Search Results - "Itzkowitz, S. H."

Stool DNA testing for the detection of colorectal neoplasia in patients with inflammatory bowel disease by Kisiel, J. B., Yab, T. C., Nazer Hussain, F. T., Taylor, W. R., Garrity‐Park, M. M., Sandborn, W. J., Loftus, E. V., Wolff, B. G., Smyrk, T. C., Itzkowitz, S. H., Rubin, D. T., Zou, H., Mahoney, D. W., Ahlquist, D. A.

“…Summary Background Current approaches to the detection of colorectal neoplasia associated with inflammatory bowel disease (IBD‐CRN) are suboptimal. Aim To test…”
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The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease by Torres, J, Palmela, C, Brito, H, Bao, X, Ruiqi, H, Moura-Santos, P, Pereira da Silva, J, Oliveira, A, Vieira, C, Perez, K, Itzkowitz, SH, Colombel, JF, Humbert, L, Rainteau, D, Cravo, M, Rodrigues, CM, Hu, J

“…Background Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal…”
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GLUT1 glucose transporter expression in colorectal carcinoma: A marker for poor prognosis by HABER, R. S, RATHAN, A, WEISER, K. R, PRITSKER, A, ITZKOWITZ, S. H, BODIAN, C, SLATER, G, WEISS, A, BURSTEIN, D. E

“…Malignant cells exhibit increased glycolytic metabolism, and in many cases increased glucose transporter gene expression. The authors hypothesized that GLUT1…”
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Mucin gene expression in colonic tissues and cell lines by OGATA, S, UEHARA, H, CHEN, A, ITZKOWITZ, S. H

“…Complementary DNA clones encoding four different mucin core peptides have been isolated. However, the expression of these mucin genes in the colon has not been…”
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Inflammatory bowel disease and cancer by Itzkowitz, S H

“…Colorectal cancer is a significant clinical problem for patients with long-standing ulcerative colitis and Crohn's disease. Traditional risk factors include…”
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Sialosyl-Tn antigen is prevalent and precedes dysplasia in ulcerative colitis: A retrospective case-control study by Itzkowitz, SH, Young, E, Dubois, D, Harpaz, N, Bodian, C, Chen, A, Sachar, DB

“…BACKGROUND & AIMS: Expression of the carbohydrate-associated sialosyl- Tn (STn) antigen has been correlated with carcinogenesis in sporadic colon cancer. This…”
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Mucin associated Tn and sialosyl-Tn antigen expression in colorectal polyps by Itzkowitz, S H, Bloom, E J, Lau, T S, Kim, Y S

“…Sialosyl-Tn antigen and its immediate precursor, Tn antigen, are carbohydrate structures associated with the earliest steps of mucin O-linked glycosylation…”
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Galectins: multipurpose carbohydrate-binding proteins implicated in tumor biology by Itzkowitz, S H

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Expression of MUC2 and MUC3 mRNA in human normal, malignant, and inflammatory intestinal tissues by Weiss, AA, Babyatsky, MW, Ogata, S, Chen, A, Itzkowitz, SH

“…MUC2 and MUC3 are prominent mucin genes expressed in the human intestine. Using in situ hybridization with RNA probes, we examined the cellular distribution of…”
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A comparison of three immunoperoxidase techniques for antigen detection in colorectal carcinoma tissues by Shi, ZR, Itzkowitz, SH, Kim, YS

“…We compared the streptavidin-peroxidase conjugate (SP) method of immunoperoxidase histochemistry to the unlabeled antibody (PAP) and avidin-biotin-peroxidase…”
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Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer by ITZKOWITZ, S. H, MEI YUAN, MONTGOMERY, C. K, KJELDSEN, T, TAKAHASHI, H. K, BIGBEE, W. L, KIM, Y. S

“…Mucin glycoproteins are major secretory products of the colon and contain O-linked oligosaccharides synthesized on a polypeptide backbone. The initial step in…”
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Mucin-associated sialosyl-Tn antigen expression in gastric cancer correlates with an adverse outcome by WERTHER, J. L, RIVERA-MACMURRAY, S, BBRUCKNER, H, TATEMATSU, M, ITZKOWITZ, S. H

“…The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed…”
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Tumor-associated sialylated antigens are constitutively expressed in normal human colonic mucosa by OGATA, S, HO, I, ANLI CHEN, DUBOIS, D, MAKLANSKY, J, ANIL SINGHAL, HAKOMORI, S.-I, ITZKOWITZ, S. H

“…Immunohistochemical studies have indicated that sialylated carbohydrate antigens such as sialyl-Tn, sialyl-Le(a), and sialyl-Le(x) are expressed in a…”
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Microsatellite instability in colitis associated colorectal cancer by ITZKOWITZ, S H

“…[...]the crucial difference relates to the choice and number of markers used in the various studies. Because MI testing has been so variable between…”
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Sialosyl-Tn antigen: initial report of a new marker of malignant progression in long-standing ulcerative colitis by Itzkowitz, S H, Marshall, A, Kornbluth, A, Harpaz, N, McHugh, J B, Ahnen, D, Sachar, D B

“…Expression of the mucin-associated carbohydrate antigen sialosyl-Tn (STn) correlates with malignant transformation in sporadic colonic neoplasms. The aim of…”
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Intestinalization of gastric signet ring cell carcinomas with progression by YAMACHIKA, T, INADA, K.-I, FUJIMITSU, Y, NAKAMURA, S, YAMAMURA, Y, KITOU, T, ITZKOWITZ, S. H, WERTHER, J. L, MIKI, K, TATEMATSU, M

“…Recent developments in mucin histochemistry and immunohistochemistry have made reliable determination of the gastric and intestinal phenotypes of gastric…”
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Heads or tails in a positive faecal occult blood test by Itzkowitz, Steven H

“…Itzkowitz examines faecal occult blood tests for the diagnosis of colorectal cancer in average-risk individuals aged over 50…”
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Liver metastasis and adhesion to the sinusoidal endothelium by human colon cancer cells is related to mucin carbohydrate chain length by Bresalier, Robert S., Byrd, James C., Brodt, Pnina, Ogata, Shunichiro, Itzkowitz, Steven H., Yunker, Christopher K.

“…Mucin production by human colon cancer cells correlates with liver metastasis in animal models, but it is not known which steps in metastasis depend on…”
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Use of model cell lines to study the biosynthesis and biological role of cancer-associated sialosyl-Tn antigen by OGATA, S, ANLI CHEN, ITZKOWITZ, S. H

“…Sialosyl-Tn (STn) is a mucin-associated carbohydrate antigen that is not expressed by most normal epithelial cells but becomes expressed in several types of…”
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Monoclonal antibody COL-1 reacts with restricted epitopes on carcinoembryonic antigen: an immunohistochemical study by Shi, ZR, Tacha, D, Itzkowitz, SH

“…We used a monoclonal antibody, MAb COL-1, which recognized a restricted epitope on the carcinoembryonic antigen (CEA) molecule, to stain a wide variety of…”
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