Search Results - "Isobe, Takeshi"

Morse–Floer theory for superquadratic Dirac-geodesics by Isobe, Takeshi, Maalaoui, Ali

“…In this paper we present the full details of the construction of a Morse–Floer type homology related to the superquadratic perturbation of the Dirac-geodesic…”
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Anticancer Activity of ZnO Nanoparticles against Human Small-Cell Lung Cancer in an Orthotopic Mouse Model by Tanino, Ryosuke, Amano, Yoshihiro, Tong, Xuexia, Sun, Rong, Tsubata, Yukari, Harada, Mamoru, Fujita, Yasuhisa, Isobe, Takeshi

“…Small-cell lung cancer, a highly malignant form of lung cancer, often responds to first-line treatments but relapses in most cases with resistance to further…”
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Morse–Floer theory for superquadratic Dirac equations, I: relative Morse indices and compactness by Isobe, Takeshi

“…In this paper and its sequel (Isobe in Morse–Floer theory for superquadratic Dirac equations, II: construction and computation of Morse–Floer homology, 2016 ),…”
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Morse–Floer theory for superquadratic Dirac equations, II: construction and computation of Morse–Floer homology by Isobe, Takeshi

“…We give a construction and computation of Morse–Floer homology for a class of superquadratic Dirac functionals defined on the set of spinors on a compact spin…”
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Pemetrexed sensitizes human lung cancer cells to cytotoxic immune cells by Okimoto, Tamio, Kotani, Hitoshi, Iida, Yuichi, Koyanagi, Akira, Tanino, Ryosuke, Tsubata, Yukari, Isobe, Takeshi, Harada, Mamoru

“…Pemetrexed (PEM) is a useful drug that can be combined with immune checkpoint blockade therapy for treatment of patients with advanced non–small‐cell lung…”
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Existence results for solutions to nonlinear Dirac equations on compact spin manifolds by Isobe, Takeshi

“…We consider super-linear and sub-linear nonlinear Dirac equations on compact spin manifolds. Their solutions are obtained as critical points of certain…”
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Protein tyrosine kinase 2: a novel therapeutic target to overcome acquired EGFR-TKI resistance in non-small cell lung cancer by Tong, Xuexia, Tanino, Ryosuke, Sun, Rong, Tsubata, Yukari, Okimoto, Tamio, Takechi, Mayumi, Isobe, Takeshi

“…Protein tyrosine kinase 2 (PTK2) expression has been reported in various types of human epithelial cancers including lung cancer; however, the role of PTK2 in…”
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Current Therapeutic Strategies and Prospects for EGFR Mutation-Positive Lung Cancer Based on the Mechanisms Underlying Drug Resistance by Tsubata, Yukari, Tanino, Ryosuke, Isobe, Takeshi

“…The discovery of activating mutations in the epidermal growth factor receptor ( ) gene and the development of EGFR tyrosine kinase inhibitors (TKIs) have led…”
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Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer by Hotta, Takamasa, Nariai, Yuko, Kajitani, Naoyo, Kadota, Kyuichi, Maruyama, Riruke, Tajima, Yoshitsugu, Isobe, Takeshi, Kamino, Hiroki, Urano, Takeshi

“…Despite recent advances in cancer treatments, pancreatic cancer has a dismal prognosis globally. Early detection of cancer cells and effective treatments for…”
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Deep learning-based diagnosis from endobronchial ultrasonography images of pulmonary lesions by Hotta, Takamasa, Kurimoto, Noriaki, Shiratsuki, Yohei, Amano, Yoshihiro, Hamaguchi, Megumi, Tanino, Akari, Tsubata, Yukari, Isobe, Takeshi

“…Endobronchial ultrasonography with a guide sheath (EBUS-GS) improves the accuracy of bronchoscopy. The possibility of differentiating benign from malignant…”
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Ultra-magnifying Imaging of Thoracoscopic Biopsy Specimens Using Ex vivo Endocytoscopy in Three Patients with Mesothelioma by Shiratsuki, Yohei, Kurimoto, Noriaki, Amano, Yoshihiro, Hamaguchi, Shunichi, Kobayashi, Misato, Okuno, Takae, Hotta, Takamasa, Tsubata, Yukari, Isobe, Takeshi

“…We performed endocytoscopy (ECS) for the ex vivo evaluation of mesothelioma in specimens biopsied during medical thoracoscopy in three patients. We evaluated…”
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Cytokine Release Syndrome More than Two Years after Pembrolizumab Introduction by Nakashima, Kazuhisa, Kitani, Kashu, Kono, Kento, Yoshihara, Ken, Kawakado, Keita, Kobayashi, Misato, Okuno, Takae, Amano, Yoshihiro, Tsubata, Yukari, Isobe, Takeshi

“…A 71-year-old man with advanced lung adenocarcinoma was treated with carboplatin, pemetrexed, and pembrolizumab in June 2020. Pemetrexed and pembrolizumab…”
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IgA Nephropathy that Developed as an Immune-related Adverse Event of Pembrolizumab Complicated with Interstitial Nephritis by Mitarai, Yuki, Nakashima, Kazuhisa, Fukunaga, Shohei, Ishikawa, Noriyoshi, Ito, Takafumi, Tsubata, Yukari, Isobe, Takeshi

“…A 70-year-old man received pembrolizumab as a second-line treatment for squamous cell lung cancer of the lower right lobe. After three courses, proteinuria and…”
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A Low Crizotinib Concentration in the Cerebrospinal Fluid Causes Ineffective Treatment of Anaplastic Lymphoma Kinase-positive Non-small Cell Lung Cancer with Carcinomatous Meningitis by Okimoto, Tamio, Tsubata, Yukari, Hotta, Takamasa, Hamaguchi, Megumi, Nakao, Mika, Hamaguchi, Shun-ichi, Hamada, Akinobu, Isobe, Takeshi

“…The central nervous system is a common site of relapse in patients receiving crizotinib, which is presumed to be associated with the low concentration of…”
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Lipoid Pneumonia Caused by Esophageal Achalasia by Kono, Kento, Hamaguchi, Megumi, Tanino, Akari, Nakao, Mika, Hotta, Takamasa, Amano, Yoshihiro, Kurimoto, Noriaki, Tsubata, Yukari, Isobe, Takeshi

“…A 59-year-old man presented with esophageal achalasia complicated by lipoid pneumonia. Dysphagia and diffuse ground-glass shadows on computed tomography led to…”
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Light wavelength-switchable photocatalytic reaction by gold nanoparticle-loaded titanium(IV) dioxide by Naya, Shin-ichi, Teranishi, Miwako, Isobe, Takeshi, Tada, Hiroaki

“…Surface plasmon resonance excitation of gold nanoparticle-loaded on titanium(IV) dioxide (Au/TiO(2)) by visible light (lambda > 420 nm) has led to selective…”
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Disseminated Nocardiosis Initially Manifesting as Visual Field Defects by Okimoto, Tamio, Tsubata, Yukari, Nakao, Mika, Isobe, Takeshi

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IgA Nephropathy that Developed as an Immune-related Adverse Event of Pembrolizumab Complicated with Interstitial Nephritis: A Case Study by Mitarai, Yuki, Nakashima, Kazuhisa, Fukunaga, Shohei, Ishikawa, Noriyoshi, Ito, Takafumi, Tsubata, Yukari, Isobe, Takeshi

“…A 70-year-old man received pembrolizumab as a second-line treatment for squamous cell lung cancer of the lower right lobe. After three courses, proteinuria and…”
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Comparative Analysis of the Attitudes toward Palliative Care between Medical Oncologists and Pulmonologists by Okimoto, Tamio, Tsubata, Yukari, Nakao, Mika, Hotta, Takamasa, Hamaguchi, Megumi, Hamaguchi, Shunichi, Isobe, Takeshi

“…Objective In Japan, both medical oncologists and pulmonologists treat lung cancer patients; however, the difference in their attitude toward palliative care…”
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Characterization of a spontaneous mouse model of mild, accelerated aging via ECM degradation in emphysematous lungs by Tanino, Ryosuke, Tsubata, Yukari, Hotta, Takamasa, Okimoto, Tamio, Amano, Yoshihiro, Takechi, Mayumi, Tanaka, Tetsuya, Akita, Tomomi, Nagase, Mamiko, Yamashita, Chikamasa, Wada, Koichiro, Isobe, Takeshi

“…Emphysema limits airflow and causes irreversible progression of chronic obstructive pulmonary disease (COPD). Strain differences must be considered when…”
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