Search Results - "Issa, Razao"

Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia by Williams, Alison S, Leung, Sum-Yee, Nath, Puneeta, Khorasani, Nadia M, Bhavsar, Pankaj, Issa, Razao, Mitchell, Jane A, Adcock, Ian M, Chung, Kian Fan

“…1 Experimental Studies and Airway Disease Section and 2 Cardiothoracic Medicine Section, National Heart and Lung Institute, Imperial College, London, United…”
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CD105 prevents apoptosis in hypoxic endothelial cells by Li, Chenggang, Issa, Razao, Kumar, Pat, Hampson, Ian N, Lopez-Novoa, Jose M, Bernabeu, Carmelo, Kumar, Shant

“…CD105, a marker of endothelial cells, is abundantly expressed in tissues undergoing angiogenesis and is a receptor for transforming growth factorbeta. The…”
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Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125 by Williams, Alison S, Issa, Razao, Leung, Sum Yee, Nath, Puneeta, Ferguson, Gregory D, Bennett, Brydon L, Adcock, Ian M, Chung, Kian Fan

“…Ozone has potent oxidizing properties, and exposure to ozone causes airway hyper-responsiveness (AHR) and lung inflammation. We determined the importance of…”
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Induction and regulation of matrix metalloproteinase-12in human airway smooth muscle cells by Xie, Shaoping, Issa, Razao, Sukkar, Maria B, Oltmanns, Ute, Bhavsar, Pankaj K, Papi, Alberto, Caramori, Gaetano, Adcock, Ian, Fan Chung, K

“…Abstract Background The elastolytic enzyme matrix metalloproteinase (MMP)-12 has been implicated in the development of airway inflammation and remodeling. We…”
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Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation by Williams, Alison S., Issa, Razao, Durham, Andrew, Leung, Sum-Yee, Kapoun, Ann, Medicherla, Satyanarayana, Higgins, Linda S., Adcock, Ian M., Chung, Kian Fan

“…Ozone is a potent oxidant and causes airway hyperresponsiveness and neutrophilia. To determine the role of p38 mitogen-activated protein kinase (MAPK)…”
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Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation by Trim, Nathan, Morgan, Sue, Evans, Martyn, Issa, Razao, Fine, David, Afford, Simon, Wilkins, Bridget, Iredale, John

“…We have examined the expression of p75, a member of the TNF receptor superfamily in hepatic stellate cells (HSC) and pancreatic stellate cells (PSC). Activated…”
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Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells by Gaça, Marianna D.A., Zhou, Xiaoying, Issa, Razao, Kiriella, Kishanee, Iredale, John P., Benyon, R.Christopher

“…During liver fibrosis hepatic stellate cells become activated, transforming into proliferative myofibroblastic cells expressing type I collagen and α-smooth…”
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Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells by Issa, Razao, Sorrentino, Rosalinda, Sukkar, Maria B, Sriskandan, Shiranee, Chung, Kian Fan, Mitchell, Jane A

“…Bacterial infections are a cause of exacerbation of airway disease. Airway smooth muscle cells (ASMC) are a source of inflammatory cytokines/chemokines that…”
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Role of c‐jun N‐terminal kinase in the induced release of GM‐CSF, RANTES and IL‐8 from human airway smooth muscle cells by Oltmanns, Ute, Issa, Razao, Sukkar, Maria B, John, Matthias, Chung, K Fan

“…Human airway smooth muscle cells (HASMC) contribute to airway inflammation in asthma by virtue of their capacity to produce several inflammatory mediators…”
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Expression of basic fibroblast growth factor mRNA and protein in the human brain following ischaemic stroke by ISSA, Razao, ALQTEISHAT, Ahmed, MITSIOS, Nick, SAKA, Mohamad, KRUPINSKI, Jerzy, TARKOWSKI, Elizabeth, GAFFNEY, John, SLEVIN, Mark, KUMAR, Shant, KUMAR, Pat

“…Our previous work has demonstrated that angiogenesis occurs in the damaged brain tissue of patients surviving acute ischaemic stroke and increased microvessel…”
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A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans by KRUPINSKI, J, ISSA, R, BUJNY, T, SLEVIN, M, KUMAR, P, KUMAR, S, KALUZA, J

“…Growth factors control two important processes in infarcted tissue, ie, angiogenesis and gliosis. We recently reported that transforming growth factor-beta1…”
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Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Tissue Inhibitor of Metalloproteinase-1 Is Mediated via Effects on Matrix Metalloproteinase Inhibition by Murphy, Frank R., Issa, Razao, Zhou, Xiaoying, Ratnarajah, Shabna, Arthur, Michael J.P., Benyon, Christopher, Iredale, John P., Nagase, Hideaki

“…The activated hepatic stellate cell (HSC) is central to liver fibrosis as the major source of collagens I and III and the tissue inhibitors of…”
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Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta by Xie, Shaoping, Sukkar, Maria B, Issa, Razao, Khorasani, Nadia M, Chung, Kian Fan

“…Airway smooth muscle (ASM) hyperplasia is a characteristic feature of the asthmatic airway, but the underlying mechanisms that induce ASM hyperplasia remain…”
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Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration by Issa, Razao, Zhou, Xiaoying, Trim, Nathan, Millward-Sadler, Harry, Krane, Stephen, Benyon, Christopher, Iredale, John

“…Collagen-I, which predominates in the neomatrix of fibrotic liver, regulates hepatocyte and hepatic stellate cell (HSC) phenotypes. Recovery from liver…”
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Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer's disease and vascular dementia by TARKOWSKI, Elisabeth, ISSA, Razao, SJÖGREN, Magnus, WALLIN, Anders, BLENNOW, Kaj, TARKOWSKI, Andrej, KUMAR, Pat

“…The aim of the present study was to investigate, in patients with Alzheimer's disease (AD), and vascular dementia (VAD), patterns of local release of vascular…”
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Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking by Issa, Razao, Zhou, Xiaoying, Constandinou, Christothea M., Fallowfield, Jonathan, Millward-Sadler, Harry, Gaca, Marianna D.A., Sands, Emma, Suliman, Ibnauf, Trim, Nathan, Knorr, Andreas, Arthur, Michael J.P., Benyon, R.Christopher, Iredale, John P.

“…Background & Aims: Liver fibrosis and cirrhosis result from the excessive secretion of matrix proteins by hepatic stellate cells (HSCs). Previously considered…”
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Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells by Issa, Razao, Xie, Shaoping, Khorasani, Nadia, Sukkar, Maria, Adcock, Ian M, Lee, Kang-Yun, Chung, Kian Fan

“…Expression of the inflammatory chemokine, growth-related oncogene protein-alpha (GRO-alpha), from airway smooth muscle cells (ASMC) is regulated by pathways…”
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Tissue Inhibitor of Metalloproteinase-1 Inhibits Apoptosis of Rat and Human Hepatic Stellate Cells In Vitro by Murphy, Frank R, Issa, Razao, Benyon, Christopher, Iredale, John P

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Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis by Murphy, Frank R, Issa, Razao, Zhou, Xiaoying, Ratnarajah, Shabna, Nagase, Hideaki, Arthur, Michael J P, Benyon, Christopher, Iredale, John P

“…The activated hepatic stellate cell (HSC) is central to liver fibrosis as the major source of collagens I and III and the tissue inhibitors of…”
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Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle by Sukkar, Maria B., Xie, Shaoping, Khorasani, Nadia M., Kon, Onn Min, Stanbridge, Rex, Issa, Razao, Chung, Kian Fan

“…Host defense against microbial pathogens is elicited through the innate immune system by means of Toll-like receptors (TLRs). Airway smooth muscle cells…”
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