Search Results - "Ismail, Tayaba"
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Interplay Between Mitochondrial Peroxiredoxins and ROS in Cancer Development and Progression
Published in International journal of molecular sciences (07-09-2019)“…Mitochondria are multifunctional cellular organelles that are major producers of reactive oxygen species (ROS) in eukaryotes; to maintain the redox balance,…”
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Comparative Analysis of the Developmental Toxicity in Xenopus laevis and Danio rerio Induced by Al2O3 Nanoparticle Exposure
Published in Environmental toxicology and chemistry (01-12-2019)“…Engineered aluminum oxide nanoparticles (Al2O3 NPs) having high‐grade thermal stability and water‐dispersion properties are extensively used in different…”
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3
KDM1A microenvironment, its oncogenic potential, and therapeutic significance
Published in Epigenetics & chromatin (19-06-2018)“…The lysine-specific histone demethylase 1A (KDM1A) was the first demethylase to challenge the concept of the irreversible nature of methylation marks. KDM1A,…”
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Early life exposure to perfluorooctanesulfonate (PFOS) impacts vital biological processes in Xenopus laevis: Integrated morphometric and transcriptomic analyses
Published in Ecotoxicology and environmental safety (01-01-2024)“…Perfluorooctanesulfonate (PFOS) is a ubiquitous environmental pollutant associated with increasing health concerns and environmental hazards. Toxicological…”
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Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels
Published in Scientific reports (21-08-2017)“…Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the reduction of H 2 O 2 and alkyl…”
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Physiological effects of KDM5C on neural crest migration and eye formation during vertebrate development
Published in Epigenetics & chromatin (06-12-2018)“…Lysine-specific histone demethylase 5C (KDM5C) belongs to the jumonji family of demethylases and is specific for the di- and tri-demethylation of lysine 4…”
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The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis
Published in Biochemical and biophysical research communications (02-09-2016)“…Alternative splicing is a major mechanism regulating pattern of gene expression through the production of multiple mRNAs from a single gene transcript. Any…”
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Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis
Published in Antioxidants (12-12-2020)“…Glutathione peroxidase 3 (GPx3) belongs to the glutathione peroxidase family of selenoproteins and is a key antioxidant enzyme in multicellular organisms…”
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Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
Published in Antioxidants (17-10-2021)“…Glutathione peroxidase 1 (Gpx1) and peroxiredoxin 2 (Prdx2) belong to the thiol peroxidase family of antioxidants, and have been studied for their antioxidant…”
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Dach1 regulates neural crest migration during embryonic development
Published in Biochemical and biophysical research communications (05-07-2020)“…Dachshund 1(Dach1) is a key component of the retinal determination gene network that plays significant roles in cell fate regulation. The vertebrate homolog of…”
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Actin depolymerizing factor destrin governs cell migration in neural development during Xenopus embryogenesis
Published in Molecules and cells (01-06-2024)“…The actin-based cytoskeleton is considered a fundamental driving force for cell differentiation and development. Destrin (Dstn), a member of the…”
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Actin Depolymerizing Factor Destrin Regulates Cilia Development and Function during Vertebrate Embryogenesis
Published in Balsaeng'gwa saengsig (01-09-2024)“…The actin cytoskeleton plays fundamental roles in ciliogenesis and the actin depolymerizing factor destrin regulates actin dynamics by treadmilling actin…”
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Synthesis of novel triazoles and a tetrazole of escitalopram as cholinesterase inhibitors
Published in Bioorganic & medicinal chemistry (01-09-2015)“…[Display omitted] A novel serie of escitalopram triazoles (60–88) and a tetrazole (89) have been synthesized and subjected to a study to establish the…”
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PCNB exposure during early embryogenic development induces developmental delay and teratogenicity by altering the gene expression in Xenopus laevis
Published in Environmental toxicology (01-01-2023)“…Pentachloronitrobenzene (PCNB) is an organochlorine fungicide commonly used to treat seeds against seedling infections and controlling snow mold on golf…”
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Longipetalosides A–C, new steroidal saponins from Tribulus longipetalus
Published in Steroids (01-05-2014)“…•Three new and two known steroids were isolated from Tribulus longipetalus.•Their structures were established due to spectroscopic and spectrometric…”
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Comparative Analysis of the Developmental Toxicity in Xenopus laevis and Danio rerio Induced by Al 2 O 3 Nanoparticle Exposure
Published in Environmental toxicology and chemistry (01-12-2019)“…Engineered aluminum oxide nanoparticles (Al O NPs) having high-grade thermal stability and water-dispersion properties are extensively used in different…”
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17
IFT46 plays crucial roles in craniofacial and cilia development
Published in Biochemical and biophysical research communications (26-08-2016)“…The intraflagellar transport (IFT) system is essential for bidirectional movement of ciliary components from the basal body to the tip beneath the ciliary…”
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NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction
Published in Biochemical and biophysical research communications (14-10-2016)“…NSrp70 (nuclear speckle-related protein 70), a recently discovered protein and it belongs to the serine/arginine (SR) rich related protein family. NSrp70 is…”
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Lysine demethylase 3a in craniofacial and neural development during Xenopus embryogenesis
Published in International journal of molecular medicine (01-02-2019)“…Epigenetic modifier lysine demethylase 3a (Kdm3a) specifically demethylates mono‑ and di‑methylated ninth lysine of histone 3 and belongs to the Jumonji…”
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New acylated flavonoid glycosides from flowers of Aerva javanica
Published in Journal of asian natural products research (01-07-2013)“…Chromatographic purification of ethyl acetate soluble fraction of the methanolic extract of the flowers of Aerva javanica yielded three new acylated flavone…”
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