Search Results - "Ito, Naoki"
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The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People-A Randomized, Double-Blind, Placebo-Controlled Trial
Published in Nutrients (25-06-2018)“…Skin is a major safeguard tissue in humans. Because biological barrier function is deteriorated by several kinds of stresses including exposure to ultra-violet…”
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Regulation of muscle hypertrophy: Involvement of the Akt-independent pathway and satellite cells in muscle hypertrophy
Published in Experimental cell research (15-12-2021)“…Skeletal muscles are composed of multinuclear cells called myofibers and have unique abilities, one of which is plasticity. In response to the mechanical load…”
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Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy
Published in Nature medicine (01-01-2013)“…Shin'ichi Takeda and colleagues show that loading of muscle results in nitric oxide creation and its conversion to peroxynitrite. The latter molecule then…”
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Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline
Published in Nature communications (26-03-2015)“…Acute seizures after a severe brain insult can often lead to epilepsy and cognitive impairment. Aberrant hippocampal neurogenesis follows the insult but the…”
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Ubiquitin-mediated mitochondrial regulation by MITOL/MARCHF5 at a glance
Published in Journal of biochemistry (Tokyo) (01-01-2023)“…Mitochondria are involved in various cellular processes, such as energy production, inflammatory responses and cell death. Mitochondrial dysfunction is…”
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Effects of Composite Supplement Containing Collagen Peptide and Ornithine on Skin Conditions and Plasma IGF-1 Levels-A Randomized, Double-Blind, Placebo-Controlled Trial
Published in Marine drugs (03-12-2018)“…Aging-associated changes of skin conditions are a major concern for maintaining quality of life. Therefore, the improvement of skin conditions by dietary…”
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Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration
Published in International journal of molecular sciences (31-03-2021)“…Skeletal muscle regeneration is a well-organized process that requires remodeling of the extracellular matrix (ECM). In this study, we revealed the protective…”
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Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process
Published in Journal of antibiotics (01-10-2019)“…The pandemic influenza 2009 (A(H1N1)pdm09) virus currently causes seasonal and annual epidemic outbreaks. The widespread use of anti-influenza drugs such as…”
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Pelvic organ prolapse and Japanese lifestyle: prevalence and risk factors in Japan
Published in International Urogynecology Journal (01-01-2022)“…Introduction and hypothesis Little is known about the prevalence of pelvic organ prolapse (POP). We aimed to evaluate the prevalence of POP and identify its…”
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Transcriptome analysis of gravitational effects on mouse skeletal muscles under microgravity and artificial 1 g onboard environment
Published in Scientific reports (28-04-2021)“…Spaceflight causes a decrease in skeletal muscle mass and strength. We set two murine experimental groups in orbit for 35 days aboard the International Space…”
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Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
Published in Cell reports (Cambridge) (26-07-2022)“…Sarcopenia and frailty are urgent socio-economic problems worldwide. Here we demonstrate a functional connection between the lateral hypothalamus (LH) and…”
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Direct reprogramming of fibroblasts into skeletal muscle progenitor cells by transcription factors enriched in undifferentiated subpopulation of satellite cells
Published in Scientific reports (14-08-2017)“…Satellite cells comprise a functionally heterogeneous population of stem cells in skeletal muscle. Separation of an undifferentiated subpopulation and…”
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Preventive effect of a Kampo medicine, kososan, on recurrent depression in a mouse model of repeated social defeat stress
Published in Gene (05-01-2022)“…•Stress-experienced mice recurred depression by re-exposure of single stress.•Kososan, but not milnacipran, prevented the recurrent depression in mice.•We…”
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Emotional Impairments and Neuroinflammation are Induced in Male Mice Invulnerable to Repeated Social Defeat Stress
Published in Neuroscience (01-09-2020)“…•Modified repeated social defeat stress (mRSDS) triggers negative cognitive bias and depression-like behaviors in BALB/c mice.•Mice susceptible and resilient…”
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Solvation Dynamics and Electric Field Relaxation in an Imidazolium-PF6 Ionic Liquid: from Room Temperature to the Glass Transition
Published in The journal of physical chemistry. B (10-05-2007)“…Time-resolved phosphorescence spectra and anisotropy of quinoxaline were measured in an ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate…”
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Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy
Published in PloS one (30-03-2011)“…Duchenne muscular dystrophy (DMD) is a lethal X-linked disorder caused by mutations in the dystrophin gene, which encodes a cytoskeletal protein, dystrophin…”
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ATP-Induced Increase in Intracellular Calcium Levels and Subsequent Activation of mTOR as Regulators of Skeletal Muscle Hypertrophy
Published in International journal of molecular sciences (18-09-2018)“…Intracellular signaling pathways, including the mammalian target of rapamycin (mTOR) and the mitogen-activated protein kinase (MAPK) pathway, are activated by…”
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Ferric derisomaltose for the treatment of iron deficiency anemia with postpartum hemorrhage: Results of a single‐arm, open‐label, phase 3 study in Japan
Published in The journal of obstetrics and gynaecology research (01-03-2023)“…Aim Single‐arm, open‐label, phase 3 study to evaluate the efficacy and safety of ferric derisomaltose (FDI) for iron deficiency anemia (IDA) in Japanese women…”
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C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
Published in Brain (London, England : 1878) (01-04-2017)“…A non-coding hexanucleotide repeat expansion in intron 1 of the C9orf72 gene is the most common cause of amyotrophic lateral sclerosis and frontotemporal…”
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Effects of Dietary Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized, Double-Blind, Placebo-Controlled, Two-Way Crossover Study
Published in Nutrients (28-02-2018)“…Severe fatigue can negatively affect quality of life, and oxidative stress may play a role in its mechanism. The aim of this study was to evaluate the effect…”
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