Search Results - "Issazadeh, S."

PD-L1 expression by neurons nearby tumors indicates better prognosis in glioblastoma patients by Liu, Yawei, Carlsson, Robert, Ambjørn, Malene, Hasan, Maruf, Badn, Wiaam, Darabi, Anna, Siesjö, Peter, Issazadeh-Navikas, Shohreh

“…Glioblastoma multiforme (GBM) is the most aggressive form of brain tumor. In general, tumor growth requires disruption of the tissue microenvironment, yet how…”
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Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β by Issazadeh, S., Ljungdahl, A., Höjeberg, B., Mustafa, M., Olsson, T.

“…The kinetics of mRNA expression in the central nervous system (CNS) for a series of putatively disease-promoting and disease-limiting cytokines during the…”
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Interferon gamma, interleukin 4 and transforming growth factor beta in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells by Issazadeh, S, Mustafa, M, Ljungdahl, A, Höjeberg, B, Dagerlind, A, Elde, R, Olsson, T

“…The potential role of certain important immunoregulatory and effector cytokines in autoimmune neuroinflammation have been studied. We have examined the…”
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Major histocompatibility complex-controlled protective influences on experimental autoimmune encephalomyelitis are peptide specific by Issazadeh, S, Kjellén, P, Olsson, T, Mustafa, M, Holmdahl, R

“…The myelin basic protein (MBP) peptide 63-88-induced experimental autoimmune encephalomyelitis (EAE) and its associated T cell cytokine profile are influenced…”
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Interferon-beta regulates neuronal autophagy and attenuates Parkinson’s disease like dementia by Issazadeh-Navikas, S.

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S.05.03 - Interferon-beta regulates neuronal autophagy and attenuates Parkinson’s disease like dementia by Issazadeh-Navikas, S.

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Nasal administration of amyloid-β peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease by Weiner, Howard L., Lemere, Cynthia A., Maron, Ruth, Spooner, Edward T., Grenfell, Trelawney J., Mori, Chica, Issazadeh, Shohreh, Hancock, Wayne W., Selkoe, Dennis J.

“…Progressive cerebral deposition of amyloid‐β (Aβ) peptide, an early and essential feature of Alzheimer's disease (AD), is accompanied by an inflammatory…”
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CYTOKINE PRODUCTION IN THE CENTRAL-NERVOUS-SYSTEM OF LEWIS RATS WITH EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS - DYNAMICS OF MESSENGER-RNA EXPRESSION FOR INTERLEUKIN-10, INTERLEUKIN-12, CYTOLYSIN, TUMOR-NECROSIS-FACTOR-ALPHA AND TUMOR-NECROSIS-FACTOR-BETA by ISSAZADEH, S, LJUNGDAHL, A, HOJEBERG, B, MUSTAFA, M, OLSSON, T

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Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy by Comabella, M, Balashov, K, Issazadeh, S, Smith, D, Weiner, H L, Khoury, S J

“…Multiple sclerosis is postulated to be a Th1-type cell-mediated autoimmune disease. We investigated cytokine profiles in patients with progressive multiple…”
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Kinetics of Expression of Costimulatory Molecules and Their Ligands in Murine Relapsing Experimental Autoimmune Encephalomyelitis In Vivo by Issazadeh, Shohreh, Navikas, Vaidrius, Schaub, Meike, Sayegh, Mohamed, Khoury, Samia

“…We studied the kinetics of expression of costimulatory molecules and cytokines in the central nervous system (CNS) in murine relapsing experimental autoimmune…”
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Role of IFN-beta gene in the immune response after CpG motifs treatment in an allergy murine model by Matheu, V., Treschow, A., Teige, I., Barrios, Y., Issazadeh-Navikas, S.

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The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo by Kishimoto, K, Dong, V M, Issazadeh, S, Fedoseyeva, E V, Waaga, A M, Yamada, A, Sho, M, Benichou, G, Auchincloss, Jr, H, Grusby, M J, Khoury, S J, Sayegh, M H

“…We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (-/-) mice as recipients of fully mismatched cardiac allografts to…”
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GABA, a natural immunomodulator of T lymphocytes by Bjurstöm, Helen, Wang, JunYang, Ericsson, Ida, Bengtsson, Martin, Liu, Yawei, Kumar-Mendu, Suresh, Issazadeh-Navikas, Shohreh, Birnir, Bryndis

“…Abstract γ-aminobutyric acid (GABA) is the main neuroinhibitory transmitter in the brain. Here we show that GABA in the extracellular space may affect the fate…”
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pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation by Duraes, Fernanda V, Lippens, Carla, Steinbach, Karin, Dubrot, Juan, Brighouse, Dale, Bendriss-Vermare, Nathalie, Issazadeh-Navikas, Shohreh, Merkler, Doron, Hugues, Stephanie

“…Abstract Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly…”
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Innate and adaptive stimulation of murine diverse NKT cells result in distinct cellular responses by Tripathi, Prabhanshu, Sedimbi, Saikiran K., Singh, Avadhesh Kumar, Löfbom, Linda, Issazadeh‐Navikas, Shohreh, Weiss, Siegfried, Förster, Irmgard, Karlsson, Mikael C. I., Yrlid, Ulf, Kadri, Nadir, Cardell, Susanna L.

“…Natural killer T (NKT) cells recognize glycolipids presented on CD1d. They share features of adaptive T lymphocytes and innate NK cells, and mediate…”
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Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-β by Issazadeh, Shohreh, Lorentzen, Johnny C., Mustafa, Maha I., Höjeberg, Bo, Miissener, Åsa, Olsson, Tomas

“…Experimental autoimmune encephalomyelitis (EAE) in rats is typically a brief and monophasic disease with sparse demyelination. However, inbred DA rats develop…”
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Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's adjuvant by Lorentzen, Johnny C., Issazadeh, Shohreh, Storch, M., Mustafa, Maha I., Lassman, Hans, Linington, Christopher, Klareskog, Lars, Olsson, Tomas

“…Experimental autoimmune encephalomyelitis (EAE) is a model for multiple sclerosis (MS). However, MS is a chronic, relapsing and demyelinating disease, whereas…”
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IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis by Teige, Ingrid, Treschow, Alexandra, Teige, Anna, Mattsson, Ragnar, Navikas, Vaidrius, Leanderson, Tomas, Holmdahl, Rikard, Issazadeh-Navikas, Shohreh

“…Since the basic mechanisms behind the beneficial effects of IFN-beta in multiple sclerosis (MS) patients are still obscure, here we have investigated the…”
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Acquired Thymic Tolerance: Role of CTLA4 in the Initiation and Maintenance of Tolerance in a Clinically Relevant Autoimmune Disease Model by Issazadeh, Shohreh, Zhang, ManHua, Sayegh, Mohamed H, Khoury, Samia J

“…Injection of Ag into the thymus of adult animals induces specific systemic tolerance. The mechanisms of acquired thymic tolerance include anergy and the…”
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Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis by Issazadeh, S, Abdallah, K, Chitnis, T, Chandraker, A, Wells, A D, Turka, L A, Sayegh, M H, Khoury, S J

“…The mechanisms of chronic disease and recovery from relapses in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, are…”
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