Search Results - "Itri, Vincenza"

Differential V2-directed antibody responses in non-human primates infected with SHIVs or immunized with diverse HIV vaccines by Weiss, Svenja, Itri, Vincenza, Pan, Ruimin, Jiang, Xunqing, Luo, Christina C., Morris, Lynn, Malherbe, Delphine C., Barnette, Philip, Alexander, Jeff, Kong, Xiang-Peng, Haigwood, Nancy L., Hessell, Ann J., Duerr, Ralf, Zolla-Pazner, Susan

“…V2p and V2i antibodies (Abs) that are specific for epitopes in the V1V2 region of the HIV gp120 envelope (Env) do not effectively neutralize HIV but mediate…”
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Detection of Antibody Responses Against SARS-CoV-2 in Plasma and Saliva From Vaccinated and Infected Individuals by Klingler, Jéromine, Lambert, Gregory S, Itri, Vincenza, Liu, Sean, Bandres, Juan C, Enyindah-Asonye, Gospel, Liu, Xiaomei, Simon, Viviana, Gleason, Charles R, Kleiner, Giulio, Chiu, Hsin-Ping, Hung, Chuan-Tien, Kowdle, Shreyas, Amanat, Fatima, Lee, Benhur, Zolla-Pazner, Susan, Upadhyay, Chitra, Hioe, Catarina E

“…Antibodies (Abs) are essential for the host immune response against SARS-CoV-2, and all the vaccines developed so far have been designed to induce Abs…”
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Modulation of Antibody Responses to the V1V2 and V3 Regions of HIV-1 Envelope by Immune Complex Vaccines by Hioe, Catarina E, Kumar, Rajnish, Upadhyay, Chitra, Jan, Muzafar, Fox, Alisa, Itri, Vincenza, Peachman, Kristina K, Rao, Mangala, Liu, Lily, Lo, Nathan C, Tuen, Michael, Jiang, Xunqing, Kong, Xiang-Peng, Zolla-Pazner, Susan

“…Prophylactic HIV vaccines must elicit antibodies (Abs) against the virus envelope glycoproteins (Env) to effectively prevent HIV infection. We investigated a…”
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A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein by Kelker, Hanna C, Itri, Vincenza R, Valentine, Fred T

“…Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that…”
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Human Immunodeficiency Virus (HIV) Reverse Transcriptase Activity Correlates with HIV RNA Load: Implications for Resource-Limited Settings by SIVAPALASINGAM, Sumathi, ESSAJEE, Shaffiq, NYAMBI, Phillipe N, ITRI, Vincenza, HANNA, Bruce, HOLZMAN, Robert, VALENTINE, Fred

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of Immunoglobulin M and A Antibodies in the Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 by Klingler, Jéromine, Weiss, Svenja, Itri, Vincenza, Liu, Xiaomei, Oguntuyo, Kasopefoluwa Y, Stevens, Christian, Ikegame, Satoshi, Hung, Chuan-Tien, Enyindah-Asonye, Gospel, Amanat, Fatima, Baine, Ian, Arinsburg, Suzanne, Bandres, Juan C, Kojic, Erna Milunka, Stoever, Jonathan, Jurczyszak, Denise, Bermudez-Gonzalez, Maria, Nádas, Arthur, Liu, Sean, Lee, Benhur, Zolla-Pazner, Susan, Hioe, Catarina E

“…Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people globally. Virus infection requires the…”
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Plasticity and Epitope Exposure of the HIV-1 Envelope Trimer by Powell, Rebecca L R, Totrov, Maxim, Itri, Vincenza, Liu, Xiaomei, Fox, Alisa, Zolla-Pazner, Susan

“…We recently showed that mutations in the HIV-1 envelope (Env) destabilize the V3 loop, rendering neutralization-resistant viruses sensitive to V3-directed…”
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HIV-1 envelope glycan composition influences virus-host interaction by Hioe, Catarina E, Jan, Muzafar, Feyznezhad, Roya, Itri, Vincenza, Liu, Xiaomei, Upadhyay, Chitra

“…Abstract HIV-1 envelope (Env) is densely shrouded with oligomannose- and complex-type glycans. These glycans interact with lectins, a family of…”
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Modulation of epitope-specific antibody response by HIV Env immune-complex vaccines by Kumar, Rajnish, Tuen, Michael, Jiang, Xunqing, Itri, Vincenza, Pazner, Susan Zolla, Kong, Xiang-Peng, Hioe, Catarina

“…Abstract HIV-1 envelope (Env) antigen is an important target for both neutralizing and non-neutralizing antibodies (Ab) against the virus. In the RV144 vaccine…”
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Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses by Hessell, Ann J., Powell, Rebecca, Jiang, Xunqing, Luo, Christina, Weiss, Svenja, Dussupt, Vincent, Itri, Vincenza, Fox, Alisa, Shapiro, Mariya B., Pandey, Shilpi, Cheever, Tracy, Fuller, Deborah H., Park, Byung, Krebs, Shelly J., Totrov, Maxim, Haigwood, Nancy L., Kong, Xiang-Peng, Zolla-Pazner, Susan

“…The V1V2 region of the HIV-1 envelope is the target of several broadly neutralizing antibodies (bNAbs). Antibodies to V1V2 elicited in the RV144 clinical trial…”
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An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques by Powell, Rebecca L., Weiss, Svenja, Fox, Alisa, Liu, Xiaomei, Itri, Vincenza, Jiang, Xunqing, Luo, Christina C., Spencer, David A., Pandey, Shilpi, Cheever, Tracy, Fuller, Deborah H., Totrov, Maxim, Hessell, Ann J., Haigwood, Nancy L., Kong, Xiang-Peng, Zolla-Pazner, Susan

“…The only HIV vaccine trial for which protective efficacy was detected correlated this efficacy with V2-specific Abs that were effectively nonneutralizing. This…”
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Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques by Devasundaram, Santhi, Rosati, Margherita, Valentin, Antonio, Weiss, Svenja, Itri, Vincenza, Trinh, Hung V, Bear, Jenifer, Chowdhury, Bhabadeb, LaBranche, Celia C, Montefiori, David, Ferrari, Guido, Rao, Mangala, Kong, Xiang-Peng, Zolla-Pazner, Susan, Pavlakis, George N, Felber, Barbara K

“…The RV144 vaccine trial revealed a correlation between reduced risk of HIV infection and the level of nonneutralizing-antibody (Ab) responses targeting…”
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An HIV Vaccine Targeting the V2 Region of the HIV Envelope Induces a Highly Durable Polyfunctional Fc-Mediated Antibody Response in Rhesus Macaques by Powell, Rebecca L, Weiss, Svenja, Fox, Alisa, Liu, Xiaomei, Itri, Vincenza, Jiang, Xunqing, Luo, Christina C, Spencer, David A, Pandey, Shilpi, Cheever, Tracy, Fuller, Deborah H, Totrov, Maxim, Hessell, Ann J, Haigwood, Nancy L, Kong, Xiang-Peng, Zolla-Pazner, Susan

“…The HIV vaccine field now recognizes the potential importance of generating polyfunctional antibodies (Abs). The only clinical HIV vaccine trial to date to…”
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Differential induction of antibodies against immunogenic V1V2 and V3 regions of HIV-1 envelope by immune complex vaccines by Hioe, Catarina E., Kumar, Rajnish, Upadhyay, Chitra, Fox, Alicia, Itri, Vincenza, Peachman, Kristina, Rao, Mangala, Jiang, Xungqing, Kong, Xiangpeng, Zolla-Pazner, Susan

“…Abstract Antibodies (Abs) are critical elements of immune defense against HIV-1. Abs induced during infection or after immunization with HIV-1 envelope…”
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Primary Human Neutrophils Exhibit a Unique HIV-Directed Antibody-Dependent Phagocytosis Profile by Powell, Rebecca L.R., Fox, Alisa, Itri, Vincenza, Zolla-Pazner, Susan

“…The only clinical HIV vaccine trial to demonstrate efficacy, RV144, correlated protection with the antibodies (Abs) mediating function via the “constant”…”
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Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination by Balasubramanian, Preetha, Kumar, Rajnish, Williams, Constance, Itri, Vincenza, Wang, Shixia, Lu, Shan, Hessell, Ann J, Haigwood, Nancy L, Sinangil, Faruk, Higgins, Keith W, Liu, Lily, Li ,, Liuzhe, Nyambi, Phillipe, Gorny, Miroslaw K, Totrov, Maxim, Nadas, Arthur, Kong, Xiang-Peng, Zolla-Pazner, Susan, Hioe, Catarina E

“…Highlights • Abs with distinct V3-binding modes (cradle and ladle) are made during HIV infection. • In contrast, HIV envelope vaccines induce either the…”
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Eight prion strains have PrP(Sc) molecules with different conformations by Safar, J, Wille, H, Itri, V, Groth, D, Serban, H, Torchia, M, Cohen, F E, Prusiner, S B

“…Variations in prions, which cause different incubation times and deposition patterns of the prion protein isoform called PrP(Sc), are often referred to as…”
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Eight prion strains have PrPSc molecules with different conformations by Safar, Jiri, Wille, Holger, Itri, Vincenza, Groth, Darlene, Serban, Hana, Torchia, Marilyn, Cohen, Fred E., Prusiner, Stanley B.

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Phagocytosis of a Model Human Immunodeficiency Virus Target by Human Breast Milk Leukocytes Is Predominantly Granulocyte-Driven When Elicited by Specific Antibody by Powell, Rebecca L R, Fox, Alisa, Liu, Xiaomei, Itri, Vincenza

“…Studies demonstrate a protective effect of antibodies (Abs) in breast milk (BM) against mother-to-child transmission (MTCT) of human immunodeficiency virus…”
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P-C16 Differential Induction of Anti-V3 Crown Antibodies with Cradle and Ladle-Binding Modes in Response to HIV-1 Envelope Vaccination by Kumar, Rajnish, Williams, Constance, Itri, Vincenza, Wang, Shixia, Lu, Shan, Hessell, Ann, Higgins, Keith, Liu, Lily, Haigwood, Nancy, Sinangil, Faruk, Gorny, Miroslaw, Totrov, Max, Kong, Xiang, Nadas, Arthur, Zolla-Pazner, Susan, Hioe, Catarina, Balasubramanian, Preetha

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