Search Results - "Itzel, Timo"
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TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice
Published in Cell death & disease (31-03-2020)“…Non-alcoholic fatty liver disease (NAFLD) shows an increasing prevalence and is associated with the development of liver fibrosis and cirrhosis as the major…”
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DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
Published in Cell metabolism (06-08-2013)“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (n =…”
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Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2016)“…Background & Aims Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Mouse models of NAFLD have…”
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Hepamine - A Liver Disease Microarray Database, Visualization Platform and Data-Mining Resource
Published in Scientific reports (16-03-2020)“…Numerous gene expression profiling data on liver diseases were generated and stored in public databases. Only few were used for additional analyses by the…”
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Prognostic Cancer Gene Expression Signatures: Current Status and Challenges
Published in Cells (Basel, Switzerland) (15-03-2021)“…Current staging systems of cancer are mainly based on the anatomical extent of disease. They need refinement by biological parameters to improve stratification…”
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RASSF1A independence and early galectin‐1 upregulation in PIK3CA‐induced hepatocarcinogenesis: new therapeutic venues
Published in Molecular oncology (01-03-2022)“…Aberrant activation of the phosphoinositide 3‐kinase (PI3K)/AKT/mTOR and Ras/mitogen‐activated protein kinase (MAPK) pathways is a hallmark of…”
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Nuclei Detection and Segmentation of Histopathological Images Using a Feature Pyramidal Network Variant of a Mask R-CNN
Published in Bioengineering (Basel) (01-10-2024)“…Cell nuclei interpretation is crucial in pathological diagnostics, especially in tumor specimens. A critical step in computational pathology is to detect and…”
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BMP-9 Modulates the Hepatic Responses to LPS
Published in Cells (Basel, Switzerland) (04-03-2020)“…It was previously shown that Bone Morphogenetic Protein (BMP)-9 is constitutively produced and secreted by hepatic stellate cells (HSC). Upon acute liver…”
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Prognostic Significance and Functional Relevance of Olfactomedin 4 in Early-Stage Hepatocellular Carcinoma
Published in Clinical and translational gastroenterology (01-01-2020)“…Hepatocellular carcinoma (HCC) is a leading cancer-related cause of death. Unfortunately, recurrence is common even after curative treatment of early-stage…”
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10
Deep view on HCC gene signatures and their comparison with other cancers
Published in Journal of hepatology (01-07-2022)Get full text
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SAT-402-Hepamine 2.0: Visualization and data-mining resource for liver disease
Published in Journal of hepatology (01-04-2019)Get full text
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Deep View of HCC Gene Expression Signatures and Their Comparison with Other Cancers
Published in Cancers (01-09-2022)“…Background: Gene expression signatures correlate genetic alterations with specific clinical features, providing the potential for clinical usage. A plethora of…”
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Letter to the editor: vaccination against upper respiratory infections is a matter of survival in alcoholic liver disease
Published in Gut (01-01-2023)Get more information
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14
Impact of concomitant cardiovascular medications on overall survival in patients with liver cirrhosis
Published in Scandinavian journal of gastroenterology (02-12-2023)“…OBJECTIVES OF THE ARTICLELiver cirrhosis is the end-stage liver disease associated with poor prognosis and cardiovascular comorbidity could significantly…”
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THU-559 - Evaluation of Google search trends for liver diseases in Europe
Published in Journal of hepatology (01-06-2023)Get full text
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Evaluation of Google search trends for liver diseases in Europe
Published in Journal of hepatology (01-06-2023)Get full text
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Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer
Published in The Journal of clinical investigation (01-05-2020)“…Hepatocellular carcinoma (HCC) is clearly age-related and represents one of the deadliest cancer types worldwide. As a result of globally increasing risk…”
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TGF-β2 silencing to target biliary-derived liver diseases
Published in Gut (01-09-2020)“…TGF-β2 (TGF-β, transforming growth factor beta), the less-investigated sibling of TGF-β1, is deregulated in rodent and human liver diseases. Former data from…”
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Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis
Published in Bioinformatics (Oxford, England) (15-01-2015)“…Co-regulated genes are not identified in traditional microarray analyses, but may theoretically be closely functionally linked [guilt-by-association (GBA),…”
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Digital Gastroenterology
Published in Journal of gastrointestinal and liver diseases : JGLD (12-12-2020)Get full text
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