Search Results - "Issabekova, Assel"

Mesenchymal Stem Cell-Based Therapy for Rheumatoid Arthritis by Sarsenova, Madina, Issabekova, Assel, Abisheva, Saule, Rutskaya-Moroshan, Kristina, Ogay, Vyacheslav, Saparov, Arman

“…Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of cells, including but not limited to, adipocytes, chondrocytes and…”
Get full text

Clinical heterogeneity in Fabry disease: A clinical case by Issabekova, Assel, Mashkunova, Olga

“…Fabry disease is an orphan lysosomal storage disease characterized by progressive organ damage. Considering that the disease is rare, the low awareness of…”
Get full text

Role of the immune system in cardiac tissue damage and repair following myocardial infarction by Saparov, Arman, Ogay, Vyacheslav, Nurgozhin, Talgat, Chen, William C. W., Mansurov, Nurlan, Issabekova, Assel, Zhakupova, Jamilya

“…Introduction The immune system plays a crucial role in the initiation, development, and resolution of inflammation following myocardial infarction (MI). The…”
Get full text

Regeneration of Osteochondral Defects by Combined Delivery of Synovium-Derived Mesenchymal Stem Cells, TGF-β1 and BMP-4 in Heparin-Conjugated Fibrin Hydrogel by Sarsenova, Madina, Raimagambetov, Yerik, Issabekova, Assel, Karzhauov, Miras, Kudaibergen, Gulshakhar, Akhmetkarimova, Zhanar, Batpen, Arman, Ramankulov, Yerlan, Ogay, Vyacheslav

“…The regeneration of cartilage and osteochondral defects remains one of the most challenging clinical problems in orthopedic surgery. Currently,…”
Get full text

Prevalence, incidence, gender and age distribution, and economic burden of psoriasis worldwide and in Kazakhstan by Dairov, Aidar, Issabekova, Assel, Sekenova, Aliya, Shakhatbayev, Miras, Ogay, Vyacheslav

“…Aim: This study aimed to conduct a literature review on the prevalence, incidence, gender and age distribution of psoriasis, as well as the economic burden of…”
Get full text

TNF-α Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in an Experimental Model of Atherosclerosis by Sekenova, Aliya, Li, Yelena, Issabekova, Assel, Saparov, Arman, Ogay, Vyacheslav

“…Atherosclerosis (AS) is an inflammatory disease involving multiple factors in its initiation and development. In recent years, the potential application of…”
Get full text

Repair of Rat Calvarial Critical-Sized Defects Using Heparin-Conjugated Fibrin Hydrogel Containing BMP-2 and Adipose-Derived Pericytes by Kudaibergen, Gulshakhar, Mukhlis, Sholpan, Mukhambetova, Ainur, Issabekova, Assel, Sekenova, Aliya, Sarsenova, Madina, Temirzhan, Abay, Baidarbekov, Murat, Umbayev, Baurzhan, Ogay, Vyacheslav

“…The repair of critical-sized calvarial defects is a challenging problem for orthopedic surgery. One of the promising strategies of bone bioengineering to…”
Get full text

The Therapeutic Potential of Pericytes in Bone Tissue Regeneration by Issabekova, Assel, Kudaibergen, Gulshakhar, Sekenova, Aliya, Dairov, Aidar, Sarsenova, Madina, Mukhlis, Sholpan, Temirzhan, Abay, Baidarbekov, Murat, Eskendirova, Saule, Ogay, Vyacheslav

“…Pericytes, as perivascular cells, are present in all vascularized organs and tissues, and they actively interact with endothelial cells in capillaries and…”
Get full text

Structural and functional characteristics of the heart before and after CRT in patients with heart failure by Akhyt, Bagdat, Kuanyshbekova, Roza, Madaliyev, Kurmangazy, Mussagaliyeva, Aisulu, Koshumbayeva, Kulzida, Issabekova, Assel, Atageldiyeva, Kuralay

“…The aim of the study was to evaluate the clinical and hemodynamic effects of resynchronization therapy in patients with congestive heart failure. Materials and…”
Get full text

Immunomodulatory Effects of Plant Extracts from Salvia deserta Schang. and Salvia sclarea L by Zhussupova, Aizhan, Zhumaliyeva, Gaziza, Ogay, Vyacheslav, Issabekova, Assel, Ross, Samir A, Zhusupova, Galiya E

“…Medicines, their safety, effectiveness and quality are indispensable factors of national security, important on a global scale. The COVID-19 pandemic has once…”
Get full text

139 Identifying neoantigens in lung adenocarcinoma patients by Chang, Andrew C, Xin, Ying, Issabekova, Assel, McEwen, Dyke, Gensterblum-Miller, Elizabeth, Chad Brenner, J, Dobson, Hannah, Chang, Alfred E, Li, Qiao

“…BackgroundIdentification of neoepitopes/neoantigens represents a novel approach to cancer immunotherapy. In this study, we identified and characterized…”
Get full text

Risk factors of chronic noncommunicable diseases comorbidity in South-Kazakhstan region by Urazalina, Saule, Musagalieva, Aisulu, Issabekova, Assel, Koshumbayeva, Kulzida, Akhit, Bagdat

“…Aim: To conduct a one-stage multicenter study in South-Kazakhstan Region to obtain baseline prevalence of comorbidity of chronic noninfectious diseases and…”
Get full text

Heparin-Conjugated Fibrin Hydrogel with Chondroinductive Growth Factors and Human Synovium-Derived Mesenchymal Stem Cells for the Treatment of Articular Cartilage Defects: Evaluation of Clinical Safety by Toktarov, Tusipkhan, Saginov, Bakhtiyar, Raimagambetov, Yerik, Balbossynov, Bagdat, Korganbekova, Gulzhanat, Urazayev, Marat, Issabekova, Assel, Zhubanova, Gulsamal, Kaukabayeva, Guldarigash, Sekenova, Aliya, Kudaibergen, Gulshakhar, Akhmetkarimova, Zhanar, Eskendirova, Saule, Ramankulov, Yerlan, Bekarissov, Olzhas, Batpen, Arman, Ogay, Vyacheslav

“…The purpose of this study was to evaluate the safety of an injectable heparin-conjugated fibrin (HCF) hydrogel containing human synovium-derived mesenchymal…”
Get full text

miR-1279, miR-548j, miR-548m, and miR-548d-5p Binding Sites in CDSs of Paralogous and Orthologous PTPN12, MSH6, and ZEB1 Genes by Ivashchenko, Anatoly, Berillo, Olga, Issabekova, Assel S.

“…Only PTPN12, MSH6, and ZEB1 have significant miR-1279 binding sites among paralogous genes of human tyrosine phosphatase family, DNA mismatch repair family,…”
Get full text

Psoriasis: The Versatility of Mesenchymal Stem Cell and Exosome Therapies by Dairov, Aidar, Sekenova, Aliya, Alimbek, Symbat, Nurkina, Assiya, Shakhatbayev, Miras, Kumasheva, Venera, Kuanysh, Sandugash, Adish, Zhansaya, Issabekova, Assel, Ogay, Vyacheslav

“…Mesenchymal stem cells (MSCs) are multilineage differentiating stromal cells with extensive immunomodulatory and anti-inflammatory properties. MSC-based…”
Get full text

Monoclonal Antibodies for Immunohistochemical Diagnosis of Breast Cancer by Turgimbayeva, Aigerim, Issabekova, Assel, Zhylkibayev, Assylbek, Eskendirova, Saule

“…Breast cancer is a leading malignant disease in women worldwide, although its pathology is visually localised. Currently, it has been proven that the…”
Get full text

The Crosstalk Between Dendritic Cells, Cytokine-Induced Killer Cells And Cancer Cells From The Perspective Of Combination Therapy by Issabekova, Assel, Zhumabekova, Marzhan, Zhunussova, Madina, Ogay, Vyacheslav

“…Dendritic cells (DCs) are considered the most potent professional antigen-presenting cells (APCs) that elicit adaptive antitumour immunity. DCs integrate…”
Get full text

Immunomodulatory Effects of Plant Extracts from ISalvia deserta/I Schang. and ISalvia sclarea/I L by Zhussupova, Aizhan, Zhumaliyeva, Gaziza, Ogay, Vyacheslav, Issabekova, Assel, Ross, Samir A, Zhusupova, Galiya E

“…Medicines, their safety, effectiveness and quality are indispensable factors of national security, important on a global scale. The COVID-19 pandemic has once…”
Get full text

Characteristics of binding sites of intergenic, intronic and exonic miRNAs with mRNAs of oncogenes coding intronic miRNAs by Berillo, O A, Issabekova, A S, Regnier, M, Ivashchenko, A T

“…The interaction of 784 intergenic (ig-miRNA), 686 intronic (in-miRNA) and 49 exonic miRNAs (ex-miRNA) with mRNAs of 51 oncogenes coding in-miRNAs was…”
Get full text

Interactions of intergenic microRNAs with mRNAs of genes involved in carcinogenesis by Issabekova, Assel, Berillo, Olga, Regnier, Mireille, Anatoly, Ivashchenko

“…miRNAs regulate gene expression by binding with mRNAs of many genes. Studying their effects on genes involved in oncogenesis is important in cancer diagnostics…”
Get full text