Search Results - "Ito, Abel Bult"

Bidirectional Behavioral Selection in Mice: A Novel Pre-clinical Approach to Examining Compulsivity by Mitra, Swarup, Bult-Ito, Abel

“…Obsessive-compulsive disorder (OCD) and related disorders (OCRD) is one of the most prevalent neuropsychiatric disorders with no definitive etiology. The…”
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Allosterism of Nicotinic Acetylcholine Receptors: Therapeutic Potential for Neuroinflammation Underlying Brain Trauma and Degenerative Disorders by Mitra, Swarup, Khatri, Shailesh N, Maulik, Malabika, Bult-Ito, Abel, Schulte, Marvin

“…Inflammation is a key physiological phenomenon that can be pervasive when dysregulated. Persistent chronic inflammation precedes several pathophysiological…”
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Strain and sex based characterization of behavioral expressions in non-induced compulsive-like mice by Mitra, Swarup, Bastos, Cristiane P, Chesworth, Savanna, Frye, Cheryl, Bult-Ito, Abel

“…Abstract There is currently a lack of understanding how genetic background and sex differences attribute to the heterogeneity of obsessive-compulsive disorder…”
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Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models by Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E, Vayndorf, Elena M

“…Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the…”
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Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans by Maulik, Malabika, Mitra, Swarup, Basmayor, Ajiel Mae, Lu, Brianna, Taylor, Barbara E, Bult-Ito, Abel

“…The molecular basis of Parkinson's disease (PD) is currently unknown. There is increasing evidence that fat metabolism is at the crossroad of key molecular…”
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Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments by Maulik, Malabika, Mitra, Swarup, Sweeney, McKenzie, Lu, Brianna, Taylor, Barbara E., Bult-Ito, Abel

“…[Display omitted] •Alaskan blueberries ameliorate metal-induced neurotoxicity.•Diet interactions modulate rescue of behavioral deficits by Alaskan…”
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Postpartum Lactation-Mediated Behavioral Outcomes and Drug Responses in a Spontaneous Mouse Model of Obsessive–Compulsive Disorder by Mitra, Swarup, Mucha, McKenzie, Owen, Savanah, Bult-Ito, Abel

“…Using a spontaneous mouse model of obsessive–compulsive disorder (OCD), the current study evaluated the influence of postpartum lactation on the expression of…”
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Ovarian Sex Hormones Modulate Compulsive, Affective and Cognitive Functions in A Non-Induced Mouse Model of Obsessive-Compulsive Disorder by Mitra, Swarup, Bastos, Cristiane P, Bates, Katherine, Pereira, Grace S, Bult-Ito, Abel

“…There is currently a lack of understanding of how surgical menopause can influence obsessions, compulsions and associated affective and cognitive functions in…”
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Entrainment of the master circadian clock by scheduled feeding by Castillo, Marina R, Hochstetler, Kelly J, Tavernier, Jr, Ronald J, Greene, Dana M, Bult-Ito, Abel

“…The master circadian clock, located in the mammalian suprachiasmatic nuclei (SCN), generates and coordinates circadian rhythmicity, i.e., internal organization…”
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Attenuation of compulsive-like behavior by fluvoxamine in a non-induced mouse model of obsessive–compulsive disorder by Mitra, Swarup, Bult-Ito, Abel

“…The current study evaluated the role of strain and compulsive trait differences in response to fluvoxamine, a common obsessive–compulsive disorder (OCD) drug,…”
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Effect of Alaskan low bush cranberry on alpha‐synuclein overexpression in a transgenic model of C. elegans by Lu, Brianna, Maulik, Malabika, Bult‐Ito, Abel

“…Parkinson's Disease is the second most prevalent neurodegenerative disorder affecting more than 10 million worldwide (Tanner and Goldman 1996). The disease is…”
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Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive-compulsive disorder by Winter, Christine, Greene, Dana M., Mavrogiorgou, Paraskevi, Schaper, Helge, Sohr, Reinhard, Bult-Ito, Abel, Juckel, Georg

“…There is ample evidence that obsessive-compulsive disorder (OCD) is based on reduced serotonergic function. Replicated bidirectional selection for…”
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Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans by Maulik, Malabika, Mitra, Swarup, Hunter, Skyler, Hunstiger, Moriah, Oliver, S. Ryan, Bult-Ito, Abel, Taylor, Barbara E.

“…Misfolding and accumulation of cellular protein aggregates are pathological hallmarks of aging and neurodegeneration. One such protein is α-synuclein, which…”
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Alaskan berry treatments maintain C. elegans motility and sarcomere integrity with age by Touray, Farimang, Maulik, Malabika, Scerbak, Courtney, Vayndorf, Elena, Ito, Abel Bult, Taylor, Barbara

“…Abstract only Maintaining health with age is a major health concern due to loss of muscle mass, locomotion and increased likelihood of developing…”
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Trait specific modulatory effects of caffeine exposure on compulsive-like behaviors in a spontaneous mouse model of obsessive-compulsive disorder by Mitra, Swarup, Santana Miranda, Vanessa, McMillan, Casey, Dykes, Daniel, Mucha, McKenzie, Marth, Tandi E., Poe, Brooks, Basu, Debarati Ghosh, Bult-Ito, Abel

“…Obsessive-compulsive disorder (OCD) is a psychiatric disorder characterized by recurring intrusive thoughts and repetitive compulsive behaviors, ultimately…”
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Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice by Mitra, Swarup, Mucha, Mckenzie, Khatri, Shailesh N, Glenon, Richard, Schulte, Marvin K, Bult-Ito, Abel

“…Nicotinic α4β2 receptors are the most abundant subtypes of nicotinic acetylcholine receptors (nAChRs) expressed in brain regions implicated in obsessive…”
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Phase Resetting Light Pulses Induce Per1 and Persistent Spike Activity in a Subpopulation of Biological Clock Neurons by Kuhlman, Sandra J, Silver, Rae, Le Sauter, Joseph, Bult-Ito, Abel, McMahon, Douglas G

“…The endogenous circadian clock of the mammalian suprachiasmatic nucleus (SCN) can be reset by light to synchronize the biological clock of the brain with the…”
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Diet and mental health in the Arctic: is diet an important risk factor for mental health in circumpolar peoples? - a review by McGrath-Hanna, Nancy K., Greene, Dana M., Tavernier, Ronald J., Bult-Ito, Abel

“…Background. The people living in Arctic and Subarctic environments have adapted to cold temperatures, short growing seasons, and low precipitation, but their…”
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Distribution of NMDA receptor subunit NR1 in Arctic ground squirrel central nervous system by Zhao, Huiwen W., Christian, Sherri L., Castillo, Marina R., Bult-Ito, Abel, Drew, Kelly L.

“…Hibernation is a natural model of neuroprotection and adult synaptic plasticity. NMDA receptors (NMDAR), which play key roles in excitotoxicity and synaptic…”
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Phase shifts and Per gene expression in mouse suprachiasmatic nucleus by Yan, Lily, Hochstetler, Kelly J., Silver, Rae, Bult-Ito, Abel

“…In mammals, circadian rhythms controlled by the suprachiasmatic nuclei are entrained by photic stimuli. To investigate the molecular mechanism of photic…”
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