Search Results - "Ivan, R."
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A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins
Published in Nature chemistry (01-02-2013)“…The ideal fluorescent probe for bioimaging is bright, absorbs at long wavelengths and can be implemented flexibly in living cells and in vivo . However, the…”
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2
Targeting GLP-1 receptor trafficking to improve agonist efficacy
Published in Nature communications (23-04-2018)“…Glucagon-like peptide-1 receptor (GLP-1R) activation promotes insulin secretion from pancreatic beta cells, causes weight loss, and is an important…”
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3
A semi-synthetic organism with an expanded genetic alphabet
Published in Nature (London) (15-05-2014)“…Triphosphates of hydrophobic nucleotides d5SICS and dNaM are imported into Escherichia coli by an exogenous algal nucleotide triphosphate transporter and…”
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4
Metabolic Incorporation of Azide Functionality into Cellular RNA
Published in Chembiochem : a European journal of chemical biology (17-11-2016)“…Real‐time tracking of RNA expression can provide insight into the mechanisms used to generate cellular diversity, as well as help determine the underlying…”
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5
Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells
Published in PloS one (10-03-2015)“…Epithelial-mesenchymal transition (EMT) is associated with loss of the cell-cell adhesion molecule E-cadherin and disruption of cell-cell junctions as well as…”
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The Formin Daam1 and Fascin Directly Collaborate to Promote Filopodia Formation
Published in Current biology (22-07-2013)“…Filopodia are slender cellular protrusions that dynamically extend and retract to facilitate directional cell migration, pathogen sensing, and cell-cell…”
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7
Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
Published in Nature (London) (20-02-2014)“…The Tet family of dioxygenase enzymes convert 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine, which has an effect on gene…”
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Mechanism and timing of Mcm2–7 ring closure during DNA replication origin licensing
Published in Nature structural & molecular biology (01-03-2017)“…smFRET analysis and colocalization spectroscopy reveal the mechanism of DNA entry into the Mcm2–7 helicase ring during replication origin licensing. The…”
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9
Journey Describing Applications of Oxone in Synthetic Chemistry
Published in Chemical reviews (08-05-2013)“…Hussain et al examine the applications of oxone in synthetic chemistry…”
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10
The galectin lattice at a glance
Published in Journal of cell science (01-07-2015)“…Galectins are a family of widely expressed β-galactoside-binding lectins in metazoans. The 15 mammalian galectins have either one or two conserved carbohydrate…”
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11
Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA
Published in Genome research (01-07-2021)“…Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and…”
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12
Evaluation of Fluorophores to Label SNAP-Tag Fused Proteins for Multicolor Single-Molecule Tracking Microscopy in Live Cells
Published in Biophysical journal (19-08-2014)“…Single-molecule tracking has become a widely used technique for studying protein dynamics and their organization in the complex environment of the cell. In…”
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Nondestructive enzymatic deamination enables single-molecule long-read amplicon sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
Published in Genome research (01-02-2021)“…The predominant methodology for DNA methylation analysis relies on the chemical deamination by sodium bisulfite of unmodified cytosine to uracil to permit the…”
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14
Development of SNAP-Tag Fluorogenic Probes for Wash-Free Fluorescence Imaging
Published in Chembiochem : a European journal of chemical biology (19-09-2011)“…The ability to specifically attach chemical probes to individual proteins represents a powerful approach to the study and manipulation of protein function in…”
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15
Clathrin-independent pathways do not contribute significantly to endocytic flux
Published in eLife (17-09-2014)“…Several different endocytic pathways have been proposed to function in mammalian cells. Clathrin-coated pits are well defined, but the identity, mechanism and…”
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Transient Accumulation of 5-Carboxylcytosine Indicates Involvement of Active Demethylation in Lineage Specification of Neural Stem Cells
Published in Cell reports (Cambridge) (12-06-2014)“…5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to…”
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A Sensitive Approach to Map Genome-wide 5-Hydroxymethylcytosine and 5-Formylcytosine at Single-Base Resolution
Published in Molecular cell (19-02-2015)“…Mapping genome-wide 5-hydroxymethylcytosine (5hmC) and 5-formylcytosine (5fC) at single-base resolution is important to understand their biological functions…”
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18
Base modifications affecting RNA polymerase and reverse transcriptase fidelity
Published in Nucleic acids research (20-06-2018)“…Abstract Ribonucleic acid (RNA) is capable of hosting a variety of chemically diverse modifications, in both naturally-occurring post-transcriptional…”
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Quantification of the impact of endometriosis symptoms on health-related quality of life and work productivity
Published in Fertility and sterility (01-07-2011)“…Objective To quantify the impact of endometriosis-related symptoms on physical and mental health status, health-related quality of life, and work-related…”
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Optimisation of PV-wind-diesel-battery stand-alone systems to minimise cost and maximise human development index and job creation
Published in Renewable energy (01-08-2016)“…In this paper we show a multi-objective evolutionary algorithm (MOEA) for the optimisation of stand-alone (off-grid) hybrid systems…”
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