Search Results - "Ismail, Noor Zafirah"
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Dichloromethane fraction of Moringa oleifera leaf methanolic extract selectively inhibits breast cancer cells (MCF7) by induction of apoptosis via upregulation of Bax, p53 and caspase 8 expressions
Published in Molecular biology reports (01-05-2021)“…Moringa oleifera is a well-known medicinal plant which has anti-cancer and other biological activities. This research aims to determine the cytotoxic and…”
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Christia vespertilionis extract induced antiproliferation and apoptosis in breast cancer (MCF7) cells
Published in Molecular biology reports (01-11-2021)“…Background C. vespertiliomis extracts were evaluated for antiproliferative and apoptosis effect on breast cancer (MCF7) cells. Methods and results The leaves…”
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Antioxidant Effects, Antiproliferative Effects, and Molecular Docking of Clinacanthus nutans Leaf Extracts
Published in Molecules (Basel, Switzerland) (29-04-2020)“…is a well-known herb that has been used as an alternative and therapeutic medicine, however more selective extracts are needed. In this study, leaves were…”
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Investigating the potential of mono-chalcone compounds in targeting breast cancer receptors through network pharmacology, molecular docking, molecular dynamics simulation, antiproliferative effects, and gene expressions
Published in 3 Biotech (01-06-2024)“…The study aims to investigate various aspects of synthesized mono-chalcone compounds 5 and 8 concerning breast cancer, including network pharmacology,…”
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Boswellia dalzielii-Mediated Silver Nanoparticles Inhibited Acute Myeloid Leukemia (AML) Kasumi-1 Cells by Inducing Cell Cycle Arrest
Published in Bioinorganic chemistry and applications (2020)“…Background. Acute myeloid leukemia (AML) persists to be a major health problem especially among children as effective chemotherapy to combat the disease is yet…”
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Synthesis and computational insights of hybrid heterocyclic bis-chalcone compounds and their cytotoxic effects against breast cancer cells
Published in Results in Chemistry (01-01-2024)“…[Display omitted] Breast cancer is a common disease that employs chemotherapeutic drugs as a treatment approach. However, these drugs have several adverse…”
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Tri-chalcone suppressed breast cancer cell proliferation and induced apoptosis through intrinsic and extrinsic pathways
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2024)“…Breast cancer development depends critically on antiproliferative and apoptotic mechanisms. However, the mechanisms underlying the antiproliferative and…”
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Network pharmacology, molecular docking and molecular dynamics simulation of chalcone scaffold-based compounds targeting breast cancer receptors
Published in Journal of biomolecular structure & dynamics (27-12-2023)“…Compounds with a chalcone scaffold-based structure have demonstrated promising anticancer biological activity. However, the molecular interactions between…”
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Synthesis, characterization and in silico studies of coumarin-chalcone derivatives and their cytotoxicity activity against breast cancer cells
Published in Journal of molecular structure (15-02-2025)“…•Eighteen new coumarin-chalcone compounds were designed, synthesized and characterized.•In vitro cytotoxicity activities were carried out on MCF-7 breast…”
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Molecular docking of compounds from Clinacanthus nutans extract detected by GC-MS analysis with the SARS-CoV-2 main protease and ACE2 protein
Published in Natural product research (01-06-2022)“…has been reported to have many medicinal properties and it is traditionally used in treating viral lesions. This study aims to determine the molecular docking…”
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Inhibitory Effect of Eco-Friendly Naturally Synthesized Silver Nanoparticles from the Leaf Extract of Medicinal Detarium microcarpum Plant on Pancreatic and Cervical Cancer Cells
Published in Asian Pacific journal of cancer prevention : APJCP (01-05-2020)“…Recently, nanoparticle synthesis by eco-friendly methods has received tremendous attention due to the method advantages and also because of the application of…”
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Low cytotoxicity, and antiproliferative activity on cancer cells, of the plant Senna alata (Fabaceae)
Published in Revista de biología tropical (01-03-2021)“…Introduction: The leaves of Senna alata from the Fabaceae family have been used in folk medicine for the cure of skin disease. In this study, we tested the…”
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Molecular docking and molecular dynamic simulations of apoptosis proteins with potential anticancer compounds present in Clinacanthus nutans extract using gas chromatography-mass spectrometry
Published in Journal of biomolecular structure & dynamics (02-09-2023)“…Clinacanthus nutans is a medicinal plant recognised for its anticancer properties. We previously discovered that the C. nutans extract had the most potent…”
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The antiproliferative and apoptotic potential of Clinacanthus nutans against human breast cancer cells through targeted apoptosis pathway
Published in Environmental science and pollution research international (01-11-2022)“…Clinacanthus nutans dichloromethane fraction (CN-Dcm) extract has previously been proven to suppress breast cancer (MCF7) cell proliferation. Despite this, the…”
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GC-MS Evaluation, Antioxidant Content, and Cytotoxic Activity of Propolis Extract from Peninsular Malaysian Stingless Bees, Tetrigona Apicalis
Published in Evidence-based complementary and alternative medicine (2020)“…Introduction. Propolis has been used traditionally in several countries for treating various diseases as it possessed healing properties including antioxidant…”
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Q-TOF LC-MS compounds evaluation of propolis extract derived from Malaysian stingless bees, Tetrigona apicalis, and their bioactivities in breast cancer cell, MCF7
Published in Saudi journal of biological sciences (01-10-2022)“…Propolis is known to exhibit various phytochemical compounds that aid in several biological activities. The current study investigates the phytochemical…”
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Compounds Evaluation and Cytotoxic Properties of Tetrigona apicalis Propolis Extract
Published in European journal of integrative medicine (01-12-2021)Get full text
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Determination of Phenolic and Flavonoid Contents, Antioxidant Activities and GC-MS Analysis of Clinacanthus nutans (Acanthaceae) in Different Locations
Published in Agrivita (01-10-2017)“…Clinacanthus nutans is an essential medicinal plant that had been used in various local remedies to treat many illnesses. A study had been conducted to…”
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Baja citotoxicidad, y actividad antiproliferativa sobre las celulas cancerosas, de la planta Senna alata
Published in Revista de biología tropical (01-03-2021)“…Introducción: Las hojas de Senna alata de la familia Fabaceae se han utilizado en la medicina popular para la cura de enfermedades de la piel. En este estudio,…”
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Evaluation of genetic diversity of Clinacanthus nutans (Acanthaceaea) using RAPD, ISSR and RAMP markers
Published in Physiology and molecular biology of plants (01-10-2016)“…Three polymerase chain reaction (PCR) techniques were compared to analyse the genetic diversity of Clinacanthus nutans eight populations in the northern region…”
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