Search Results - "Itoh, Fumiaki"

Extraction of optimal synthesis conditions from scientific literature using a knowledge graph by Kobayashi, Shigeru, Kuwashiro, Norikazu, Itoh, Fumiaki, Sakurai, Dai, Hitosugi, Taro

“…Autonomous experiments for material synthesis have been developing with increasing speed. With the expanding search space for accessible materials, the…”
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Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level by Katsuno, Kenji, Fujimori, Yoshikazu, Takemura, Yukiko, Hiratochi, Masahiro, Itoh, Fumiaki, Komatsu, Yoshimitsu, Fujikura, Hideki, Isaji, Masayuki

“…The low-affinity sodium glucose cotransporter (SGLT2), which is expressed specifically in the kidney, plays a major role in renal glucose reabsorption in the…”
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KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models by Shibazaki, Toshihide, Tomae, Masaki, Ishikawa-Takemura, Yukiko, Fushimi, Nobuhiko, Itoh, Fumiaki, Yamada, Mitsuhiko, Isaji, Masayuki

“…The high-affinity sodium glucose cotransporter (SGLT1) plays a critical role in glucose absorption from the gastrointestinal tract. We have developed…”
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Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout by Tatani, Kazuya, Hiratochi, Masahiro, Kikuchi, Norihiko, Kuramochi, Yu, Watanabe, Shinjiro, Yamauchi, Yuji, Itoh, Fumiaki, Isaji, Masayuki, Shuto, Satoshi

“…To test the hypothesis that inhibitors of human concentrative nucleoside transporter 2 (hCNT2) suppress increases in serum urate levels derived from dietary…”
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Length of lags in responses of milk yield and somatic cell score on test day to heat stress in Holsteins by Hagiya, Koichi, Bamba, Ikumi, Osawa, Takefumi, Atagi, Yamato, Takusari, Naozumi, Itoh, Fumiaki, Yamazaki, Takeshi

“…We used daily records from provincial Japanese weather stations and monthly test‐day records of milk production to investigate the length of the lags in the…”
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Bovine milk lactoferrin induces synthesis of the angiogenic factors VEGF and FGF2 in osteoblasts via the p44/p42 MAP kinase pathway by Nakajima, Kei-ichi, Kanno, Yosuke, Nakamura, Masato, Gao, Xiao-Dong, Kawamura, Asami, Itoh, Fumiaki, Ishisaki, Akira

“…Lactoferrin (LF) belongs to the transferrin family and is present in several physiological fluids, including milk and colostrum. LF has recently been…”
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Further Evidence for the Role of Glucose as a Metabolic Regulator of Hypothalamic Gonadotropin-Releasing Hormone Pulse Generator Activity in Goats by Ohkura, Satoshi, Ichimaru, Toru, Itoh, Fumiaki, Matsuyama, Shuichi, Okamura, Hiroaki

“…The present study examined the relative importance of blood glucose vs. free fatty acids as a metabolic signal regulating GnRH release as measured…”
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Effects of ghrelin injection on plasma concentrations of glucose, pancreatic hormones and cortisol in Holstein dairy cattle by Itoh, Fumiaki, Komatsu, Tokushi, Kushibiki, Shiro, Hodate, Koichi

“…Ghrelin affects not only growth hormone secretion but also nutrient utilization and metabolic hormone secretion in humans and experimental animals. The effects…”
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Effects of amino acids infused into the vein on ghrelin-induced GH, insulin and glucagon secretion in lactating cows by FUKUMORI, Rika, YOKOTANI, Akinori, SUGINO, Toshihisa, ITOH, Fumiaki, KUSHIBIKI, Shiro, SHINGU, Hiroyuki, MORIYA, Naoko, HASEGAWA, Yoshihisa, KOJIMA, Masayasu, KANGAWA, Kenji, OBITSU, Taketo, TANIGUCHI, Kohzo

“…ABSTRACT To investigate the effects of amino acids on ghrelin‐induced growth hormone (GH), insulin and glucagon secretion in lactating dairy cattle, six…”
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Influence of orally administered bovine lactoferrin on lipid metabolism in lipopolysaccharide-injected preruminant calves by Kushibiki, S.(National Inst. of Livestock and Grassland Science, Tsukuba, Ibaraki (Japan)), Shingu, H, Komatsu, T, Itoh, F, Moriya, N, Touno, E, Oshibe, A, Hodate, K

“…ABSTRACT The aim of this study was to investigate the influence of oral lactoferrin (LF) administration on lipid metabolism changes in calves given…”
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Changes in the gene expression of adiponectin and glucose transporter 12 (GLUT12) in lactating and non-lactating cows by Komatsu, T.(National Inst. of Livestock and Grassland Science, Tsukuba, Ibaraki (Japan)), Itoh, F, Sakumoto, R, Hodate, K, Obara, Y, Kushibiki, S

“…Glucose delivery and uptake by the mammary gland is a rate-limiting step in milk synthesis. Insulin resistance is believed to increase throughout the body…”
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Effect of bovine lactoferrin feeding on lipopolysaccharide-induced metabolic and hormonal disturbances in preruminant calves by Kushibiki, S.(National Inst. of Livestock and Grassland Science, Tsukuba, Ibaraki (Japan)), Shingu, H, Kawasaki, R, Komatsu, T, Itoh, F, Watanabe, A, Touno, E, Oshibe, A, Katoh, K, Obara, Y, Hodate, K

“…One of the biological functions of bovine lactoferrin (LF) is modulation of the host defense system, including cytokine production and immune response. The aim…”
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Rat model of the hypercalcaemia induced by parathyroid hormone-related protein: characteristics of three bisphosphonates by Komatsu, Yoshimitsu, Imai, Yohsuke, Itoh, Fumiaki, Kojima, Masami, Isaji, Masayuki, Shibata, Nobuo

“…In our preliminary experiment, we found that a constant infusion of a high dose of parathyroid hormone-related protein induced both hyperphosphataemia and…”
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Gene expression of resistin and TNF-α in adipose tissue of Japanese Black steers and Holstein steers by KOMATSU, Tokushi, ITOH, Fumiaki, HODATE, Koichi, HAZEGAWA, Shuhei, OBARA, Yoshiaki, KUSHIBIKI, Shiro

“…ABSTRACT The aim of the present study was to compare the expression of adipose tissue mRNA related to glucose metabolism between Japanese Black steers (n = 5)…”
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Effect of recombinant bovine tumor necrosis factor-α on hormone release in lactating cows by KUSHIBIKI, Shiro, SHINGU, Hiroyuki, KOMATSU, Tokushi, ITOH, Fumiaki, KASUYA, Etsuko, ASO, Hisashi, HODATE, Koichi

“…ABSTRACT Tumor necrosis factor (TNF)‐α is a powerful macrophage cytokine released during infection, circulating in the blood to produce diverse effects in the…”
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Evaluation of the high affinity IgE receptor alpha-IgG1 Fc fusion protein (FCER1A-Fc) as a topical ocular anti-allergic agent by Homma, Toshiki, Yokoyama, Kazumasa, Itoh, Fumiaki, Sakamoto, Takashi, Yamagishi, Mika, Ra, Chisei, Suzuki, Yasuhiko, Inada, Yoichi

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Effects of Heat Exposure on Adrenergic Modulation of Insulin and Glucagon Secretion in Sheep by ITOH, FUMIAKI, HODATE, KOICRN, KOYAMA, SHINICHIRO, ROSE, MICHAEL T, MATSUMOTO, MITSUTO, OZAWA, AKIHITO, OBARA, YOSHIAKI

“…The effects of heat exposure on the adrenergic modulation of pancreatic secretion were investigated. Five ewes fed at maintenance level (ME base) were housed…”
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Decreases of apolipoprotein B-100 and A-I concentrations and induction of haptoglobin and serum amyloid A in nonfed calves by Katoh, N. (National Inst. of Animal Health, Sapporo (Japan). Hokkaido Research Station), Oikawa, S, Oohashi, T, Takahashi, Y, Itoh, F

“…Reduced feed intake near parturition is suggested to be one of the major causal factors for the development of fatty liver incows, and nonfeeding has been used…”
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Bovine apolipoprotein E in plasma: Increase of ApoE concentration induced by fasting and distribution in lipoprotein fractions by Takahashi, Y. (National Inst. of Animal Health, Tsukuba, Ibaraki (Japan)), Sato, K, Itoh, F, Miyamoto, T, Oohashi, T, Katoh, N

“…Apolipoprotein E (apoE) is a protein constituent of lipoproteins, and acts as a receptor-binding ligand. Although the existence of bovine apoE in lipoprotein…”
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Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides by Hiratochi, Masahiro, Tatani, Kazuya, Shimizu, Kazuo, Kuramochi, Yu, Kikuchi, Norihiko, Kamada, Noboru, Itoh, Fumiaki, Isaji, Masayuki

“…We have developed concentrative nucleoside transporter 2 (CNT2) inhibitors as a novel pharmacological approach for improving hyperuricemia by inhibiting…”
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