Müller, Kathrin, Siebert, Reiner, Bachhuber, Franziska, Simak, Tatiana, Günther, Kornelia, Fröhlich, Elke, Knehr, Antje, Regensburger, Martin, German, Alexander, Petri, Susanne, Grosskreutz, Julian, Klopstock, Thomas, Reilich, Peter, Schöberl, Florian, Hagenacker, Tim, Weyen, Ute, Günther, René, Vidovic, Maximilian, Jentsch, Martin, Haarmeier, Thomas, Weydt, Patrick, Valkadinov, Ivan, Hesebeck-Brinckmann, Jasper, Conrad, Julian, Weishaupt, Jochen Hans, Schumann, Peggy, Körtvélyessy, Peter, Meyer, Thomas, Ruf, Wolfgang Philipp, Witzel, Simon, Senel, Makbule, Tumani, Hayrettin, Ludolph, Albert Christian

“…In April 2023, the antisense oligonucleotide tofersen was approved by the U.S. Food and Drug Administration (FDA) for treatment of SOD1-amyotrophic lateral…”
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Effects of tofersen treatment in patients with SOD1-ALS in a “real-world” setting – a 12-month multicenter cohort study from the German early access programResearch in context by Maximilian Wiesenfarth, Johannes Dorst, David Brenner, Zeynep Elmas, Özlem Parlak, Zeljko Uzelac, Katharina Kandler, Kristina Mayer, Ulrike Weiland, Christine Herrmann, Joachim Schuster, Axel Freischmidt, Kathrin Müller, Reiner Siebert, Franziska Bachhuber, Tatiana Simak, Kornelia Günther, Elke Fröhlich, Antje Knehr, Martin Regensburger, Alexander German, Susanne Petri, Julian Grosskreutz, Thomas Klopstock, Peter Reilich, Florian Schöberl, Tim Hagenacker, Ute Weyen, René Günther, Maximilian Vidovic, Martin Jentsch, Thomas Haarmeier, Patrick Weydt, Ivan Valkadinov, Jasper Hesebeck-Brinckmann, Julian Conrad, Jochen Hans Weishaupt, Peggy Schumann, Peter Körtvélyessy, Thomas Meyer, Wolfgang Philipp Ruf, Simon Witzel, Makbule Senel, Hayrettin Tumani, Albert Christian Ludolph

“…Background: In April 2023, the antisense oligonucleotide tofersen was approved by the U.S. Food and Drug Administration (FDA) for treatment of SOD1-amyotrophic…”
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Rare case of ameloblastoma with pulmonary metastases by Valkadinov, Ivan, Conev, Nikolay, Dzhenkov, Dian, Donev, Ivan

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