Search Results - "Itri, Loretta"

TROPHY-U-01: A Phase II Open-Label Study of Sacituzumab Govitecan in Patients With Metastatic Urothelial Carcinoma Progressing After Platinum-Based Chemotherapy and Checkpoint Inhibitors by Tagawa, Scott T, Balar, Arjun V, Petrylak, Daniel P, Kalebasty, Arash Rezazadeh, Loriot, Yohann, Fléchon, Aude, Jain, Rohit K, Agarwal, Neeraj, Bupathi, Manojkumar, Barthelemy, Philippe, Beuzeboc, Philippe, Palmbos, Phillip, Kyriakopoulos, Christos E, Pouessel, Damien, Sternberg, Cora N, Hong, Quan, Goswami, Trishna, Itri, Loretta M, Grivas, Petros

“…Patients with metastatic urothelial carcinoma (mUC) who progress on platinum-based combination chemotherapy (PLT) and checkpoint inhibitors (CPIs) have limited…”
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Safety analyses from the phase 3 ASCENT trial of sacituzumab govitecan in metastatic triple-negative breast cancer by Rugo, Hope S., Tolaney, Sara M., Loirat, Delphine, Punie, Kevin, Bardia, Aditya, Hurvitz, Sara A., O’Shaughnessy, Joyce, Cortés, Javier, Diéras, Véronique, Carey, Lisa A., Gianni, Luca, Piccart, Martine J., Loibl, Sibylle, Goldenberg, David M., Hong, Quan, Olivo, Martin, Itri, Loretta M., Kalinsky, Kevin

“…Sacituzumab govitecan (SG) is an anti-Trop-2 antibody-drug conjugate with an SN-38 payload. In the ASCENT study, patients with metastatic triple-negative…”
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5-Year Survival in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia in a Randomized, Phase III Trial of Fludarabine Plus Cyclophosphamide With or Without Oblimersen by O'BRIEN, Susan, MOORE, Joseph O, RAI, Kanti R, BOYD, Thomas E, LARRATT, Loree M, SKOTNICKI, Aleksander B, KOZINER, Benjamin, CHANAN-KHAN, Asher A, SEYMOUR, John F, GRIBBEN, John, ITRI, Loretta M

“…A randomized trial of oblimersen plus fludarabine/cyclophosphamide (OBL-FC; n = 120) versus FC (n = 121) was conducted in patients with relapsed/refractory…”
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The Efficacy and Safety of the Fentanyl Iontophoretic Transdermal System (IONSYS®) in the Geriatric Population: Results of a Meta-Analysis of Phase III and IIIb Trials by Viscusi, Eugene R., Ding, Li, Itri, Loretta M.

“…Background and Objectives Acute postoperative pain management in the geriatric patient can be challenging, including their response to medications. The purpose…”
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LDH correlation with survival in advanced melanoma from two large, randomised trials (Oblimersen GM301 and EORTC 18951) by Agarwala, Sanjiv S, Keilholz, Ulrich, Gilles, Erard, Bedikian, Agop Y, Wu, Jane, Kay, Richard, Stein, Cy A, Itri, Loretta M, Suciu, Stefan, Eggermont, Alexander M.M

“…Abstract Purpose In a randomised study (GM301; dacarbazine with/without oblimersen), patients with advanced melanoma were stratified based on performance…”
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Author Correction: Safety analyses from the phase 3 ASCENT trial of sacituzumab govitecan in metastatic triple-negative breast cancer by Rugo, Hope S., Tolaney, Sara M., Loirat, Delphine, Punie, Kevin, Bardia, Aditya, Hurvitz, Sara A., O’Shaughnessy, Joyce, Cortés, Javier, Diéras, Véronique, Carey, Lisa A., Gianni, Luca, Piccart, Martine J., Loibl, Sibylle, Goldenberg, David M., Hong, Quan, Olivo, Martin, Itri, Loretta M., Kalinsky, Kevin

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Impact of Cancer‐Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition by Curt, Gregory A., Breitbart, William, Cella, David, Groopman, Jerome E., Horning, Sandra J., Itri, Loretta M., Johnson, David H., Miaskowski, Christine, Scherr, Susan L., Portenoy, Russell K., Vogelzang, Nicholas J.

“…Purpose. This survey was designed to confirm the prevalence and duration of fatigue in the cancer population and to assess its physical, mental, social, and…”
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Cancer‐Related Fatigue: Guidelines for Evaluation and Management by Portenoy, Russell K., Itri, Loretta M.

“…Fatigue is a highly prevalent condition among cancer patients. Although most cancer patients report that fatigue is a major obstacle to maintaining normal…”
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Chemotherapy-Induced Anemia in Adults: Incidence and Treatment by Groopman, Jerome E., Itri, Loretta M.

“…Anemia is a common complication of myelosuppressive chemotherapy that results in a decreased functional capacity and quality of life (QOL) for cancer patients…”
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Erythropoietin therapy for acute stroke is both safe and beneficial by Ehrenreich, Hannelore, Hasselblatt, Martin, Dembowski, Christoph, Cepek, Lukas, Lewczuk, Piotr, Stiefel, Michael, Rustenbeck, Hans-Heino, Breiter, Norbert, Jacob, Sonja, Knerlich, Friederike, Bohn, Matthias, Poser, Wolfgang, Rüther, Eckart, Kochen, Michael, Gefeller, Olaf, Gleiter, Christoph, Wessel, Thomas C, De Ryck, Marc, Itri, Loretta, Prange, Hilmar, Cerami, Anthony, Brines, Michael, Sirén, Anna-Leena

“…Erythropoietin (EPO) and its receptor play a major role in embryonic brain, are weakly expressed in normal postnatal/adult brain and up-regulated upon…”
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Fentanyl Iontophoretic Transdermal System (IONSYS®) can be Safely used in the Hospital Environment with X-Rays, Computerized Tomography and Radiofrequency Identification Devices by Lemke, John, Sardariani, Edmond, Phipps, Joseph Bradley, Patel, Niki, Itri, Loretta M., Caravelli, James, Viscusi, Eugene R.

“…Introduction Fentanyl iontophoretic transdermal system (fentanyl ITS, IONSYS ® ) is a patient-controlled analgesia system used for the management of acute…”
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High Body Mass Index and Use of Fentanyl Iontophoretic Transdermal System in Postoperative Pain Management: Results of a Pooled Analysis of Six Phase 3/3B Trials by Viscusi, Eugene R., Ding, Li, Phipps, J. Bradley, Itri, Loretta M., Schauer, Philip R.

“…Introduction Postoperative pain management can be challenging in patients with a high body mass index (BMI) especially as a result of poor venous access and…”
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Erythropoietin Crosses the Blood-Brain Barrier to Protect against Experimental Brain Injury by Brines, Michael L., Ghezzi, Pietro, Keenan, Sonja, Agnello, Davide, De Lanerolle, Nihal C., Cerami, Carla, Itri, Loretta M., Cerami, Anthony

“…Erythropoietin (EPO), recognized for its central role in erythropoiesis, also mediates neuroprotection when the recombinant form (r-Hu-EPO) is directly…”
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Use of Fentanyl Iontophoretic Transdermal System (ITS) (IONSYS®) in the Management of Patients with Acute Postoperative Pain: A Case Series by Poplawski, Steven, Johnson, Matthew, Philips, Philip, Eberhart, Leopold H. J., Koch, Tilo, Itri, Loretta M.

“…Fentanyl iontophoretic transdermal system (ITS) [IONSYS ® , The Medicines Company, Parsippany, NJ, USA] is a needle-free, patient-controlled, postoperative…”
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Neuroprotective properties of epoetin alfa by Cerami, Anthony, Brines, Michael, Ghezzi, Pietro, Cerami, Carla, Itri, Loretta M.

“…Erythropoietin and its receptor function as primary mediators of the normal physiological response to hypoxia. Erythropoietin is recognized for its central…”
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Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid) by Warrell, Raymond P, Frankel, Stanley R, Miller, Wilson H, Scheinberg, David A, Itri, Loretta M, Hittelman, Walter N, Vyas, Rohini, Andreeff, Michael, Tafuri, Agostino, Jakubowski, Ann, Gabrilove, Janice, Gordon, Michael S, Dmitrovsky, Ethan

“…ACUTE promyelocytic leukemia makes up approximately 15 percent of the adult acute nonlymphoblastic leukemias. 1 The disease is associated with a specific…”
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The use of epoetin alfa in chemotherapy patients: A consistent profile of efficacy and safety by Itri, Loretta M.

“…Epoetin alfa has been in use for over a decade to increase hemoglobin in patients with cancer who develop chemotherapy-associated anemia. Early…”
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Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck by Hong, Waun KI, Lippman, Scott M, Itri, Loretta M, Karp, Daniel D, Lee, Jin S, Byers, Robert M, Schantz, Stimson P, Kramer, Alan M, Lotan, Reuben, Peters, Lester J, Dimery, Isaiah W, Brown, Barry W, Goepfert, Helmuth

“…Cancers of the lung, esophagus, and head and neck are expected to account for nearly one third of the 500,000 deaths due to cancer that have been predicted to…”
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Managing cancer‐related anaemia with epoetin alfa by ITRI, Loretta M

“…Anaemia occurs in a significant number of patients with cancer, and is associated with symptoms of fatigue, dizziness, headache and decreased health‐related…”
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Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer by Bardia, Aditya, Hurvitz, Sara A, Tolaney, Sara M, Loirat, Delphine, Punie, Kevin, Oliveira, Mafalda, Brufsky, Adam, Sardesai, Sagar D, Kalinsky, Kevin, Zelnak, Amelia B, Weaver, Robert, Traina, Tiffany, Dalenc, Florence, Aftimos, Philippe, Lynce, Filipa, Diab, Sami, Cortés, Javier, O’Shaughnessy, Joyce, Diéras, Véronique, Ferrario, Cristiano, Schmid, Peter, Carey, Lisa A, Gianni, Luca, Piccart, Martine J, Loibl, Sibylle, Goldenberg, David M, Hong, Quan, Olivo, Martin S, Itri, Loretta M, Rugo, Hope S

“…Patients with metastatic triple-negative breast cancer were treated with standard chemotherapy or the anti–Trop-2 antibody–drug conjugate sacituzumab…”
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