Search Results - "Issoglio, Federico M"

3-Nitrotyrosine and related derivatives in proteins: precursors, radical intermediates and impact in function by Campolo, Nicolás, Issoglio, Federico M, Estrin, Darío A, Bartesaghi, Silvina, Radi, Rafael

“…Oxidative post-translational modification of proteins by molecular oxygen (O2)- and nitric oxide (•NO)-derived reactive species is a usual process that occurs…”
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Metabolic and Structural Insights into Hydrogen Sulfide Mis-Regulation in Enterococcus faecalis by Walsh, Brenna J C, Costa, Sofia Soares, Edmonds, Katherine A, Trinidad, Jonathan C, Issoglio, Federico M, Brito, José A, Giedroc, David P

“…Hydrogen sulfide (H S) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and…”
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Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation by Campolo, Nicolás, Mastrogiovanni, Mauricio, Mariotti, Michele, Issoglio, Federico M., Estrin, Darío, Hägglund, Per, Grune, Tilman, Davies, Michael J., Bartesaghi, Silvina, Radi, Rafael

“…Glutamine synthetase (GS), which catalyzes the ATP-dependent synthesis of L-glutamine from L-glutamate and ammonia, is a ubiquitous and conserved enzyme that…”
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Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1 by Muñoz Sosa, Christian J., Issoglio, Federico M., Carrizo, María E.

“…Tripartite motif (TRIM)7 is an E3 ubiquitin ligase that was first identified through its interaction with glycogenin-1 (GN1), the autoglucosyltransferase that…”
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Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate by Freeman, Samuel L., Skafar, Vera, Kwon, Hanna, Fielding, Alistair J., Moody, Peter C.E., Martínez, Alejandra, Issoglio, Federico M., Inchausti, Lucas, Smircich, Pablo, Zeida, Ari, Piacenza, Lucía, Radi, Rafael, Raven, Emma L.

“…The protozoan parasite Trypanosoma cruzi is the causative agent of American trypanosomiasis, otherwise known as Chagas disease. To survive in the host, the…”
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Production, homology modeling and mutagenesis studies on GlcH glucose transporter from Prochlorococcus sp. strain SS120 by Moreno-Cabezuelo, José Ángel, Del Carmen Muñoz-Marín, María, López-Lozano, Antonio, Athayde, Diogo, Simón-García, Ana, Díez, Jesús, Archer, Margarida, Issoglio, Federico M, García-Fernández, José Manuel

“…The marine cyanobacterium Prochlorococcus is one of the main primary producers on Earth, which can take up glucose by using the high affinity, multiphasic…”
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Exploring the Catalytic Mechanism of Human Glutamine Synthetase by Computer Simulations by Issoglio, Federico M, Campolo, Nicolas, Zeida, Ari, Grune, Tilman, Radi, Rafael, Estrin, Dario A, Bartesaghi, Silvina

“…Glutamine synthetase is an important enzyme that catalyzes the ATP-dependent formation of glutamine from glutamate and ammonia. In mammals, it plays a key role…”
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Mechanisms of Monomeric and Dimeric Glycogenin Autoglucosylation by Issoglio, Federico M., Carrizo, María E., Romero, Jorge M., Curtino, Juan A.

“…Initiation of glucose polymerization by glycogenin autoglucosylation at Tyr-194 is required to prime de novo biosynthesis of glycogen. It has been proposed…”
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Structural and biochemical insight into glycogenin inactivation by the glycogenosis-causing T82M mutation by Carrizo, María E., Romero, Jorge M., Issoglio, Federico M., Curtino, Juan A.

“…► T82M mutation does not change contacts with UDPG and Tyr194 positioning. ► Autoglucosylation, DBM glucosylation and UDPG hydrolysis are abolished in T82M…”
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The intramolecular autoglucosylation of monomeric glycogenin by Bazán, Soledad, Issoglio, Federico M., Carrizo, María E., Curtino, Juan A.

“…The ability of monomeric glycogenin to autoglucosylate by an intramolecular mechanism of reaction is described using non-glucosylated and partially…”
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Evidence for glycogenin autoglucosylation cessation by inaccessibility of the acquired maltosaccharide by Romero, Jorge M., Issoglio, Federico M., Carrizo, María E., Curtino, Juan A.

“…Glycogenin initiates the biosynthesis of proteoglycogen, the mammalian glycogenin-bound glycogen, by intramolecular autoglucosylation. The incubation of…”
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Metabolic and Structural Insights into Hydrogen Sulfide Mis-Regulation in IEnterococcus faecalis/I by Walsh, Brenna J. C, Costa, Sofia Soares, Edmonds, Katherine A, Trinidad, Jonathan C, Issoglio, Federico M, Brito, José A, Giedroc, David P

“…Hydrogen sulfide (H[sub.2]S) is implicated as a cytoprotective agent that bacteria employ in response to host-induced stressors, such as oxidative stress and…”
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