Search Results - "Ismail, Abdullah"

Insulin gene expression is regulated by DNA methylation by Kuroda, Akio, Rauch, Tibor A, Todorov, Ivan, Ku, Hsun Teresa, Al-Abdullah, Ismail H, Kandeel, Fouad, Mullen, Yoko, Pfeifer, Gerd P, Ferreri, Kevin

“…Insulin is a critical component of metabolic control, and as such, insulin gene expression has been the focus of extensive study. DNA sequences that regulate…”
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Intestinal AMPK modulation of gut microbiota mediates cross‐talk with brown fat to control metabolism by Huang, Wendong, Zhang, Eryun, Jin, Lihua, Wang, Yangmeng, Fang, Zhipeng, Al‐Abdullah, Ismail, Shuck, Sarah

“…The energy‐dissipating capacity of brown adipose tissue through thermogenesis can be targeted to improve energy balance. Mammalian 5′‐AMP‐activated protein…”
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Chronic marijuana usage by human pancreas donors is associated with impaired islet function by Qi, Meirigeng, Kaddis, John S, Chen, Kuan-Tsen, Rawson, Jeffrey, Omori, Keiko, Chen, Zhen Bouman, Dhawan, Sangeeta, Isenberg, Jeffrey S, Kandeel, Fouad, Roep, Bart O, Al-Abdullah, Ismail H

“…We investigated the effect of chronic marijuana use, defined as 4 times weekly for more than 3 years, on human pancreatic islets. Pancreata from deceased…”
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The role of microRNAs in islet β-cell development by Kaviani, Maryam, Azarpira, Negar, Karimi, Mohammad Hossein, Al-Abdullah, Ismail

“…Cell‐based therapies suggest novel treatments to overcome the complication of the current therapeutic approaches in diabetes mellitus type 1. Replacement of…”
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Addressing knowledge gaps in allergies among Syrian hospital patients: a cross-sectional study by Ataya, Jamal, Ismail, Abdullah, Soqia, Jameel, Kousa, Alyamama, Shahoud, Zein, Alhalabi, Rawan, Zaitouna, Mazen

“…Allergies have a significant impact on health and quality of life worldwide, yet there is limited research on the awareness and knowledge of allergies. This…”
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Significant reduction of apoptosis induced via hypoxia and oxidative stress in isolated human islet by resveratrol by Keshtkar, Somayeh, Kaviani, Maryam, Jabbarpour, Zahra, Al- Abdullah, Ismail H., Aghdaei, Mahdokht H., Nikeghbalian, Saman, Shamsaeefar, Alireza, Geramizadeh, Bita, Azarpira, Negar, Ghahremani, Mohammad H.

“…Successful islet transplantation as a promising treatment of diabetes type 1 is threatened with the loss of islets during the pre-transplant culture due to…”
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Protective effect of nobiletin on isolated human islets survival and function against hypoxia and oxidative stress-induced apoptosis by Keshtkar, Somayeh, Kaviani, Maryam, Jabbarpour, Zahra, Geramizadeh, Bita, Motevaseli, Elahe, Nikeghbalian, Saman, Shamsaeefar, Alireza, Motazedian, Nasrin, Al-Abdullah, Ismail H., Ghahremani, Mohammad Hossein, Azarpira, Negar

“…Islets transplantation, as a treatment of type 1 diabetes, faces challenges, including the loss of islets in the process of isolation and pre-transplantation…”
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Forecasting tunnel geology, construction time and costs using machine learning methods by Mahmoodzadeh, Arsalan, Mohammadi, Mokhtar, Daraei, Ako, Farid Hama Ali, Hunar, Ismail Abdullah, Abdulqadir, Kameran Al-Salihi, Nawzad

“…This research intends to use machine learning approaches to predict tunnel geology and its construction time and costs. For this purpose, the Gaussian Process…”
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The impact of feature extraction and selection for the classification of gait patterns between ACL deficient and intact knees based on different classification models by Zeng, Wei, Ismail, Shiek Abdullah, Pappas, Evangelos

“…The anterior cruciate ligament (ACL) plays an important role in stabilizing translation and rotation of the tibia relative to the femur. Individuals with ACL…”
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Nanomedicine-based cancer immunotherapy: recent trends and future perspectives by Lakshmanan, Vinoth-Kumar, Jindal, Shlok, Packirisamy, Gopinath, Ojha, Shreesh, Lian, Sen, Kaushik, Ajeet, Alzarooni, Abdulqadir Ismail M. Abdullah, Metwally, Yasser Abdelraouf Farahat, Thyagarajan, Sadras Panchatcharam, Do Jung, Young, Chouaib, Salem

“…The combination of cancer immunotherapy with efficient functionalized nanosystems has emerged as a beneficial treatment strategy and its use has increased…”
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microRNAs in liver and kidney ischemia reperfusion injury: insight to improve transplantation outcome by Sabet Sarvestani, Fatemeh, Azarpira, Negar, Al-Abdullah, Ismail H., Tamaddon, Ali-Mohammad

“…[Display omitted] •Ischemia reperfusion injury (IRI) is often associated with microvascular dysfunction.•Production and release of inflammatory mediators in…”
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Biological hypoxia in pre-transplant human pancreatic islets induces transplant failure in diabetic mice by Kato, Hiroyuki, Salgado, Mayra, Mendez, Daniel, Gonzalez, Nelson, Rawson, Jeffrey, Ligot, Doreen, Balandran, Bennie, Orr, Chris, Quijano, Janine C., Omori, Keiko, Qi, Meirigeng, Al-Abdullah, Ismail H., Mullen, Yoko, Ku, Hsun Teresa, Kandeel, Fouad, Komatsu, Hirotake

“…Evaluating the quality of isolated human islets before transplantation is crucial for predicting the success in treating Type 1 diabetes. The current gold…”
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A scalable human islet 3D-culture platform maintains cell mass and function long-term for transplantation by Omori, Keiko, Qi, Meirigeng, Salgado, Mayra, Gonzalez, Nelson, Hui, Lauren T., Chen, Kuan-Tsen, Rawson, Jeffrey, Miao, Lynn, Komatsu, Hirotake, Isenberg, Jeffrey S., Al-Abdullah, Ismail H., Mullen, Yoko, Kandeel, Fouad

“…Present-day islet culture methods provide short-term maintenance of cell viability and function, limiting access to islet transplantation. Attempts to lengthen…”
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Thrombospondin-1, CD47, and SIRPα display cell-specific molecular signatures in human islets and pancreata by Erdem, Neslihan, Chen, Kuan-Tsen, Qi, Meirigeng, Zhao, Yuqi, Wu, Xiwei, Garcia, Isaac, Ku, Hsun Teresa, Montero, Enrique, Al-Abdullah, Ismail H, Kandeel, Fouad, Roep, Bart O, Isenberg, Jeffrey S

“…Thrombospondin-1 (TSP1) is a secreted protein minimally expressed in health but increased in disease and age. TSP1 binds to the cell membrane receptor CD47,…”
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Gene expression signature predicts human islet integrity and transplant functionality in diabetic mice by Kurian, Sunil M, Ferreri, Kevin, Wang, Chia-Hao, Todorov, Ivan, Al-Abdullah, Ismail H, Rawson, Jeffrey, Mullen, Yoko, Salomon, Daniel R, Kandeel, Fouad

“…There is growing evidence that transplantation of cadaveric human islets is an effective therapy for type 1 diabetes. However, gauging the suitability of islet…”
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Fluorogenic Peptide Substrate for Quantification of Bacterial Enzyme Activities by Al-Abdullah, Ismail H., Bagramyan, Karine, Bilbao, Shiela, Qi, Meirigeng, Kalkum, Markus

“…A novel peptide substrate (A G G P L G P P G P G G) was developed for quantifying the activities of bacterial enzymes using a highly sensitive Fluorescence…”
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Amelioration of the apoptosis-mediated death in isolated human pancreatic islets by minocycline by Kaviani, Maryam, Keshtkar, Somayeh, Azarpira, Negar, Aghdaei, Mahdokht Hossein, Geramizadeh, Bita, Karimi, Mohammad Hossein, Shamsaeefar, Alireza, Motazedian, Nasrin, Nikeghbalian, Saman, Al-Abdullah, Ismail H.

“…Minocycline functions as a therapeutic drug in different diseases because of its cytoprotective properties. In the present study, we examined the potential of…”
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Pancreatic human islets and insulin-producing cells derived from embryonic stem cells are rapidly identified by a newly developed Dithizone by Khiatah, Bashar, Qi, Meirigeng, Wu, Youjun, Chen, Kuan-Tsen, Perez, Rachel, Valiente, Luis, Omori, Keiko, Isenberg, Jeffrey S., Kandeel, Fouad, Yee, Jiing-Kuan, Al-Abdullah, Ismail H.

“…We developed an optimized Dipheylthiocarbazone or Dithizone (DTZ) with improved physical and chemical properties to characterize human islets and…”
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A Multiparametric Assessment of Human Islets Predicts Transplant Outcomes in Diabetic Mice by Komatsu, Hirotake, Qi, Meirigeng, Gonzalez, Nelson, Salgado, Mayra, Medrano, Leonard, Rawson, Jeffrey, Orr, Chris, Omori, Keiko, Isenberg, Jeffrey S., Kandeel, Fouad, Mullen, Yoko, Al-Abdullah, Ismail H.

“…Prior to transplantation into individuals with type 1 diabetes, in vitro assays are used to evaluate the quality, function and survival of isolated human…”
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Mechanism of Fatigue Crack Growth in Biomedical Alloy Ti-27Nb by Amjad, Muhammad, Badshah, Saeed, Rafique, Amer Farhan, Adil Khattak, Muhammad, Khan, Rafi Ullah, Abdullah Harasani, Wail Ismail

“…Implants are widely used in the human body for the replacement of affected bones. Fatigue failure is one of the serious concerns for implants. Therefore,…”
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