Search Results - "Iulia, I"

Catalyst-Controlled C–O versus C–N Allylic Functionalization of Terminal Olefins by Strambeanu, Iulia I, White, M. Christina

“…The divergent synthesis of syn-1,2-aminoalcohol or syn-1,2-diamine precursors from a common terminal olefin has been accomplished using a combination of…”
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The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future by Mennen, Steven M, Alhambra, Carolina, Allen, C. Liana, Barberis, Mario, Berritt, Simon, Brandt, Thomas A, Campbell, Andrew D, Castañón, Jesús, Cherney, Alan H, Christensen, Melodie, Damon, David B, Eugenio de Diego, J, García-Cerrada, Susana, García-Losada, Pablo, Haro, Rubén, Janey, Jacob, Leitch, David C, Li, Ling, Liu, Fangfang, Lobben, Paul C, MacMillan, David W. C, Magano, Javier, McInturff, Emma, Monfette, Sebastien, Post, Ronald J, Schultz, Danielle, Sitter, Barbara J, Stevens, Jason M, Strambeanu, Iulia I, Twilton, Jack, Wang, Ke, Zajac, Matthew A

“…High-throughput experimentation (HTE) has revolutionized the pharmaceutical industry, most notably allowing for rapid screening of compound libraries against…”
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Aerobic Linear Allylic C–H Amination: Overcoming Benzoquinone Inhibition by Pattillo, Christopher C, Strambeanu, Iulia I, Calleja, Pilar, Vermeulen, Nicolaas A, Mizuno, Tomokazu, White, M. Christina

“…An efficient aerobic linear allylic C–H amination reaction is reported under palladium­(II)/bis-sulfoxide/Brønsted base catalysis. The reaction operates under…”
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Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation by Hendrick, Charles E., Jorgensen, Jeff R., Chaudhry, Charu, Strambeanu, Iulia I., Brazeau, Jean-Francois, Schiffer, Jamie, Shi, Zhicai, Venable, Jennifer D., Wolkenberg, Scott E.

“…A platform to accelerate optimization of proteolysis targeting chimeras (PROTACs) has been developed using a direct-to-biology (D2B) approach with a focus on…”
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Privileged crosstalk between TRPV1 channels and mitochondrial calcium shuttling machinery controls nociception by Nita, Iulia I., Caspi, Yaki, Gudes, Sagi, Fishman, Dimitri, Lev, Shaya, Hersfinkel, Michal, Sekler, Israel, Binshtok, Alexander M.

“…The nociceptive noxious heat-activated receptor - TRPV1, conducts calcium and sodium, thus producing a depolarizing receptor potential, leading to activation…”
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The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretion by Nita, Iulia I, Hershfinkel, Michal, Fishman, Daniel, Ozeri, Eyal, Rutter, Guy A, Sensi, Stefano L, Khananshvili, Daniel, Lewis, Eli C, Sekler, Israel

“…Mitochondria mediate dual metabolic and Ca(2+) shuttling activities. While the former is required for Ca(2+) signalling linked to insulin secretion, the role…”
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Pancreatic β‐cell Na+ channels control global Ca2+ signaling and oxidative metabolism by inducing Na+ and Ca2+ responses that are propagated into mitochondria by Nita, Iulia I., Hershfinkel, Michal, Kantor, Chase, Rutter, Guy A., Lewis, Eli C., Sekler, Israel

“…Communication between the plasma membrane and mitochondria is essential for initiating the Ca2+ and metabolic signals required for secretion in β cells…”
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A crosstalk between Na+ channels, Na+ /K+ pump and mitochondrial Na+ transporters controls glucose-dependent cytosolic and mitochondrial Na+ signals by Nita, Iulia I, Hershfinkel, Michal, Lewis, Eli C, Sekler, Israel

“…Graphical abstract…”
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Differential signaling patterns of stimulated bone marrow-derived dendritic cells under α1-antitrypsin-enriched conditions by Ozeri, Eyal, Rider, Peleg, Rigbi, Shoham, Shahaf, Galit, Nita, Iulia I., Sekler, Israel, Lewis, Eli C., Schuster, Ronen

“…•α1-antitrypsin modulates transduction of multiple inflammatory signaling pathways.•Stimulated calcium flux is attenuated in the presence of…”
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Convergent Synthesis of the NS5B Inhibitor GSK8175 Enabled by Transition Metal Catalysis by Arrington, Kenneth, Barcan, Gregg A, Calandra, Nicholas A, Erickson, Greg A, Li, Ling, Liu, Li, Nilson, Mark G, Strambeanu, Iulia I, VanGelder, Kelsey F, Woodard, John L, Xie, Shiping, Allen, C. Liana, Kowalski, John A, Leitch, David C

“…A convergent eight-stage synthesis of the boron-containing NS5B inhibitor GSK8175 is described. The previous route involves 13 steps in a completely linear…”
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Anomalous Inverse Hysteresis of Phase Transition in Thermosensitive Dextran-graft-PNIPAM Copolymer/Au Nanoparticles Hybrid Nanosystem by Yeshchenko, Oleg A, Naumenko, Antonina P, Kutsevol, Nataliya V, Maskova, Daria O, Harahuts, Iulia I, Chumachenko, Vasyl A, Marinin, Andrey I

“…An anomalous inverse hysteresis behavior of the thermally induced LCST structural phase transition in dextran-graft-PNIPAM copolymer macromolecules with Au…”
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Laser-driven structural transformations in dextran-graft-PNIPAM copolymer/Au nanoparticles hybrid nanosystem: the role of plasmon heating and attractive optical forces by Yeshchenko, Oleg A, Naumenko, Antonina P, Kutsevol, Nataliya V, Harahuts, Iulia I

“…Laser induced structural transformations in a dextran grafted-poly( N -isopropylacrylamide) copolymer/Au nanoparticles (D- g -PNIPAM/AuNPs) hybrid nanosystem…”
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Enabling Deoxygenative C(sp2)‑C(sp3) Cross-Coupling for Parallel Medicinal Chemistry by Liu, Wei, Mulhearn, James, Hao, Bo, Cañellas, Santiago, Last, Stefaan, Gómez, José Enrique, Jones, Alexander, De Vera, Alexander, Kumar, Kiran, Rodríguez, Raquel, Van Eynde, Lars, Strambeanu, Iulia I., Wolkenberg, Scott E.

“…Herein we report the development of an automated deoxygenative C­(sp2)-C­(sp3) coupling of aryl bromide with alcohols to enable parallel medicinal chemistry…”
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Transcription-facilitating histone chaperons interact with genomic and synthetic G4 structures by Pavlova, Iulia I., Tsvetkov, Vladimir B., Isaakova, Ekaterina A., Severov, Vyacheslav V., Khomyakova, Ekaterina A., Lacis, Ivan A., Lazarev, Vassilii N., Lagarkova, Maria A., Pozmogova, Galina E., Varizhuk, Anna M.

“…Affinity for G-quadruplex (G4) structures may be a common feature of transcription-facilitating histone chaperons (HCs). This assumption is based on previous…”
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Scalable and Chemoselective Synthesis of γ‑Keto Esters and Acids via Pd-Catalyzed Carbonylation of Cyclic β‑Chloro Enones by Kaplan, Justin M, Hruszkewycz, Damian P, Strambeanu, Iulia I, Nunn, Christopher J, VanGelder, Kelsey F, Dunn, Anna L, Wozniak, Derek I, Dobereiner, Graham E, Leitch, David C

“…The Pd-catalyzed carbonylation of cyclic β-chloro enones using simple phosphine ligands is described. Screening identified P­(Me)­(t-Bu)2 as the most general…”
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Prospective Analysis of Discordant Results Between Fibromax® and Fibroscan® in Patients with HCV Compensated Liver Cirrhosis before 3D Antiviral Therapy Initiation by Gheorghe, Liliana, Iacob, Speranta, Prelipcean, Cristina Cijevschi, Trifan, Anca, Stanciu, Carol, Sporea, Ioan, Sirli, Roxana, Curescu, Manuela, Brisc, Ciprian, Mihai, Catalina, Alexandrescu, Luana, Sandulescu, Larisa D, Goldis, Adrian, Arama, Victoria, Caruntu, Florin, Hara, Livia, Rogoveanu, Ion, Diculescu, Mircea, Gheorghe, Cristian, Seicean, Andrada, Iacob, Razvan, Simionov, Iulia I, Vadan, Roxana, Pirvulescu, Iuliana, Pietrareanu, Corina

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Predictors of Liver Stiffness Regression after SVR in Cirrhotic Patients Treated with 3D Regimen by Iacob, Speranta, Gheorghe, Liliana, Prelipcean, Cristina Cijevschi, Trifan, Anca, Stanciu, Carol, Sporea, Ioan, Sirli, Roxana, Curescu, Manuela, Brisc, Ciprian, Mihai, Catalina, Alexandrescu, Luana, Sandulescu, Larisa D, Goldis, Adrian, Arama, Victoria, Caruntu, Florin, Hara, Livia, Rogoveanu, Ion, Diculescu, Mircea, Iacob, Razvan, Gheorghe, Cristian, Seicean, Andrada, Simionov, Iulia I, Vadan, Roxana, Pirvulescu, Iuliana, Pietrareanu, Corina

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Ergo@Home Guideline – a Tool for Working from Home Using Information Technology, in Pandemic by Popescu, Florina, Păuncu, Elena-Ana, Drăgoi, Iulia I., Tomescu, Mirela C., Cristodor, Patricia, Teodoru, Adrian, Lăzurean, Pompilia C., Lazurean, Adrian, Capotescu, Sebastian, Mohora, Irina, Draghici, Anca

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The BRIGHTEN Program: Implementation and Evaluation of a Program to Bridge Resources of an Interdisciplinary Geriatric Health Team via Electronic Networking by Emery, Erin E, Lapidos, Stan, Eisenstein, Amy R, Ivan, Iulia I, Golden, Robyn L

“…Purpose: To demonstrate the feasibility of the BRIGHTEN Program (Bridging Resources of an Interdisciplinary Geriatric Health Team via Electronic Networking),…”
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OSMOTIC PRESSURE INFLUENCE ON THE VEGETABLE CHIPS DEHYDRATION PROCESS by LILIANA I. MIHALCEA, IULIA I. BLEOANCĂ, CĂTĂLINA M. MIHAI, DANIELA D. BORDA

“…The low fruit and vegetable consumption identified by the World Health Organization is a significant factor for adverse health consequences, like obesity and…”
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