Search Results - "Itzstein, Cecile"

The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts by Destaing, Olivier, Sanjay, Archana, Itzstein, Cecile, Horne, William C, Toomre, Derek, De Camilli, Pietro, Baron, Roland

“…Podosomes are dynamic actin-rich structures composed of a dense F-actin core surrounded by a cloud of more diffuse F-actin. Src performs one or more unique…”
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The skeleton: a multi-functional complex organ. The role of key signalling pathways in osteoclast differentiation and in bone resorption by Mellis, David J, Itzstein, Cecile, Helfrich, Miep H, Crockett, Julie C

“…Osteoclasts are the specialised cells that resorb bone matrix and are important both for the growth and shaping of bones throughout development as well as…”
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The regulation of osteoclast function and bone resorption by small GTPases by Itzstein, Cecile, Coxon, Fraser P., Rogers, Michael J.

“…Osteoclasts are multinucleated cells that are responsible for resorption of bone, and increased activity of these cells is associated with several common bone…”
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Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy by Judson, Robert N, Gray, Stuart R, Walker, Claire, Carroll, Andrew M, Itzstein, Cecile, Lionikas, Arimantas, Zammit, Peter S, De Bari, Cosimo, Wackerhage, Henning

“…The aim of this study was to investigate the function of the Hippo pathway member Yes-associated protein (Yap, gene name Yap1) in skeletal muscle fibres in…”
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NMDA glutamate receptors are expressed by osteoclast precursors and involved in the regulation of osteoclastogenesis by Merle, Blandine, Itzstein, Cecile, Delmas, Pierre D., Chenu, Chantal

“…We previously identified functional N‐methyl‐d‐aspartate (NMDA) glutamate receptors in mature osteoclasts and demonstrated that they are involved in bone…”
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Identification and functional characterization of an Src homology domain 3 domain‐binding site on Cbl by Sanjay, Archana, Miyazaki, Tsuyoshi, Itzstein, Cecile, Purev, Enkhtsetseg, Horne, William C., Baron, Roland

“…Cbl is an adaptor protein and ubiquitin ligase that binds and is phosphorylated by the nonreceptor tyrosine kinase Src. We previously showed that the primary…”
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Active NMDA glutamate receptors are expressed by mammalian osteoclasts by Espinosa, Leon, Itzstein, Cécile, Cheynel, Hervé, Delmas, Pierre D., Chenu, Chantal

“…The N -methyl-D-aspartate (NMDA) glutamate receptor, widely distributed in the mammalian nervous system, has recently been identified in bone. In this study,…”
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A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss by Aoki, Kazuhiro, Saito, Hiroaki, Itzstein, Cecile, Ishiguro, Masaji, Shibata, Tatsuya, Blanque, Roland, Mian, Anower Hussain, Takahashi, Mariko, Suzuki, Yoshifumi, Yoshimatsu, Masako, Yamaguchi, Akira, Deprez, Pierre, Mollat, Patrick, Murali, Ramachandran, Ohya, Keiichi, Horne, William C, Baron, Roland

“…Activating receptor activator of NF-kappaB (RANK) and TNF receptor (TNFR) promote osteoclast differentiation. A critical ligand contact site on the TNFR is…”
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Specific Antagonists of NMDA Receptors Prevent Osteoclast Sealing Zone Formation Required for Bone Resorption by Itzstein, Cécile, Espinosa, Léon, Delmas, Pierre D., Chenu, Chantal

“…N-Methyl-d-aspartate (NMDA) glutamate receptors, widely distributed in the nervous system, have recently been identified in bone. They are expressed and are…”
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Molecular identification of NMDA glutamate receptors expressed in bone cells by Itzstein, Cécile, Cheynel, Hervé, Burt-Pichat, Brigitte, Merle, Blandine, Espinosa, Léon, Delmas, Pierre D., Chenu, Chantal

“…The N‐methyl‐D‐aspartate (NMDA) subtype of the glutamate receptor has recently been identified in bone, but the molecular composition of this receptor…”
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The skeleton: a multi-functional complex organ. The role of key signalling pathways in osteoclast differentiation and in bone resorption : The skeleton a multi-functional complex organ by MELLIS, David J, ITZSTEIN, Cecile, HELFRICH, Miep H, CROCKETT, Julie C

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Osteoclast formation in mouse co-cultures by Itzstein, Cecile, van 't Hof, Robert J

“…The murine co-culture assay is used to generate mature osteoclasts from bone marrow precursors by culturing them with osteoblasts that are stimulated with…”
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Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development by Gori, Francesca, Schipani, Ernestina, Demay, Marie B.

“…Fibromodulin, a keratan‐sulfate proteoglycan, was first isolated in articular cartilage and tendons. We have identified fibromodulin as a gene regulated during…”
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Absence of Evidence Is Not Evidence of Absence; Redundancy Blocks Determination of Cause and Effect by Chenu, Chantal, Itzstein, Cécile, Espinosa, Léon

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