Search Results - "Ismail, Rania S. M."

Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents by Ismail, Rania S. M., El Kerdawy, Ahmed M., Soliman, Dalia H., Georgey, Hanan H., Abdel Gawad, Nagwa M., Angeli, Andrea, Supuran, Claudiu T.

“…An optimization strategy was adopted for designing and synthesizing new series of 2-oxindole conjugates. Selected compounds were evaluated for their…”
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Novel series of 6-(2-substitutedacetamido)-4-anilinoquinazolines as EGFR-ERK signal transduction inhibitors in MCF-7 breast cancer cells by Ismail, Rania S.M., Abou-Seri, Sahar M., Eldehna, Wagdy M., Ismail, Nasser S.M., Elgazwi, Sara M., Ghabbour, Hazem A., Ahmed, Mahmoud Salama, Halaweish, Fathi T., Abou El Ella, Dalal A.

“…Epidermal growth factor receptor (EGFR) signaling pathway has been previously investigated for its significant role in the progression of different types of…”
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Recent advances in 4-aminoquinazoline based scaffold derivatives targeting EGFR kinases as anticancer agents by Rania S.M. Ismail, Nasser S.M. Ismail, Sahar Abuserii, Dalal A. Abou El Ella

“…Quinazoline derivatives are fused heterocyclic ring systems which have been explored for their inhibitory activity towards various protein kinase enzymes and…”
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