Search Results - "Isola, J J"

Differences in body temperature between black-and-white and red-and-white Holstein cows reared on a hot climate using infrared thermography by Isola, J.V.V., Menegazzi, G., Busanello, M., dos Santos, S.B., Agner, H.S.S., Sarubbi, J.

“…Heat stress is one of the greatest issues of the dairy industry in regions with hot climate. Since coat color appears to be related to heat stress…”
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Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIα gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab by Tanner, M., Hollmén, M., Junttila, T. T., Kapanen, A. I., Tommola, S., Soini, Y., Helin, H., Salo, J., Joensuu, H., Sihvo, E., Elenius, K., Isola, J.

“…Background:HER-2/neu gene amplification has predictive value in breast cancer patients responding to trastuzumab. We wanted to investigate the frequency and…”
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Assessment of PARP protein expression in epithelial ovarian cancer by ELISA pharmacodynamic assay and immunohistochemistry by Veskimäe, K., Staff, S., Grönholm, A., Pesu, M., Laaksonen, M., Nykter, M., Isola, J., Mäenpää, J.

“…Targeting Poly (ADP-ribose) polymerase 1 (PARP-1) involved in base excision repair (BER) has been shown to be a clinically effective treatment strategy in…”
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Frequent Amplification of Chromosomal Region 20q12-q13 in Ovarian Cancer by Tanner, M M, Grenman, S, Koul, A, Johannsson, O, Meltzer, P, Pejovic, T, Borg, A, Isola, J J

“…DNA amplification at chromosomal region 20q12-q13, which is common in breast cancer, has recently been described also in ovarian tumors. We studied the…”
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Exogenous sex hormone use and risk of meningioma: a population-based case-control study in Finland by Korhonen, K., Raitanen, J., Isola, J., Haapasalo, H., Salminen, T., Auvinen, A.

“…Background Previous studies on association of exogenous female sex hormones and risk for meningioma have yielded conflicting results. The aim of this study was…”
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Dual-colour chromogenic in situ hybridization for testing of HER-2 oncogene amplification in archival breast tumours by Laakso, M, Tanner, M, Isola, J

“…Chromogenic in situ hybridization (CISH), which uses an enzymatic reaction to detect the hybridized DNA probe, is a new alternative to fluorescence in situ…”
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Lumpectomy with or without postoperative radiotherapy for breast cancer with favourable prognostic features: results of a randomized study by HOLLI, K, SAARISTO, R, ISOLA, J, JOENSUU, H, HAKAMA, M

“…The aim of this trial was to study the value of adding post-operative radiotherapy to lumpectomy in a subgroup of breast cancer patients with favourable…”
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A digital atlas of breast histopathology: an application of web based virtual microscopy by Lundin, M, Lundin, J, Helin, H, Isola, J

“…Aims: To develop an educationally useful atlas of breast histopathology, using advanced web based virtual microscopy technology. Methods: By using a robotic…”
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Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization by VISAKORPI, T, KALLIONIEMI, A. H, SYVÄNEN, A.-C, HYYTINEN, E. R, KARHU, R, TAMMELA, T, ISOLA, J. J, KALLIONIEMI, O.-P

“…Genetic changes leading to the development of prostate cancer and factors that underlie the clinical progression of the disease are poorly characterized. Here,…”
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Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy by Kuukasjärvi, T, Kononen, J, Helin, H, Holli, K, Isola, J

“…Up to 30% to 40% of metastases from hormone receptor-positive primary breast cancer do not respond to endocrine therapy. We studied how often hormone receptor…”
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Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer by Isola, JJ, Kallioniemi, OP, Chu, LW, Fuqua, SA, Hilsenbeck, SG, Osborne, CK, Waldman, FM

“…Breast cancer progression is determined by a complex pattern of multiple genetic aberrations the association of which with patient prognosis is unknown. In…”
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Very high quantitative tumor HER2 content and outcome in early breast cancer by Joensuu, H., Sperinde, J., Leinonen, M., Huang, W., Weidler, J., Bono, P., Kataja, V., Kokko, R., Turpeenniemi-Hujanen, T., Jyrkkiö, S., Isola, J., Kellokumpu-Lehtinen, P.-L., Paquet, A., Lie, Y., Bates, M.

“…It is unknown how a very high tumor total HER2 (human epidermal growth factor receptor-2) content (H2T) influences outcome in early breast cancer treated with…”
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Overall and worst gleason scores are equally good predictors of prostate cancer progression by Tolonen, Teemu T, Kujala, Paula M, Tammela, Teuvo L J, Tuominen, Vilppu J, Isola, Jorma J, Visakorpi, Tapio

“…Gleason scoring has experienced several modifications during the past decade. So far, only one study has compared the prognostic abilities of worst (WGS) and…”
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Immunohistochemical demonstration of androgen receptor in breast cancer and its relationship to other prognostic factors by Isola, J J

“…Androgen actions and androgen receptors (ARs) have been described in human breast cancer cells both in vivo and in vitro. With the use of a new monoclonal…”
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p-53 gene mutations as a predictive marker in a population of advanced breast cancer patients randomly treated with doxorubicin or docetaxel in the context of a phase III clinical trial by Di Leo, A, Tanner, M, Desmedt, C, Paesmans, M, Cardoso, F, Durbecq, V, Chan, S, Perren, T, Aapro, M, Sotiriou, C, Piccart, MJ, Larsimont, D, Isola, J

“…Background: Preclinical data indicate that p-53 gene mutations predict resistance to doxorubicin (A) but not to docetaxel (Taxotere) (T). In the TAX 303 trial,…”
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Geological and Geophysical Investigation of Contourite Systems from the Central and Southern Atlantic during Cruise 52 of the R/V Akademik Ioffe by Ivanova, E. V., Murdmaa, I. O., Borisov, D. G., Simagin, N. V., Ovsepyan, E. A., Libina, N. V., Isola, J. I., Bulycheva, E. V., Shulga, N. A., Krek, A. V., Lobus, N. V., Lapidus, L. V.

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Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients by Juuti-Uusitalo, K, Mäki, M, Kainulainen, H, Isola, J, Kaukinen, K

“…In coeliac disease gluten induces an immunological reaction in genetically susceptible patients, and influences on epithelial cell proliferation and…”
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Low biologic aggressiveness in breast cancer in women using hormone replacement therapy by Holli, K, Isola, J, Cuzick, J

“…Hormone replacement therapy (HRT) has been associated with an increased risk for breast cancer. Cancers in women who use HRT are often less advanced, and lower…”
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A public-domain image processing tool for automated quantification of fluorescence in situ hybridisation signals by Konsti, J, Lundin, J, Jumppanen, M, Lundin, M, Viitanen, A, Isola, J

“…To develop and evaluate an automated method for quantification of HER2 fluorescence in situ hybridisation (FISH) signals. Using a popular, open source image…”
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Reduced E-cadherin expression is associated with invasiveness and unfavorable prognosis in breast cancer by SIITONEN, S. M, KONONEN, J. T, HELIN, H. J, RANTALA, I. S, HOLLI, K. A, ISOLA, J. J

“…E-cadherin (E-cad) is a calcium-dependent, epithelial cell adhesion molecule whose reduced or lost expression has been associated with tumor dedifferentiation…”
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