Search Results - "Isobe, Koji"

Inhaled Laninamivir Octanoate as Prophylaxis for Influenza in Children by Nakano, Takashi, Ishiwada, Naruhiko, Sumitani, Tokuhito, Uemori, Mitsutoshi, Isobe, Koji

“…A single 20-mg dose of inhaled laninamivir octanoate is an effective treatment of influenza. However, the efficacy of laninamivir octanoate for the prevention…”
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Different antithrombotic properties of factor Xa inhibitor and thrombin inhibitor in rat thrombosis models by Furugohri, Taketoshi, Shiozaki, Yoko, Muramatsu, Sumie, Honda, Yuko, Matsumoto, Chikako, Isobe, Koji, Sugiyama, Nobutoshi

“…We compared the antithrombotic properties of a factor Xa inhibitor (DX-9065a) with those of a thrombin inhibitor (melagatran) in a rat disseminated…”
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In Vitro Characteristics, Anticoagulant Effects and In Vivo Antithrombotic Efficacy of a Novel, Potent and Orally Active Direct Factor Xa Inhibitor, DU-176b by Morishima, Yoshiyuki, Furugohri, Taketoshi, Isobe, Koji, Honda, Yuko, Matsumoto, Chikako, Shiozaki, Yoko, Muramatsu, Sumie, Sugiyama, Nobutoshi, Shibano, Toshiro

“…Factor Xa (FXa) is a key serine protease in the coagulation cascade and is a promising target enzyme for developing a new antithrombotic agent. Our first…”
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Long-acting Neuraminidase Inhibitor Laninamivir Octanoate as Post-exposure Prophylaxis for Influenza by Kashiwagi, Seizaburo, Watanabe, Akira, Ikematsu, Hideyuki, Uemori, Mitsutoshi, Awamura, Shinichiro

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The Genotype Combination of the P2Y12 Gene Might Confer Greater Risk for Coronary Artery Disease by Isobe, Koji, Matsubara, Yumiko, Takahashi, Shinichi, Uchida, Toshihiro, Ishihara, Hiroaki, Shibano, Toshiro, Ishikawa, Mie, Matsushita, Kenichi, Iwanaga, Shiro, Ogawa, Satosh, Watanabe, Gentaro, Ikeda, Yasuo, Murata, Mitsuru

“…BACKGROUND: The adenosine diphosphate (ADP) receptor P2Y12 plays a central role in platelet function, and this receptor is therapeutic target for thrombotic…”
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Antithrombotic and Hemorrhagic Effects of DU-176b, a Novel, Potent and Orally Active Direct Factor Xa Inhibitor: A Wider Safety Margin Compared to Heparins and Warfarin by Furugohri, Taketoshi, Honda, Yuko, Matsumoto, Chikako, Isobe, Koji, Sugiyama, Nobutoshi, Morishima, Yoshiyuki, Shibano, Toshiro

“…DU-176b is a novel potent, orally active and selective direct inhibitor of factor Xa (FXa). Direct FXa inhibitors have been reported to exert little effect on…”
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The Genotypic Combination of Homozygous Carriers of Both H1 Haplotype and 34C Shows a Significantly Lower Responsiveness to ADP-Induced Platelet Aggregation Than Others in Healthy Volunteers by Isobe, Koji, Matsubara, Yumiko, Takahashi, Shinichi, Iwashita, Miho, Komine, Risa, Shimizu, Aya, Uchida, Toshihiro, Ishihara, Hiroaki, Shibano, Toshiro, Watanabe, Gentaro, Ikeda, Yasuo, Murata, Mitsuru

“…BACKGROUND: The adenosine diphosphate (ADP) receptor, P2Y12, plays a central role in platelet activation and its blocker clopidogrel reduces the incidence of…”
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