Search Results - "Isola, Allison"

Exosomes: The Messengers of Health and Disease by Isola, Allison L, Chen, Suzie

“…Exosomes are small vesicles comprised of a lipid bilayer containing various proteins, RNAs and bioactive lipids. They act as intercellular messengers that give…”
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Biology, Therapy and Implications of Tumor Exosomes in the Progression of Melanoma by Isola, Allison L, Eddy, Kevinn, Chen, Suzie

“…Cancer is the second leading cause of death in the United States, and about 6% of the estimated cancer diagnoses this year will be melanoma cases. Melanomas…”
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Methylation of Histone H3 on Lysine 4 by the Lysine Methyltransferase SET1 Protein Is Needed for Normal Clock Gene Expression by Raduwan, Hamidah, Isola, Allison L., Belden, William J.

“…The circadian oscillator controls time-of-day gene expression by a network of interconnected feedback loops and is reset by light. The requisite for chromatin…”
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Exosomes released by metabotropic glutamate receptor 1 (GRM1) expressing melanoma cells increase cell migration and invasiveness by Isola, Allison L, Eddy, Kevinn, Zembrzuski, Krzysztof, Goydos, James S, Chen, Suzie

“…Exosomes are naturally occurring membrane-bound nanovesicles generated constitutively and released by various cell types, and often in higher quantities by…”
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Exosomes: The Link between GPCR Activation and Metastatic Potential? by Isola, Allison L, Chen, Suzie

“…The activation of G-Protein Coupled Receptors (GPCRs) by their respective ligands initiates a cascade of multiple signaling processes within the cell,…”
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A Spontaneous Melanoma Mouse Model Applicable for a Longitudinal Chemotherapy and Immunotherapy Study by Eddy, Kevinn, Gupta, Kajal, Pelletier, Jeffrey C., Isola, Allison L., Marinaro, Christina, Rasheed, Maryam Abdur, Campagnolo, Joseph, Eddin, Mohamad Naser, Rossi, Marco, Fateeva, Anna, Reuhl, Kenneth, Shah, Raj, Robinson, Ann K., Chaly, Anna, Freeman, Katie B., Chen, Wenjin, Diaz, Jesus, Furmanski, Philip, Silk, Ann W., Reitz, Allen B., Zloza, Andrew, Chen, Suzie

“…Mouse models that reflect human disorders provide invaluable tools for the translation of basic science discoveries to clinical therapies. However, many of…”
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Current frameworks for environmental and health assessment of hydrocarbon streams and products are flexible and ready for alternative non crude oil-based feeds by Lampi, Mark A, Therkorn, Jennifer H, Kung, Ming H, Isola, Allison L, Barter, Robert A

“…Hazard and risk assessment of complex petroleum-derived substances has been in a state of continuous improvement since the 1970s, with the development of…”
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Extracellular vesicles: important players in immune homeostasis by Isola, Allison L, Chen, Suzie

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Comparison of PAC and MOAH for understanding the carcinogenic and developmental toxicity potential of mineral oils by Carrillo, Juan-Carlos, Kamelia, Lenny, Romanuka, Julija, Kral, Olaf, Isola, Allison, Niemelä, Helena, Steneholm, Anna

“…The carcinogenicity and developmental toxicity of unrefined mineral oil is related to its 3–7 ring polycyclic aromatic compounds (PAC) content. Therefore,…”
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Abstract 4199: Riluzole modulates the production of exosomes in melanoma cells by Isola, Allison L., Wen, Yvonne, Goydos, James, Chen, Suzie

“…Abstract Exosomes are naturally occurring small membrane enclosed microvesicles generated constitutively and released by various cell types and more frequently…”
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GRM1 to induce M-CSF and CCL2 expression to lead to an upregulation of M2 macrophages in melanoma by Li, Jiadong, Wen, Yu, Jeong, Byeong-Seon, Shah, Raj, Isola, Allison, Silk, Ann W., Chen, Suzie, Goydos, James Steven

“…Abstract only 122 Background: GRM1 transgenic mice in an immune competent background (C57BL6) develope melanoma with 100% penetrance (TG-3 mice). Ectopic…”
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Role of GRM1 in Exosome Production and Melanoma Metastasis by Isola, Allison L

“…Exosomes are naturally occurring membrane-bound nanovesicles generated constitutively and released by various cell types, and often in higher quantities by…”
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