Search Results - "Ito, Kentaro"
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Epithelial-to-Mesenchymal Transition is a Cause of Both Intrinsic and Acquired Resistance to KRAS G12C Inhibitor in KRAS G12C-Mutant Non-Small Cell Lung Cancer
Published in Clinical cancer research (15-11-2020)“…is among the most commonly mutated oncogene in cancer including non-small cell lung cancer (NSCLC). In early clinical trials, inhibitors targeting G12C-mutant…”
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Real‐world data on NGS using the Oncomine DxTT for detecting genetic alterations in non‐small‐cell lung cancer: WJOG13019L
Published in Cancer science (01-01-2022)“…Considering the increasing number of identified driver oncogene alterations, additional genetic tests are required to determine the treatment for advanced…”
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Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction
Published in Journal of molecular and cellular cardiology (01-09-2013)“…Abstract Acute myocardial infarction (MI) causes sterile inflammation, which is characterized by recruitment and activation of innate and adaptive immune…”
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Solid-state surfactant templating for controlled synthesis of amorphous 2D oxide/oxyhydroxide nanosheets
Published in Nature communications (04-08-2024)“…As a member of 2D family, amorphous 2D nanosheets have received increasing attention due to their unique properties that are distinct from crystalline 2D…”
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Rules for Biologically Inspired Adaptive Network Design
Published in Science (American Association for the Advancement of Science) (22-01-2010)“…Transport networks are ubiquitous in both social and biological systems. Robust network performance involves a complex trade-off involving cost, transport…”
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Highly Sensitive Electrochemical Immunoassay Using Signal Amplification of the Coagulation Cascade
Published in Analytical chemistry (Washington) (13-09-2022)“…Here, we report a highly sensitive immunoassay for human immunoglobulin G (IgG) that uses signal amplification of the coagulation cascade…”
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Free‐Standing Molecularly Thin Amorphous Silica Nanosheets
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2023)“…Recent progress in 2D materials has initiated new fields of molecularly thin amorphous materials with mysterious properties and structures. However, designed…”
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A Synthetic Lethality-Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1
Published in Cancer research (Chicago, Ill.) (01-09-2013)“…The occurrence of inactivating mutations in SWI/SNF chromatin-remodeling genes in common cancers has attracted a great deal of interest. However, mechanistic…”
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Adventitial CXCL1/G-CSF Expression in Response to Acute Aortic Dissection Triggers Local Neutrophil Recruitment and Activation Leading to Aortic Rupture
Published in Circulation research (13-02-2015)“…RATIONALE:In-hospital outcomes are generally acceptable in patients with type B dissection; however, some patients present with undesirable complications, such…”
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Effect of Flavanol-Rich Cacao Extract on the Profile of Mood State in Healthy Middle-Aged Japanese Women: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
Published in Nutrients (01-09-2023)“…To investigate the effects of flavanol-rich cacao extract on healthy middle-aged women’s fatigue and mood conditions, we conducted a randomized, double-blind,…”
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Mechanics of peristaltic locomotion and role of anchoring
Published in Journal of the Royal Society interface (07-02-2012)“…Limbless crawling is a fundamental form of biological locomotion adopted by a wide variety of species, including the amoeba, earthworm and snake. An…”
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Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51
Published in Nature communications (11-06-2020)“…During homologous recombination, Rad51 forms a nucleoprotein filament on single-stranded DNA to promote DNA strand exchange. This filament binds to…”
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β-type TiNbSn Alloy Plates With Low Young Modulus Accelerates Osteosynthesis in Rabbit Tibiae
Published in Clinical orthopaedics and related research (01-09-2022)“…Ti6Al4V alloy, which is commonly used for biomedical applications, has a Young modulus (110 GPa) that is higher than that of human cortical bone (11 to 20…”
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Modulation of acoustic navigation behaviour by spatial learning in the echolocating bat Rhinolophus ferrumequinum nippon
Published in Scientific reports (01-07-2020)“…Using echolocation, bats receive acoustic information on their surroundings, which is assumed to help them sophisticatedly navigate complex environments. In…”
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Human Rad51 Protein Requires Higher Concentrations of Calcium Ions for D-Loop Formation than for Oligonucleotide Strand Exchange
Published in International journal of molecular sciences (01-04-2024)“…Human Rad51 protein (HsRad51)-promoted DNA strand exchange, a crucial step in homologous recombination, is regulated by proteins and calcium ions. Both the…”
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Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms
Published in Proceedings of the National Academy of Sciences - PNAS (02-06-2020)“…Homologous recombination (HR) is a universal mechanism operating in somatic and germ-line cells, where it contributes to the maintenance of genome stability…”
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Inter‐colony foraging area segregation quantified in small colonies of Adélie Penguins
Published in Ibis (London, England) (01-01-2021)“…Theoretical models on the movement of colonial animals predict that neighbouring colonies may segregate their foraging areas, and many seabird studies have…”
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Electric and Electrochemical Microfluidic Devices for Cell Analysis
Published in Frontiers in chemistry (04-06-2019)“…Microfluidic devices are widely used for cell analysis, including applications for single-cell analysis, healthcare, environmental monitoring, and…”
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Two three-strand intermediates are processed during Rad51-driven DNA strand exchange
Published in Nature structural & molecular biology (01-01-2018)“…During homologous recombination, Rad51 forms a nucleoprotein filament with single-stranded DNA (ssDNA) that undergoes strand exchange with homologous…”
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